Effects of catecholamines on volemic replacement with saline solution and the impact on heart rate variability in rabbits subjected to hemorrhage. A study by spectral analysis
Moraes, José Mariano Soares de; Vane, Matheus Fachini; Rodrigues, Denise de Fátima; Mostarda, Cristiano Teixeira; Moraes, Thiago Soares Mendes Moreira de; Vane, Lucas Fachini; Ganem, Eliana Marisa; Cavalcanti, Ismar Lima; Módolo, Norma Sueli Pinheiro; Vane, Luiz Antonio.
Acta cir. bras.;
29(11): 703-710, Nov. 2014. tab, graf
Artigo
em Inglês
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| ID: vti-17693
Resumo
Twenty four rabbits subjected to hemorrhage (with a 25% loss of blood volume) and were randomly divided into four experimental groups: 1) HEMO Group underwent replacement with their own blood in an equal volume; 2) SS Group underwent replacement with saline solution (SS) in a volume that corresponded to three times the removed blood volume; 3) ISP Group underwent replacement with SS and isoprenaline; 4) FNL Group underwent replacement with SS and phenylephrine. Spectral Analysis of the heart rate and heart rate variability were performed from the recorded data. Hematocrit was measured throughout the experiment.RESULTS:Replacement with SS and an α- or β-agonist did not produce differences in the intravascular retention compared to replacement with SS alone. An analysis of HRV showed that the FNL group maintained the LF/HF ratio better than ISP and SS.CONCLUSIONS:No difference in vascular retention when α- or β- agonists were added to SS during post-hemorrhagic recovery. The animals in the FNL group maintained the integrity of the autonomic response within normal physiological standards during hemorrhagic stress.(AU)
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BR68.1
Localização: BR68.1
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