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Effect of dietary selenium and vitamin E supplementation on testicular morphology and serum testosterone concentration in goats following scrotal insulation

Xavier, Guadalupe Carvalho; Soares, Pierre Castro; Silva Junior, Valdemiro Amaro da; Torres, Sandra Maria de; Maymone, Ana Cristina Marinho; Morais, Rosana Nogueira de; Moura, Cristiane Scavuzzi; Guerra, Maria Madalena Pessoa.
Acta sci. vet. (Online); 44: 01-08, 2016. ilus, tab
Artigo em Inglês | VETINDEX | ID: vti-722734

Resumo

Background: Heat directly applied to the testis has been providing information regarding the damage triggering mechanisms on spermatogenesis and possible treatments to prevent testicular changes. Testis submitted to heat-shock have inhibition of the local antioxidant defense mechanisms against lipid peroxidation and free radicals. Vitamin E and Selenium protect biological membranes against free radicals to prevent membrane lipid peroxidation. The current assay evaluated the effect of dietary supplementation with Selenium and Vitamin E on testicular parenchyma and testosterone levels of goats submitted to heat shock by scrotal insulation.Materials, Methods & Results: The effect of dietary selenium and vitamin E supplementation on testicular parameters and serum testosterone concentration was evaluated in goats subjected to scrotal insulation. The animals were randomly allocated into two groups (n = 6) to receive either a control diet (CO) or a diet supplemented with selenium and vitamin E (SE). The animals received supplementation for 120 days: 60 days prior to scrotal insulation, 18 days during scrotal insulation and 42 days after scrotal insulation. Orchiectomy was performed on three animals from each group, immediately after the end of scrotal insulation. The remaining animals were neutered at the end of the experimental period (120 days). Testicles were routinely process [...](AU)
Biblioteca responsável: BR68.1
Localização: BR68.1