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Adenocarcinoma pulmonar sólido primário em cão / Primary solid pulmonary adenocarcinoma in a dog

Oliveira, Mariana Correia; Costa, Samay Zillmann Rocha; Pires, Ana Paula de Castro; Gonçalves, Taïna; Fernandes, Júlio Israel; Camargo, Rodolfo Bettio Pires de; Nogueira, Vivian de Assunção.
Acta Sci. vet.; 47(suppl.1): Pub. 440, 18 nov. 2019. ilus
Artigo em Português | VETINDEX | ID: vti-25889


Background: In veterinary medicine, although primary lung tumors are rare compared to metastatic malignant neoplasms,an increase in the number of primary lung tumors in dogs has been reported in the past decades. Consequently, identifyingepidemiological, clinical, and pathological features of these neoplasms is essential for early and precise diagnosis. Thispaper aimed to report a case of a non-metastatic primary solid pulmonary adenocarcinoma in a dog and review the clinical,pathological, and immunohistochemical aspects of this neoplasm.Case: An 8-year-old female Cocker Spaniel was admitted to the Small Animals Veterinary Hospital of the Rural FederalUniversity of Rio de Janeiro (Brazil) with a history of progressive weight loss and clinical dyspnea. Physical examinationrevealed the following: body temperature, 38.7ºC; capillary refill time, one second; heart rate, 104 beats/min; respiratoryrate, 40 breaths/min; pallor mucosa; blood glucose, 133 mg/dL; and body score, 2 (1-9). A thoracic radiograph revealeda diffuse radiopaque pattern of the pulmonary parenchyma, pleural effusion, and a large mass that extended through bothhemithoraces. An ultrasound-guided cytological examination was performed and displayed moderate cellularity in a bloodybackground. Cells presented distinct cell borders, large bluish cytoplasm, round hyperchromatic or vesicular nuclei, andevident nucleoli. Three months after the first clinical consultation, the dogs state kept deteriorating and the owner optedfor the euthanasia. Autopsy of the lungs showed multiple, poorly defined, coalescent nodules with an average size of20.0×15.0×10.0 cm. The nodules occupied roughly 70% of the pulmonary...(AU)
Biblioteca responsável: BR68.1
Localização: BR68.1