Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Bone resorption goes green.

Iqbal, Jameel; Zaidi, Mone.

Cell ; 184(5): 1137-1139, 2021 03 04.

Artigo em Inglês | MEDLINE | ID: mdl-33636131

2.

FSH blockade improves cognition in mice with Alzheimer's disease.

Xiong, Jing; Kang, Seong Su; Wang, Zhihao; Liu, Xia; Kuo, Tan-Chun; Korkmaz, Funda; Padilla, Ashley; Miyashita, Sari; Chan, Pokman; Zhang, Zhaohui; Katsel, Pavel; Burgess, Jocoll; Gumerova, Anisa; Ievleva, Kseniia; Sant, Damini; Yu, Shan-Ping; Muradova, Valeriia; Frolinger, Tal; Lizneva, Daria; Iqbal, Jameel; Goosens, Ki A; Gera, Sakshi; Rosen, Clifford J; Haroutunian, Vahram; Ryu, Vitaly; Yuen, Tony; Zaidi, Mone; Ye, Keqiang.

Nature ; 603(7901): 470-476, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-35236988

3.

Blocking FSH induces thermogenic adipose tissue and reduces body fat.

Liu, Peng; Ji, Yaoting; Yuen, Tony; Rendina-Ruedy, Elizabeth; DeMambro, Victoria E; Dhawan, Samarth; Abu-Amer, Wahid; Izadmehr, Sudeh; Zhou, Bin; Shin, Andrew C; Latif, Rauf; Thangeswaran, Priyanthan; Gupta, Animesh; Li, Jianhua; Shnayder, Valeria; Robinson, Samuel T; Yu, Yue Eric; Zhang, Xingjian; Yang, Feiran; Lu, Ping; Zhou, Yu; Zhu, Ling-Ling; Oberlin, Douglas J; Davies, Terry F; Reagan, Michaela R; Brown, Aaron; Kumar, T Rajendra; Epstein, Solomon; Iqbal, Jameel; Avadhani, Narayan G; New, Maria I; Molina, Henrik; van Klinken, Jan B; Guo, Edward X; Buettner, Christoph; Haider, Shozeb; Bian, Zhuan; Sun, Li; Rosen, Clifford J; Zaidi, Mone.

Nature ; 546(7656): 107-112, 2017 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-28538730

4.

Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass.

Kim, Se-Min; Taneja, Charit; Perez-Pena, Helena; Ryu, Vitaly; Gumerova, Anisa; Li, Wenliang; Ahmad, Naseer; Zhu, Ling-Ling; Liu, Peng; Mathew, Mehr; Korkmaz, Funda; Gera, Sakshi; Sant, Damini; Hadelia, Elina; Ievleva, Kseniia; Kuo, Tan-Chun; Miyashita, Hirotaka; Liu, Li; Tourkova, Irina; Stanley, Sarah; Lizneva, Daria; Iqbal, Jameel; Sun, Li; Tamler, Ronald; Blair, Harry C; New, Maria I; Haider, Shozeb; Yuen, Tony; Zaidi, Mone.

Proc Natl Acad Sci U S A ; 117(25): 14386-14394, 2020 06 23.

Artigo em Inglês | MEDLINE | ID: mdl-32513693

5.

First-in-class humanized FSH blocking antibody targets bone and fat.

Gera, Sakshi; Sant, Damini; Haider, Shozeb; Korkmaz, Funda; Kuo, Tan-Chun; Mathew, Mehr; Perez-Pena, Helena; Xie, Honglin; Chen, Hao; Batista, Rogerio; Ma, Kejun; Cheng, Zhen; Hadelia, Elina; Robinson, Cemre; Macdonald, Anne; Miyashita, Sari; Williams, Anthony; Jebian, Gregory; Miyashita, Hirotaka; Gumerova, Anisa; Ievleva, Kseniia; Smith, Pinar; He, Jiahuan; Ryu, Vitaly; DeMambro, Victoria; Quinn, Matthew A; Meseck, Marcia; Kim, Se-Min; Kumar, T Rajendra; Iqbal, Jameel; New, Maria I; Lizneva, Daria; Rosen, Clifford J; Hsueh, Aaron J; Yuen, Tony; Zaidi, Mone.

Proc Natl Acad Sci U S A ; 117(46): 28971-28979, 2020 11 17.

Artigo em Inglês | MEDLINE | ID: mdl-33127753

6.

Oxytocin regulates body composition.

Sun, Li; Lizneva, Daria; Ji, Yaoting; Colaianni, Graziana; Hadelia, Elina; Gumerova, Anisa; Ievleva, Kseniia; Kuo, Tan-Chun; Korkmaz, Funda; Ryu, Vitaly; Rahimova, Alina; Gera, Sakshi; Taneja, Charit; Khan, Ayesha; Ahmad, Naseer; Tamma, Roberto; Bian, Zhuan; Zallone, Alberta; Kim, Se-Min; New, Maria I; Iqbal, Jameel; Yuen, Tony; Zaidi, Mone.

Proc Natl Acad Sci U S A ; 116(52): 26808-26815, 2019 Dec 26.

Artigo em Inglês | MEDLINE | ID: mdl-31843930

7.

Epitope-specific monoclonal antibodies to FSHß increase bone mass.

Ji, Yaoting; Liu, Peng; Yuen, Tony; Haider, Shozeb; He, Jiahuan; Romero, Raquel; Chen, Hao; Bloch, Madison; Kim, Se-Min; Lizneva, Daria; Munshi, Lubna; Zhou, Chunxue; Lu, Ping; Iqbal, Jameel; Cheng, Zhen; New, Maria I; Hsueh, Aaron J; Bian, Zhuan; Rosen, Clifford J; Sun, Li; Zaidi, Mone.

Proc Natl Acad Sci U S A ; 115(9): 2192-2197, 2018 02 27.

Artigo em Inglês | MEDLINE | ID: mdl-29440419

8.

Cytochrome c oxidase dysfunction enhances phagocytic function and osteoclast formation in macrophages.

Angireddy, Rajesh; Kazmi, Hasan Raza; Srinivasan, Satish; Sun, Li; Iqbal, Jameel; Fuchs, Serge Y; Guha, Manti; Kijima, Takashi; Yuen, Tony; Zaidi, Mone; Avadhani, Narayan G.

FASEB J ; 33(8): 9167-9181, 2019 08.

Artigo em Inglês | MEDLINE | ID: mdl-31063702

9.

Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cancer.

Stachnik, Agnes; Yuen, Tony; Iqbal, Jameel; Sgobba, Miriam; Gupta, Yogesh; Lu, Ping; Colaianni, Graziana; Ji, Yaoting; Zhu, Ling-Ling; Kim, Se-Min; Li, Jianhua; Liu, Peng; Izadmehr, Sudeh; Sangodkar, Jaya; Scherer, Thomas; Mujtaba, Shiraz; Galsky, Matthew; Gomez, Jorge; Epstein, Solomon; Buettner, Christoph; Bian, Zhuan; Zallone, Alberta; Aggarwal, Aneel K; Haider, Shozeb; New, Maria I; Sun, Li; Narla, Goutham; Zaidi, Mone.

Proc Natl Acad Sci U S A ; 111(50): 17995-8000, 2014 Dec 16.

Artigo em Inglês | MEDLINE | ID: mdl-25453078

10.

Bisphosphonates inactivate human EGFRs to exert antitumor actions.

Yuen, Tony; Stachnik, Agnes; Iqbal, Jameel; Sgobba, Miriam; Gupta, Yogesh; Lu, Ping; Colaianni, Graziana; Ji, Yaoting; Zhu, Ling-Ling; Kim, Se-Min; Li, Jianhua; Liu, Peng; Izadmehr, Sudeh; Sangodkar, Jaya; Bailey, Jack; Latif, Yathin; Mujtaba, Shiraz; Epstein, Solomon; Davies, Terry F; Bian, Zhuan; Zallone, Alberta; Aggarwal, Aneel K; Haider, Shozeb; New, Maria I; Sun, Li; Narla, Goutham; Zaidi, Mone.

Proc Natl Acad Sci U S A ; 111(50): 17989-94, 2014 Dec 16.

Artigo em Inglês | MEDLINE | ID: mdl-25453081

11.

Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes.

Iqbal, Jameel; Sun, Li; Cao, Jay; Yuen, Tony; Lu, Ping; Bab, Itai; Leu, N Adrian; Srinivasan, Satish; Wagage, Sagie; Hunter, Christopher A; Nebert, Daniel W; Zaidi, Mone; Avadhani, Narayan G.

Proc Natl Acad Sci U S A ; 110(27): 11115-20, 2013 Jul 02.

Artigo em Inglês | MEDLINE | ID: mdl-23776235

12.

Gaucher disease gene GBA functions in immune regulation.

Liu, Jun; Halene, Stephanie; Yang, Mei; Iqbal, Jameel; Yang, Ruhua; Mehal, Wajahat Z; Chuang, Wei-Lien; Jain, Dhanpat; Yuen, Tony; Sun, Li; Zaidi, Mone; Mistry, Pramod K.

Proc Natl Acad Sci U S A ; 109(25): 10018-23, 2012 Jun 19.

Artigo em Inglês | MEDLINE | ID: mdl-22665763

13.

Bone marrow oxytocin mediates the anabolic action of estrogen on the skeleton.

Colaianni, Graziana; Sun, Li; Di Benedetto, Adriana; Tamma, Roberto; Zhu, Ling-Ling; Cao, Jay; Grano, Maria; Yuen, Tony; Colucci, Sylvia; Cuscito, Concetta; Mancini, Lucia; Li, Jianhua; Nishimori, Katsuhiko; Bab, Itai; Lee, Heon-Jin; Iqbal, Jameel; Young, W Scott; Rosen, Clifford; Zallone, Alberta; Zaidi, Mone.

J Biol Chem ; 287(34): 29159-67, 2012 Aug 17.

Artigo em Inglês | MEDLINE | ID: mdl-22761429

14.

Translational medicine: Double protection for weakened bones.

Zaidi, Mone; Iqbal, Jameel.

Nature ; 485(7396): 47-8, 2012 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-22552091

15.

ACTH protects against glucocorticoid-induced osteonecrosis of bone.

Zaidi, Mone; Sun, Li; Robinson, Lisa J; Tourkova, Irina L; Liu, Li; Wang, Yujuan; Zhu, Ling-Ling; Liu, Xuan; Li, Jianhua; Peng, Yuanzhen; Yang, Guozhe; Shi, Xingming; Levine, Alice; Iqbal, Jameel; Yaroslavskiy, Beatrice B; Isales, Carlos; Blair, Harry C.

Proc Natl Acad Sci U S A ; 107(19): 8782-7, 2010 May 11.

Artigo em Inglês | MEDLINE | ID: mdl-20421485

16.

Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage.

Mistry, Pramod K; Liu, Jun; Yang, Mei; Nottoli, Timothy; McGrath, James; Jain, Dhanpat; Zhang, Kate; Keutzer, Joan; Chuang, Wei-Lien; Chuang, Wei-Lein; Mehal, Wajahat Z; Zhao, Hongyu; Lin, Aiping; Mane, Shrikant; Liu, Xuan; Peng, Yuan Z; Li, Jian H; Agrawal, Manasi; Zhu, Ling-Ling; Blair, Harry C; Robinson, Lisa J; Iqbal, Jameel; Sun, Li; Zaidi, Mone.

Proc Natl Acad Sci U S A ; 107(45): 19473-8, 2010 Nov 09.

Artigo em Inglês | MEDLINE | ID: mdl-20962279

17.

Disease-drug pairs revealed by computational genomic connectivity mapping on GBA1 deficient, Gaucher disease mice.

Yuen, Tony; Iqbal, Jameel; Zhu, Ling-Ling; Sun, Li; Lin, Aiping; Zhao, Hongyu; Liu, Jun; Mistry, Pramod K; Zaidi, Mone.

Biochem Biophys Res Commun ; 422(4): 573-7, 2012 Jun 15.

Artigo em Inglês | MEDLINE | ID: mdl-22588172

18.

Physiological loading of joints prevents cartilage degradation through CITED2.

Leong, Daniel J; Li, Yong H; Gu, Xiang I; Sun, Li; Zhou, Zuping; Nasser, Philip; Laudier, Damien M; Iqbal, Jameel; Majeska, Robert J; Schaffler, Mitchell B; Goldring, Mary B; Cardoso, Luis; Zaidi, Mone; Sun, Hui B.

FASEB J ; 25(1): 182-91, 2011 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-20826544

19.

Oxytocin is an anabolic bone hormone.

Tamma, Roberto; Colaianni, Graziana; Zhu, Ling-ling; DiBenedetto, Adriana; Greco, Giovanni; Montemurro, Gabriella; Patano, Nicola; Strippoli, Maurizio; Vergari, Rosaria; Mancini, Lucia; Colucci, Silvia; Grano, Maria; Faccio, Roberta; Liu, Xuan; Li, Jianhua; Usmani, Sabah; Bachar, Marilyn; Bab, Itai; Nishimori, Katsuhiko; Young, Larry J; Buettner, Christoph; Iqbal, Jameel; Sun, Li; Zaidi, Mone; Zallone, Alberta.

Proc Natl Acad Sci U S A ; 106(17): 7149-54, 2009 Apr 28.

Artigo em Inglês | MEDLINE | ID: mdl-19369205

20.

Reverse cholesterol transport and hepatic osteodystrophy.

Zaidi, Mone; Yuen, Tony; Iqbal, Jameel.

Cell Metab ; 34(3): 347-349, 2022 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-35235770

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