Detalhe da pesquisa
1.
The malate shuttle detoxifies ammonia in exhausted T cells by producing 2-ketoglutarate.
Nat Immunol
; 24(11): 1921-1932, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37813964
2.
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
Cell
; 182(5): 1252-1270.e34, 2020 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32818467
3.
Inhibition of fatty acid oxidation enables heart regeneration in adult mice.
Nature
; 622(7983): 619-626, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37758950
4.
Nα-acetyltransferase NAA50 mediates plant immunity independent of the Nα-acetyltransferase A complex.
Plant Physiol
; 2024 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38588051
5.
Mitochondrial dysfunction and oxidative stress contribute to cognitive and motor impairment in FOXP1 syndrome.
Proc Natl Acad Sci U S A
; 119(8)2022 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35165191
6.
Publisher Correction: Inhibition of fatty acid oxidation enables heart regeneration in adult mice.
Nature
; 623(7986): E7, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37863963
7.
Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation.
Nature
; 560(7718): E28, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30069041
8.
Histone deacetylase-10 liberates spermidine to support polyamine homeostasis and tumor cell growth.
J Biol Chem
; 298(10): 102407, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35988653
9.
FATP4 deletion in liver cells induces elevation of extracellular lipids via metabolic channeling towards triglycerides and lipolysis.
Biochem Biophys Res Commun
; 687: 149161, 2023 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37931418
10.
Increased circulating uric acid aggravates heart failure via impaired fatty acid metabolism.
J Transl Med
; 21(1): 199, 2023 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36927819
11.
Complex metabolic disharmony in PMM2-CDG paves the way to new therapeutic approaches.
Mol Genet Metab
; 139(3): 107610, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37245379
12.
Mitochondrial alternative NADH dehydrogenases NDA1 and NDA2 promote survival of reoxygenation stress in Arabidopsis by safeguarding photosynthesis and limiting ROS generation.
New Phytol
; 238(1): 96-112, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36464787
13.
BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation.
Nature
; 551(7680): 384-388, 2017 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29144447
14.
Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination.
Proc Natl Acad Sci U S A
; 117(1): 741-751, 2020 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31871212
15.
Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout.
J Am Chem Soc
; 144(41): 18861-18875, 2022 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36200994
16.
CD8 agonism functionally activates memory T cells and enhances antitumor immunity.
Int J Cancer
; 151(5): 797-808, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35499751
17.
The Metabolic Map into the Pathomechanism and Treatment of PGM1-CDG.
Am J Hum Genet
; 104(5): 835-846, 2019 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30982613
18.
Metabolic and inflammatory reprogramming of macrophages by ONC201 translates in a pro-inflammatory environment even in presence of glioblastoma cells.
Eur J Immunol
; 51(5): 1246-1261, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33442873
19.
The function of glutaredoxin GRXS15 is required for lipoyl-dependent dehydrogenases in mitochondria.
Plant Physiol
; 186(3): 1507-1525, 2021 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33856472
20.
Abrogating GPT2 in triple-negative breast cancer inhibits tumor growth and promotes autophagy.
Int J Cancer
; 148(8): 1993-2009, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33368291