Peroneal nerve reconstruction by using glycerol-preserved veins: histological and functional assessment in rats
Cunha, Armando dos Santos; Costa, Marcio Paulino; Da Silva, Ciro Ferreira.
Acta cir. bras.;
28(2): 94-101, 2013. ilus, graf, tab
Artigo
em Inglês
| VETINDEX
| ID: vti-8957
Resumo
PURPOSE: To compare the degree of neural regeneration in rats upon interposition of autologous nerve graft, autogenous vein, glycerol-preserved autogenous vein, and glycerol-preserved allogeneic vein using qualitative and quantitative histological analyses as well as functional assessments. METHODS: Peroneal nerves were reconstructed differently in four groups of animals. Functional assessments were performed pre- and postoperatively for a period of six weeks. After six weeks, the animals were sacrificed and histological evaluations were performed. RESULTS: Histological patterns of autogenous veins without preservation showed pronounced neoangiogenesis and extensive axonal rarefaction, as confirmed by axonal counting and functional assessments. Glycerol-preserved veins had results similar to the control. CONCLUSIONS: Glycerol-preserved autogenous or allogeneic veins showed similar results to autograft results. The autogenous vein (without preservation in glycerol) presented histological and functional outcomes statistically lower than other groups.(AU)
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BR1.1
Localização: BR68.1
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