Metastatic seminoma in a male Alpine goat: clinical and histopathological approach
Cosentino, Isabel Oliveira; Balaro, Mario Felipe Alvarez; Carvalho, Ana Beatriz da Silva; Trevizan, Juliane Teramachi; Brandão, Felipe Zandonadi; Del Fava, Claudia.
Acta sci. vet. (Online);
47(suppl.1): Pub. 405, July 24, 2019. ilus
Artigo
em Inglês
| VETINDEX
| ID: vti-21495
Resumo
Background: Seminomas are germ cell tumors mainly originating from spermatogonia in the seminiferous tubules andhas been described in several domestic animal species, even though has rarely been described in goats. Moreover, seminomas tumors are not usually metastatic and rarely trigger paraneoplastic syndrome. In this sense, this is a case report ofa 12-year-old male Alpine goat, suspected of testicular neoplasm based on clinical examination and ultrasound imaging,diagnosed as a seminoma with metastasis in liver by histopathology upon necropsy.Case: A 12-year-old male Alpine goat presented a 10 month history of progressive weight loss, prostration, and scrotalsac enlargement. The major clinical findings were pale conjunctival mucus, bilateral nasal catarrhal secretion, obstructivedyspnea, an increased abdominal component, crackling at trachea auscultation, silence upon lung auscultation of the ventralarea and wheezing upon auscultation of the dorsal area, and enlargement of the left testicle with contralateral atrophy. Atthe Ultrasonography scan, the enlarged left testicle presented architecture loss, as well as circumscribed masses differingin echogenicity and echotexture with scattered small hyperechoic nodules. The shrunken right testicle showed acousticshading across the surface suggestive of calcification. Due to the poor prognosis and regard for animal welfare, the goatwas euthanized. The main necropsy findings on testicles were: enlarged left testicle with white parenchyma on the dorsalside as well as diffuse yellow elliptical lesions of 0.5-2.5 cm on the surface in association with two circumscribed areasat the cranial and caudal poles, firm upon cutting. The right testicle was half the typical size, slightly pale, firm at cuttingof the tunica albuginea, and presented dark parenchyma with abundant calcification dots suggestive of microlithiasis.The histological findings included diffuse tumoral stroma of the left testicle...(AU)
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Localização: BR68.1
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