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Acute myeloid leukemia in a dog chronically infected with leishmania spp. and other infectious agents / Leucemia mieloide aguda em cão infectado cronicamente por Leishmania spp. e outros agentes infecciosos
Bezerra, José Artur Brilhante; Rodrigues, Ramon Tadeu Galvão Alves; Lima, Isabelle de Oliveira; Vale, André Menezes do; Filgueira, Kilder Dantas.
Afiliação
  • Bezerra, José Artur Brilhante; Universidade Federal Rural do Semi-Árido. Hospital Veterinário. Mossoró. BR
  • Rodrigues, Ramon Tadeu Galvão Alves; Universidade Federal de Campina Grande. Patos. BR
  • Lima, Isabelle de Oliveira; Universidade Federal Rural do Semi-Árido. Hospital Veterinário. Mossoró. BR
  • Vale, André Menezes do; Universidade Federal Rural do Semi-Árido. Hospital Veterinário. Mossoró. BR
  • Filgueira, Kilder Dantas; Universidade Federal Rural do Semi-Árido. Hospital Veterinário. Mossoró. BR
Acta sci. vet. (Impr.) ; 46(supl): 1-4, 2018. ilus
Article em En | VETINDEX | ID: biblio-1457913
Biblioteca responsável: BR68.1
Localização: BR68.1
ABSTRACT

Background:

Rare studies have described the association of hematopoietic tumors and canine visceral leishmaniosis, however the association between the parasitary disease and neoplasia is still not well established in dogs. Thus, the aim of the present study was to report a case of acute myeloid leukemia (AML) in a dog infected by Leishmania spp. and other infectious agents.Case A 8-year-old, male Poodle, was brought to the Veterinary Hospital from Universidade Federal Rural do Semi-Árido. The dog had a history of recurrent tick-borne diseases, such as anaplasmosis, over the previous ten months. On physical examination, pale mucosa, enlargement of popliteal lymph nodes, onychogryphosis, purulent nasal discharge, and bilateral blepharitis with purulent discharge were observed. The dog was skinny and infested with ticks. The blood cell count revealed normocytic, normochromic anemia and leukocytosis (38.000/mm3 ) with neutrophilia (30.020/mm3 ). Serum biochemical tests demonstrated hyperproteinemia due to hyperglobulinemia, hypoalbuminemia, and an albuminglobulin ratio of 0.30. The immunochromathographic test for leishmaniasis was negative. The alterations observed in the bone marrow cytological analysis were suggestive of AML, and Anaplasma spp., Hepatozoon spp., and amastigote forms of Leishmania spp. were observed inside bone marrow cells. After diagnosis, a decision to euthanize the animal was made.

Discussion:

Few studies have demonstrated the presence of hematopoietic neoplasia in dogs chronically and simultaneously infected with multiple pathogens. A case of multiple myeloma in a dog associated with infection by Ehrlichia canis, A. phagocytophilum, L. infantum, and Dirofilaria immitis is described. Another study reported B-cell lymphoma in a dog with E. canis and Histoplasma capsulatum infection.[...]
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Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Acta sci. vet. (Impr.) / Acta sci. vet. (Online) Ano de publicação: 2018 Tipo de documento: Article
Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Acta sci. vet. (Impr.) / Acta sci. vet. (Online) Ano de publicação: 2018 Tipo de documento: Article