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1.
Clin Oral Implants Res ; 34(2): 116-126, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36458928

RESUMO

BACKGROUND: The fixture thread depth reportedly influences the primary stability of dental implant, but its effect on the positional accuracy in immediate implant placement has not been reported previously. MATERIALS AND METHODS: Fifty-six single-rooted, anterior and premolar teeth were extracted from six human cadavers, followed by installing either regular-threaded implants (RT group, N = 30) or deep-threaded implants (DT group, N = 26) completely relying on the surgical guide. Optical impressions taken after osteotomy and fixture installation were superimposed with the preoperative virtual planning data to measure the vertical, angular, platform and apex deviations that occurred during osteotomy and installation. RESULTS: While the osteotomy deviations were similar between the two groups, the angular and apex deviation of the DT group (2.67 ± 2.56°; 1.04 ± 0.49 mm, respectively) were significantly larger than those of the RT group (1.61 ± 1.04°; 0.67 ± 0.41 mm, respectively) during installation (p < .05). When the installation deviations were analysed in the anterior and premolar areas separately, the angular, platform and apex deviations of the DT group (3.05 ± 3.26°; 0.75 ± 0.32 mm; 1.08 ± 0.56 mm, respectively) were significantly larger than those of the RT group (1.56 ± 0.73°, 0.59 ± 0.28 mm; 0.62 ± 0.38 mm, respectively) in the anterior site (p < .05), whereas there was no significant intergroup difference in the premolar site. CONCLUSION: In immediate-implant surgery, using an implant with a deeper thread might increase the deviations during installation, especially in the anterior area.


Assuntos
Implantes Dentários , Cirurgia Assistida por Computador , Humanos , Implantação Dentária Endóssea , Tomografia Computadorizada de Feixe Cônico , Cadáver , Desenho Assistido por Computador , Imageamento Tridimensional
2.
BMC Musculoskelet Disord ; 22(1): 892, 2021 Oct 20.
Artigo em Inglês | MEDLINE | ID: mdl-34670523

RESUMO

BACKGROUND: Acetabular prosthesis positioning in total hip arthroplasty (THA) is crucial in reducing the risk of dislocation. There has been minimal research on the proper way to put the acetabular components into the safe zone intraoperatively. Assessment of version by intraoperative imaging intensifier is very valuable. The value of Widmer's method, using the intraoperative C-arm available to determine cup anteversion was assessed. METHODS: One hundred one hips in 91 patients who underwent primary THA were eligible for inclusion. Utilizing intraoperative C-arm images, measurement was performed using the technique described by Widmer. The values obtained using 3D computed tomography postoperatively, which determined the anteversion of the acetabular component, were regarded as the reference standard. RESULTS: The method of Widmer obtained values similar to those obtained using 3D computed tomography and was considered accurate (n.s.). All 101 hips were positioned in the set target zone. Among the 101 hips, the cup position in nine hips (8.9%) was changed. The dislocation rate in our study was 1.0% with all dislocations occurring in hips placed in the target zone. The mean Harris hip score after THA in 1 year was 94.2 (82-98). CONCLUSIONS: The method of Widmer was accurate using intraoperative imaging intensifier for the measurement of the anteversion of the acetabular component during THA, with reference to the anteversion obtained from the 3D computed tomography. Also, utilizing intraoperative C-arm imaging was very useful because it allowed for correction of the position of the acetabular cup.


Assuntos
Artroplastia de Quadril , Prótese de Quadril , Luxações Articulares , Acetábulo/diagnóstico por imagem , Acetábulo/cirurgia , Artroplastia de Quadril/efeitos adversos , Humanos , Intensificação de Imagem Radiográfica
3.
Sensors (Basel) ; 21(24)2021 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-34960470

RESUMO

Urban scene modeling is a challenging but essential task for various applications, such as 3D map generation, city digitization, and AR/VR/metaverse applications. To model man-made structures, such as roads and buildings, which are the major components in general urban scenes, we present a clustering-based plane segmentation neural network using 3D point clouds, called hybrid K-means plane segmentation (HKPS). The proposed method segments unorganized 3D point clouds into planes by training the neural network to estimate the appropriate number of planes in the point cloud based on hybrid K-means clustering. We consider both the Euclidean distance and cosine distance to cluster nearby points in the same direction for better plane segmentation results. Our network does not require any labeled information for training. We evaluated the proposed method using the Virtual KITTI dataset and showed that our method outperforms conventional methods in plane segmentation. Our code is publicly available.


Assuntos
Redes Neurais de Computação , Análise por Conglomerados , Humanos
4.
Soft Matter ; 16(25): 5840-5847, 2020 Jul 07.
Artigo em Inglês | MEDLINE | ID: mdl-32463053

RESUMO

For the facile use of liquid metal composites (LMCs) for soft, stretchable and thermal systems, it is crucial to understand and predict the thermal conductivity of the composites as a function of liquid metal (LM) volume fraction and applied strain. In this study, we investigated the effective thermal conductivity of LMCs based on various mean-field homogenization frameworks including Eshelby, Mori-Tanaka, differential and double inclusion methods. The double inclusion model turned out to make the prediction closest to the experimental results in a wide range of LM volume fractions. Interestingly, we found that the theoretical models based on the assumption of ideal LM dispersion and zero interfacial resistance underestimated the thermal conductivity compared to the experimental results in a low volume fraction regime. By considering the accompanied variations in the LM inclusion's aspect ratios under a typical size distribution of inclusions (∼µm), the change of effective thermal conductivity was predicted under a uniaxial 300% tensile strain. Our study will deepen the understanding of the thermal properties of LMCs and support the designs of stretchable thermal interfaces and packaging with LMCs in the future.

5.
J Org Chem ; 84(10): 6258-6269, 2019 05 17.
Artigo em Inglês | MEDLINE | ID: mdl-30994355

RESUMO

We report redox-driven folding, unfolding, and refolding motions of a synthetic molecular system, in which two tetrathiafulvalene (TTF) units are tethered onto a conformationally rigid yet torsionally flexible π-conjugated backbone. Upon one-electron oxidation, this molecular switch undergoes swiveling motions from a fully relaxed and freely rotating Z-shaped conformation to a compact folded conformation stabilizing π-stacked radical species. Subsequent one-electron oxidation produces dicationic intermediates, which either engage in intimate π-π interactions or transition to an open structure. Further oxidation, however, brings the molecule back to the initial conformation to minimize the repulsion between doubly-charged TTF units. Intriguingly, the reaction coordinates of this redox-driven structural change have strong dependence on the environment, such as the solvent (THF vs CH2Cl2) and supporting electrolyte (PF6- vs B(C6F5)4-). With a proper design, factors that are typically considered as "secondary effects" could dictate the solution dynamics and reaction pathways of structural folding and unfolding, all driven by controlled delivery of electrons.

6.
Sensors (Basel) ; 18(1)2018 Jan 04.
Artigo em Inglês | MEDLINE | ID: mdl-29300338

RESUMO

A wireless sensor network (WSN) is emerging as an innovative method for gathering information that will significantly improve the reliability and efficiency of infrastructure systems. Broadcast is a common method to disseminate information in WSNs. A variety of counter-based broadcast schemes have been proposed to mitigate the broadcast-storm problems, using the count threshold value and a random access delay. However, because of the limited propagation of the broadcast-message, there exists a trade-off in a sense that redundant retransmissions of the broadcast-message become low and energy efficiency of a node is enhanced, but reachability become low. Therefore, it is necessary to study an efficient counter-based broadcast scheme that can dynamically adjust the random access delay and count threshold value to ensure high reachability, low redundant of broadcast-messages, and low energy consumption of nodes. Thus, in this paper, we first measure the additional coverage provided by a node that receives the same broadcast-message from two neighbor nodes, in order to achieve high reachability with low redundant retransmissions of broadcast-messages. Second, we propose a new counter-based broadcast scheme considering the size of the additional coverage area, distance between the node and the broadcasting node, remaining battery of the node, and variations of the node density. Finally, we evaluate performance of the proposed scheme compared with the existing counter-based broadcast schemes. Simulation results show that the proposed scheme outperforms the existing schemes in terms of saved rebroadcasts, reachability, and total energy consumption.

7.
Sensors (Basel) ; 17(10)2017 Oct 14.
Artigo em Inglês | MEDLINE | ID: mdl-29036924

RESUMO

Recently, the development of wireless body area sensor network (WBASN) has accelerated due to the rapid development of wireless technology. In the WBASN environment, many WBASNs coexist where communication ranges overlap with each other, resulting in the possibility of interference. Although nodes in a WBASN typically operate at a low power level, to avoid adversely affecting the human body, high transmission rates may be required to support some applications. In addition to this, since many varieties of applications exist in the WBASN environment, each prospective user may have different quality of service (QoS) requirements. Hence, the following issues should be considered in the WBASN environment: (1) interference between adjacent WBASNs, which influences the performance of a specific system, and (2) the degree of satisfaction on the QoS of each user, i.e., the required QoS such as user throughput should be considered to ensure that all users in the network are provided with a fair QoS satisfaction. Thus, in this paper, we propose a transmission power adjustment algorithm that addresses interference problems and guarantees QoS fairness between users. First, we use a new utility function to measure the degree of the satisfaction on the QoS for each user. Then, the transmission power of each sensor node is calculated using the Cucker-Smale model, and the QoS satisfaction of each user is synchronized dispersively. The results of simulations show that the proposed algorithm performs better than existing algorithms, with respect to QoS fairness and energy efficiency.

8.
J Food Sci Technol ; 54(7): 1837-1849, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28720939

RESUMO

Information on cholesterol intake through restaurant meal is of high concern because of increasing eat-out population. Since nutrient labeling is not mandatory for restaurant food in Korea, cholesterol database on restaurant menu is unavailable. This study was performed to construct regional and national cholesterol database on primary Korean restaurant foods including 30 soup/stew, 24 rice dishes, and 27 noodles. From 2009 to 2012, Korea Ministry of Food and Drug Safety collected total 5832 foods (81 food types ×6 regions ×12 restaurants) nationwide and then 486 composites representing food types and regions were prepared for cholesterol analysis. Cholesterol contents of 486 composite samples were highly affected by recipe, food type, seasonality of ingredients, and geographical location, showing the range of 1.1-143.0, 1.5-85.1, and 0.4-62.2 mg/100 g for soup/stew, rice dishes, and noodles, respectively. The highest cholesterol value was observed in Al-tang (spicy fish roe soup) while Maemil-guksu (buckwheat noodle in beef stock) showed the lowest among all samples. Most foods contain relatively low cholesterol content, but the serving size and consumption frequency of dishes should be considered in order not to exceed the recommended daily intake limit (300 mg cholesterol). Saponification coupled with gas chromatography applied for cholesterol analysis was reliable based on accuracy (95% > recovery) and precision (repeatability <4% and reproducibility <8%). Quality control chart monitored for 4 years showed that all analyses were under the control. This study provides reliable and representative cholesterol contents of Korean restaurant key foods, which can be utilized for assessments of cholesterol intake in the current Korean diet.

9.
Bioprocess Biosyst Eng ; 39(1): 159-67, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26566954

RESUMO

In this study, the environmental adaptive metabolic processes were investigated using a psychrotrophic polar bacterium Bacillus pumilus PAMC 23174 in response to various temperatures and nutrients, especially in regard to the synthesis of fatty acids. Fatty acid methyl ester analysis was performed using gas chromatography-mass spectrometry and we found that a sensitive changes in iso-branched fatty acid (iso-15:0) synthesis occurred when adjusting the nutritional ratio of branched chain fatty acids (anteiso/iso) with different temperatures, resulting in a change in the balance of anteiso- and iso-form fatty acids. We also observed that this Arctic bacterium preferred amino acid leucine for the synthesis of fatty acids. The increased and decreased synthesis of iso-form fatty acids in response to different temperatures and leucine preference, changes the fatty acid ratio in bacteria, which further affects the membrane fluidity and it is also directly correlated with survival of bacteria in an extreme environment. Hence, this study suggests that B. pumilus PAMC 23174 is a potential model organism for the analysis of the unique ecological adaptations of polar bacteria in changing and the extreme environments.


Assuntos
Aclimatação , Bacillus/crescimento & desenvolvimento , Ácidos Graxos/biossíntese , Modelos Biológicos
10.
Sensors (Basel) ; 16(10)2016 Oct 12.
Artigo em Inglês | MEDLINE | ID: mdl-27754315

RESUMO

With the arrival of the era of Internet of Things (IoT), Wi-Fi Direct is becoming an emerging wireless technology that allows one to communicate through a direct connection between the mobile devices anytime, anywhere. In Wi-Fi Direct-based IoT networks, all devices are categorized by group of owner (GO) and client. Since portability is emphasized in Wi-Fi Direct devices, it is essential to control the energy consumption of a device very efficiently. In order to avoid unnecessary power consumed by GO, Wi-Fi Direct standard defines two power-saving methods: Opportunistic and Notice of Absence (NoA) power-saving methods. In this paper, we suggest an algorithm to enhance the energy efficiency of Wi-Fi Direct power-saving, considering the characteristics of multimedia video traffic. Proposed algorithm utilizes the statistical distribution for the size of video frames and adjusts the lengths of awake intervals in a beacon interval dynamically. In addition, considering the inter-dependency among video frames, the proposed algorithm ensures that a video frame having high priority is transmitted with higher probability than other frames having low priority. Simulation results show that the proposed method outperforms the traditional NoA method in terms of average delay and energy efficiency.

11.
J Proteome Res ; 13(9): 4047-61, 2014 Sep 05.
Artigo em Inglês | MEDLINE | ID: mdl-25087458

RESUMO

Sleep deprivation (SD) can influence cognition, memory, and sleep/wake homeostasis and can cause impairments in many physiological processes. Because the homeostatic control of the sleep/wake cycle is closely associated with the hypothalamus, the current study was undertaken to examine proteomic changes occurring in hypothalamic astrocytes following chronic partial SD. After chronic partial SD for 7 days, astrocytes were prepared from rat hypothalamus using a Percoll gradient method, and their proteome profiles were determined by LC-MS/MS. Comparisons of the proteome profiles of hypothalamic astrocytes revealed that chronic partial SD increased (≥1.5-fold) 89 proteins and decreased (≤0.7-fold) 50 proteins; these changes in protein expression were validated by western blot or immunohistochemistry. DAVID and IPA analyses of these proteins suggested that SD may influence gliotransmission and astrocyte activation. PPP2R1A, RTN4, VAMP-2, LGI-1, and SLC17A7 were identified and validated as the main targets of SD in astrocytes. Our results suggest that SD may modulate gliotransmission in the hypothalamus, thereby disturbing sleep/wake homeostasis and increasing susceptibility to neurological disease; however, further studies are required to confirm whether the proteome changes are specific to SD.


Assuntos
Astrócitos/metabolismo , Hipotálamo/citologia , Proteoma/análise , Proteômica/métodos , Privação do Sono/metabolismo , Animais , Astrócitos/química , Hipotálamo/metabolismo , Masculino , Proteoma/química , Proteoma/metabolismo , Ratos , Ratos Sprague-Dawley , Espectrometria de Massas em Tandem
12.
Plant Physiol ; 163(3): 1203-17, 2013 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24092888

RESUMO

The function of a putative galacturonosyltransferase from Arabidopsis (Arabidopsis thaliana; At1g02720; GALACTURONOSYLTRANSFERASE-LIKE5 [AtGATL5]) was studied using a combination of molecular genetic, chemical, and immunological approaches. AtGATL5 is expressed in all plant tissues, with highest expression levels in siliques 7 DPA. Furthermore, its expression is positively regulated by several transcription factors that are known to regulate seed coat mucilage production. AtGATL5 is localized in both endoplasmic reticulum and Golgi, in comparison with marker proteins resident to these subcellular compartments. A transfer DNA insertion in the AtGATL5 gene generates seed coat epidermal cell defects both in mucilage synthesis and cell adhesion. Transformation of atgatl5-1 mutants with the wild-type AtGATL5 gene results in the complementation of all morphological phenotypes. Compositional analyses of the mucilage isolated from the atgatl5-1 mutant demonstrated that galacturonic acid and rhamnose contents are decreased significantly in atgatl5-1 compared with wild-type mucilage. No changes in structure were observed between soluble mucilage isolated from wild-type and mutant seeds, except that the molecular weight of the mutant mucilage increased 63% compared with that of the wild type. These data provide evidence that AtGATL5 might function in the regulation of the final size of the mucilage rhamnogalacturonan I.


Assuntos
Proteínas de Arabidopsis/metabolismo , Arabidopsis/metabolismo , Mucilagem Vegetal/metabolismo , Sementes/metabolismo , Arabidopsis/genética , Proteínas de Arabidopsis/genética , Retículo Endoplasmático/metabolismo , Regulação da Expressão Gênica de Plantas , Teste de Complementação Genética , Complexo de Golgi/metabolismo , Proteínas de Fluorescência Verde/genética , Proteínas de Fluorescência Verde/metabolismo , Ácidos Hexurônicos/metabolismo , Hibridização In Situ , Microscopia Confocal , Microscopia Eletrônica de Varredura , Mutação , Análise de Sequência com Séries de Oligonucleotídeos , Pectinas/metabolismo , Mucilagem Vegetal/análise , Plantas Geneticamente Modificadas , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Ramnose/metabolismo , Sementes/genética , Sementes/ultraestrutura , Transcriptoma
13.
BMC Sports Sci Med Rehabil ; 16(1): 51, 2024 Feb 21.
Artigo em Inglês | MEDLINE | ID: mdl-38378630

RESUMO

BACKGROUND: Cardiac rehabilitation (CR) is recommended for patients with cardiovascular disease. However, the participation and completion rates for hospital-based CR are low, and home-based CR has been suggested as an alternative. This study aimed to develop a home-based CR program and assess the feasibility of the program over a 6-week period in patients with left ventricular dysfunction or a history of myocardial infarction. METHODS: This feasibility study consisted of two phases. The initial phase (Study 1) focused on developing the home-based exercise protocol. Systematic approaches to developing evidence-based home-based exercise intervention were implemented including systematic review, patient surveys, and expert consensus. Study 2 aimed to evaluate the feasibility of a 6-week home-based CR program that was based on the results of Study 1. Study 2 included two exercise education sessions and four telephone counseling sessions. During this stage of the exercise program, the participants exercised on two separate days and their experiences while performing the aerobic and resistance exercises were surveyed. Eight participants participated in Study 1 and 16 participated in Study 2. RESULTS: Participants expressed overall satisfaction with the exercise program in Study 1. Heart rate increased in response to exercise, but this did not correspond with perceived exertion. The aim of the home-based CR exercise program was for participants to achieve exercise goals (≥150 min/week of aerobic type exercises as well as at least twice weekly resistance exercise using own body weights). We aimed to increase compliance and adherence to the home-based CR program. In Study 2, 13 out of 16 participants (81.3%) completed the 6-week home-based CR program, with a participation rate of 100% in both exercise education and phone counseling sessions. Adherence to the home-based exercise protocol was 83.1% and no serious adverse events were observed. At the beginning of the study, only three out of 13 participants (23.1%) met the requirements for both aerobic and resistance exercises, but at the end of the 6-week program, 10 out of 13 participants (76.9%) fulfilled the requirements. CONCLUSION: The exercise program developed in this study was safe and feasible, and the 6-week home-based CR program was feasible for patients with cardiovascular disease without any reported adverse effects.

14.
Chemistry ; 19(16): 5156-68, 2013 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-23447364

RESUMO

A series of C2-symmetric chiral tetra-dentate ligands were prepared by using [4,5]- or [5,6]-pinene-fused 2,2'-bipyridyl units that are supported across a rigid arylene-ethynylene backbone. These conformationally pre-organised chelates support stable 1:1 metal complexes, which were fully characterised by UV/Vis, fluorescence, circular dichroism (CD), and (1)H NMR spectroscopy. A careful inspection of the exciton-coupled circular dichroism (ECCD) and (1)H NMR spectra of the reaction mixture in solution, however, revealed the evolution and decay of intermediate species en route to the final 1:1 metal-ligand adduct. Consistent with this model, mass spectrometric analysis revealed the presence of multiple metal complexes in solution at high ligand-to-metal ratios, which were essentially unobservable by UV/Vis or fluorescence spectroscopic techniques. Comparative studies with a bi-dentate model system have fully established the functional role of the π-conjugated ligand skeleton that dramatically enhances the thermodynamic stability of the 1:1 complex. In addition to serving as a useful spectroscopic handle to understand the otherwise "invisible" solution dynamics of this metal-ligand assembly process, temperature-dependent changes in the proton resonances associated with the chiral ligands allowed us to determine the activation barrier (ΔG(≠)) for the chirality switching between the thermodynamically stable but kinetically labile (P)- and (M)-stereoisomers.


Assuntos
Complexos de Coordenação/química , Espectroscopia de Ressonância Magnética/métodos , Naftalenos/química , Naftóis/química , Zinco/química , Dicroísmo Circular , Ligantes , Conformação Molecular , Soluções , Estereoisomerismo , Termodinâmica
15.
IEEE J Biomed Health Inform ; 27(11): 5622-5633, 2023 11.
Artigo em Inglês | MEDLINE | ID: mdl-37556336

RESUMO

Deep neural networks (DNNs) have successfully classified EEG-based brain-computer interface (BCI) systems. However, recent studies have found that well-designed input samples, known as adversarial examples, can easily fool well-performed deep neural networks model with minor perturbations undetectable by a human. This paper proposes an efficient generative model named generative perturbation network (GPN), which can generate universal adversarial examples with the same architecture for non-targeted and targeted attacks. Furthermore, the proposed model can be efficiently extended to conditionally or simultaneously generate perturbations for various targets and victim models. Our experimental evaluation demonstrates that perturbations generated by the proposed model outperform previous approaches for crafting signal-agnostic perturbations. We demonstrate that the extended network for signal-specific methods also significantly reduces generation time while performing similarly. The transferability across classification networks of the proposed method is superior to the other methods, which shows our perturbations' high level of generality.


Assuntos
Interfaces Cérebro-Computador , Humanos , Redes Neurais de Computação
16.
J Neurol Surg A Cent Eur Neurosurg ; 84(1): 37-43, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34897622

RESUMO

BACKGROUND AND STUDY OBJECT: Pedicle screw fixation has been widely used in surgical treatment for infective lumbar spondylodiskitis to prevent instability and deformity. The cortical bone trajectory pedicle screw (CBTPS) fixation is a minimally invasive posterior spinal fixation system that runs from the pedicle's entry point of the caudiomedial region toward the cephalad-divergent direction. Successful results with CBTPS fixation have been reported to treat degenerative and osteoporotic spinal diseases. This study aims to investigate the clinical feasibility of CBTPS in the surgical treatment of pyogenic lumbar spondylodiskitis. PATIENT AND METHODS: We retrospectively retrieved 20 consecutive patients from two academic centers who were surgically treated for monosegmental lumbar pyogenic spondylodiskitis. The primary surgical treatment was the anterior lumbar interbody fusion with decompression, debridement, and reconstruction using an autogenous iliac strut bone graft. One to 2 weeks after the primary surgery, patients underwent a second surgery for posterior instrumentation using conventional pedicle screws (CPS; group I) and CBTPS (group II). Radiographic parameters of the deformity angle at the fusion segment and clinical parameter of visual analog scale (VAS) scores were assessed preoperatively, postoperatively, and at the last follow-up. RESULTS: There were 10 patients in each group. The mean follow-up periods of groups I and II were 51.10 ± 6.95 and 28.60 ± 9.31 months, respectively. Intergroup analysis indicated the two groups area age-matched (p = 0.38), but initial C-reactive protein (CRP; mg/dL, p = 0.04), CRP normalization (months, p = 0.00), and follow-up duration (months, p = 0.00) were heterogeneous. Meanwhile, deformity angles (segmental lordosis) between the two groups were not significantly different preoperatively (p = 0.25), postoperatively (p = 0.13), and at last follow-up (p = 0.38). The intragroup analysis indicated a significant postoperative increase of lordosis in both group I and II (p = 0.00 and 0.04, respectively) with subsequent subsidence. Lordosis remained increased at the last follow-up with or without significance (group I, p = 0.02; group II, p = 0.62). Both groups showed significant improvement in VAS scores (group I, p = 0.00; group II, p = 0.00). CONCLUSION: In monosegmental lumbar spondylodiskitis, posterior stabilization of the anterior strut bone graft by CBTPS and CPS was comparable via the radiographic parameter of segmental lordosis or deformity angle. Our observation suggests the clinical feasibility of CBTPS in the treatment of relatively mild monosegmental pyogenic lumbar spondylodiskitis.


Assuntos
Discite , Lordose , Parafusos Pediculares , Fusão Vertebral , Humanos , Discite/diagnóstico por imagem , Discite/cirurgia , Estudos Retrospectivos , Vértebras Lombares/diagnóstico por imagem , Vértebras Lombares/cirurgia , Fusão Vertebral/métodos , Osso Cortical/diagnóstico por imagem , Osso Cortical/cirurgia , Resultado do Tratamento
17.
Poult Sci ; 102(4): 102498, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36739799

RESUMO

This study was conducted to investigate the effect of supplementing solubles from steam-exploded pine particles (SSPP) on mitigating the adverse effects of cyclic heat stress (CHS) in broilers which were distributed into 3 dietary treatment groups and 2 temperature conditions. Heat stress (HS) exposure for 6 h daily for 7 d adversely affected performance parameters and rectal temperature of chickens. The absolute and relative weights of the liver and bursa of Fabricius decreased in the CHS group while the relative lengths of the jejunum and ileum increased, which was rescued by dietary supplementation with SSPP. The expression of mucin2 (MUC2) and occludin (OCLN) genes was decreased in CHS birds. The expression of heat shock protein -70 and -90 increased in 0% HS compared to that in 0% NT. Birds supplemented with 0.4% SSPP had higher NADPH oxidase -1 expression than birds in the 0% and 0.1% SSPP treatments. Beta diversity of gut microbiota evaluated through unweighted UniFrac distances was significantly different among treatments. Bacteroidetes was among the 2 most abundant phyla in the cecum, which decreased with 0.1% NT and increased with 0.1% HS in comparison to 0% NT. A total of 13 genera were modified by HS, 5 were altered by dose, and nine showed an interaction effect. In conclusion, CHS adversely affects performance and gut health which can be mitigated with dietary SSPP supplementation that modifies the cecal microbiota in broilers.


Assuntos
Galinhas , Microbioma Gastrointestinal , Animais , Vapor , Suplementos Nutricionais , Dieta/veterinária , Resposta ao Choque Térmico , Ceco , Ração Animal/análise
18.
J Anim Sci Technol ; 65(5): 971-988, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37969336

RESUMO

This study evaluated the effects of supplementing solubles from shredded, steam-exploded pine particles (SSPP) on growth performances, plasma biochemicals, and microbial composition in broilers. The birds were reared for 28 days and fed basal diets with or without the inclusion of SSPP from 8 days old. There were a total of three dietary treatments supplemented with 0% (0% SSPP), 0.1% (0.1% SSPP) and 0.4% (0.4% SSPP) SSPP in basal diets. Supplementation of SSPP did not significantly affect growth or plasma biochemicals, but there was a clear indication of diet-induced microbial shifts. Beta-diversity analysis revealed SSPP supplementation-related clustering (ANOSIM: r = 0.31, p < 0.01), with an overall lower (PERMDISP: p < 0.05) individual dispersion in comparison to the control group. In addition, the proportions of the Bacteroides were increased, and the relative abundances of the families Vallitaleaceae, Defluviitaleaceae, Clostridiaceae, and the genera Butyricicoccus and Anaerofilum (p < 0.05) were significantly higher in the 0.4% SSPP group than in the control group. Furthermore, the linear discriminant analysis effect size (LEfSe) also showed that beneficial bacteria such as Ruminococcus albus and Butyricicoccus pullicaecorum were identified as microbial biomarkers of dietary SSPP inclusion (p < 0.05; | LDA effect size | > 2.0). Finally, network analysis showed that strong positive correlations were established among microbial species belonging to the class Clostridia, whereas Erysipelotrichia and Bacteroidia were mostly negatively correlated with Clostridia. Taken together, the results suggested that SSPP supplementation modulates the cecal microbial composition of broilers toward a "healthier" profile.

19.
ACS Appl Mater Interfaces ; 14(26): 30205-30215, 2022 Jul 06.
Artigo em Inglês | MEDLINE | ID: mdl-35737432

RESUMO

Over the past few years, considerable effort has been directed toward the development and improvement of mechanoluminescence (ML)-based stress sensing as an efficient nondestructive inspection technique. One of the challenges in ML stress sensing is the limited luminescent intensity and sensitivity of the ML-epoxy composite film to the local stress field. Herein, we present a novel approach for increasing the sensitivity of ML composites made of an epoxy resin matrix and SrAl2O4:Eu2+, Dy3+ particles functionalized with (3-aminopropyl)triethoxysilane. We performed a tensile test on an epoxy/ML composite specimen to investigate the effect of surface modification of ML particles on the luminescent sensitivity. A series of characterization analyses were performed on the modified surface to investigate the interfacial bonding. In addition, we applied the modified ML/epoxy paint to one side of the tensile specimen with an artificial invisible notch on the other side to visualize the stress field via light intensity (LI) distribution and then compared the results through a finite-element analysis (FEA). Surface modification of ML particles increased the sensitivity and introduced new chemical bonds, corresponding to a larger stress transfer through interfacial bonding rather than mere mechanical locking. In addition, the applied ML film on the notched specimen could visualize the specific pattern of LI reflecting the presence of a crack, which was confirmed by the FEA simulation. This implies that the proposed method of enhancing the ML film is promising for nondestructively predicting the presence, shape, and residual life of a crack in a specimen.

20.
Foods ; 11(14)2022 Jul 14.
Artigo em Inglês | MEDLINE | ID: mdl-35885336

RESUMO

Citrus peels are generally discarded as waste, although they are rich sources of health-promoting compounds. This study investigated the properties of citrus peels for development as a potential functional tea ingredient. Three citrus peel powders (DCPPs, Cheonhyehyang, Hallabong, and orange) which were dried by air- and freeze-drying, were used to prepare machine-drip tea. Then, total polyphenol compounds (TPCs), flavonoids, and the DPPH radical scavenging activity of DCPPs and teas were evaluated. Freeze-dried DCPPs had relatively higher TPC s (16.47-21.11 mg GAE/g) and DPPH radical scavenging activity (3.25-16.43 mg GAE/g) than air-dried DCPPs; TPCs (14.06-19.12 mg GAE/g) and DPPH radical scavenging activity (1.80-3.22 mg GAE/g). In contrast, air-dried DCPPs were more effective in machine-drip teas, showing a higher range of TPCs (50.64-85.12 mg GAE/100 mL) and DPPH radical scavenging activity (1.05-3.86 mg GAE/100 mL) than freeze-dried DCPPs; TPCs (40.44-46.69 mg GAE/100 mL) and DPPH radical scavenging activity (0.56-1.08 mg GAE/100 mL). Among citrus varieties, Cheonhyehyang had the highest TPCs and DPPH radical scavenging activity in both DCPP and tea. Four flavonoids (Hesperidin, Naringin, Nobiletin, and Tangeretin) mainly existed in citrus peels. The amount of hesperidin was highest; therefore, Hallabong and orange exhibited higher total flavonoid contents. However, freeze-dried Cheonhyehyang peel and air-dried Cheonhyehyang tea, which showed the highest TPCs and DPPH radical scavenging activity, had higher nobiletin and tangeretin. This implies that nobiletin and tangeretin strongly influenced the antioxidant activity of citrus peels with TPC. This research provides essential information for the tea industry looking for functional ingredients. In addition, it helps to reduce by-products by using citrus peel powders.

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