Detalhe da pesquisa
1.
Benzothiophenone Derivatives Targeting Mutant Forms of Estrogen Receptor-α in Hormone-Resistant Breast Cancers.
Int J Mol Sci
; 19(2)2018 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29462880
2.
Best Practices of Computer-Aided Drug Discovery: Lessons Learned from the Development of a Preclinical Candidate for Prostate Cancer with a New Mechanism of Action.
J Chem Inf Model
; 57(5): 1018-1028, 2017 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28441481
3.
Sequential Action of MalE and Maltose Allows Coupling ATP Hydrolysis to Translocation in the MalFGK2 Transporter.
J Biol Chem
; 290(42): 25452-60, 2015 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26338707
4.
Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.
J Biol Chem
; 289(38): 26417-26429, 2014 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25086042
5.
Two copies of the SecY channel and acidic lipids are necessary to activate the SecA translocation ATPase.
Proc Natl Acad Sci U S A
; 109(11): 4104-9, 2012 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22378651
6.
The maltose ABC transporter: action of membrane lipids on the transporter stability, coupling and ATPase activity.
Biochim Biophys Acta
; 1828(8): 1723-30, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23562402
7.
Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer.
Sci Rep
; 14(1): 7082, 2024 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38528115
8.
Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.
J Biol Chem
; 292(10): 4359, 2017 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28283588
9.
Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling.
J Biol Chem
; 287(21): 17530-17545, 2012 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22474287
10.
Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer.
Int J Mol Sci
; 14(6): 12496-519, 2013 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23771019
11.
Structure-Based Study to Overcome Cross-Reactivity of Novel Androgen Receptor Inhibitors.
Cells
; 11(18)2022 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36139361
12.
LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants.
Cell Rep
; 39(7): 110812, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35568025
13.
LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants.
bioRxiv
; 2022 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33972947
14.
Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.
J Biol Chem
; 290(43): 25850, 2015 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26500294
15.
The SecY complex forms a channel capable of ionic discrimination.
EMBO Rep
; 10(7): 762-8, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19483671
16.
Androgen receptor-binding sites are highly mutated in prostate cancer.
Nat Commun
; 11(1): 832, 2020 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32047165
17.
RPA nucleic acid-binding properties of IFI16-HIN200.
Biochim Biophys Acta
; 1784(7-8): 1087-97, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18472023
18.
Cheminformatics Driven Development of Novel Therapies for Drug Resistant Prostate Cancer.
Mol Inform
; 37(9-10): e1800043, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29733509
19.
Moving Towards Precision Urologic Oncology: Targeting Enzalutamide-resistant Prostate Cancer and Mutated Forms of the Androgen Receptor Using the Novel Inhibitor Darolutamide (ODM-201).
Eur Urol
; 73(1): 4-8, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28851578
20.
Small molecule-induced degradation of the full length and V7 truncated variant forms of human androgen receptor.
Eur J Med Chem
; 157: 1164-1173, 2018 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30193215