Detalhe da pesquisa
1.
Communications and High-Precision Positioning (CHP2): Hardware Architecture, Implementation, and Validation.
Sensors (Basel)
; 23(3)2023 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36772385
2.
Discovery of IDO1 inhibitors containing a decahydroquinoline, decahydro-1,6-naphthyridine, or octahydro-1H-pyrrolo[3,2-c]pyridine scaffold.
Bioorg Med Chem Lett
; 49: 128314, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34391891
3.
SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors.
Bioorg Med Chem Lett
; 47: 128214, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34166782
4.
Diminishing GSH-Adduct Formation of Tricyclic Diazepine-based Mutant IDH1 Inhibitors.
ACS Med Chem Lett
; 13(4): 734-741, 2022 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35450359
5.
Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing.
J Med Chem
; 65(8): 6001-6016, 2022 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35239336
6.
Carbamate and N-Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors.
ACS Med Chem Lett
; 12(3): 389-396, 2021 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33738066
7.
Continuous Flow Enables Metallaphotoredox Catalysis in a Medicinal Chemistry Setting: Accelerated Optimization and Library Execution of a Reductive Coupling between Benzylic Chlorides and Aryl Bromides.
Org Lett
; 22(2): 410-416, 2020 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31880945
8.
Synthesis of Bridged Bicyclic Amines by Intramolecular Amination of Remote C-H Bonds: Synergistic Activation by Light and Heat.
Org Lett
; 22(16): 6578-6583, 2020 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32806157
9.
Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors.
ACS Med Chem Lett
; 11(8): 1548-1554, 2020 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32832022
10.
Strategic Incorporation of Polarity in Heme-Displacing Inhibitors of Indoleamine-2,3-dioxygenase-1 (IDO1).
ACS Med Chem Lett
; 11(4): 550-557, 2020 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32292563
11.
Discovery of N-(Indazol-3-yl)piperidine-4-carboxylic Acids as RORγt Allosteric Inhibitors for Autoimmune Diseases.
ACS Med Chem Lett
; 11(2): 114-119, 2020 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32071676
12.
Aryloxypyrazines as highly selective antagonists of Oxytocin.
Bioorg Med Chem Lett
; 19(10): 2634-6, 2009 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19376698
13.
Photoredox Ni-catalyzed peptide C(sp2)-O cross-coupling: from intermolecular reactions to side chain-to-tail macrocyclization.
Chem Sci
; 10(19): 5073-5078, 2019 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31183058
14.
Development of a Platform To Enable Efficient Permeability Evaluation of Novel Organo-Peptide Macrocycles.
ACS Med Chem Lett
; 10(6): 874-879, 2019 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31223441
15.
The NLRP3 inflammasome mediates DSS-induced intestinal inflammation in Nod2 knockout mice.
Innate Immun
; 25(2): 132-143, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30774010
16.
Discovery of Amino-cyclobutarene-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors for Cancer Immunotherapy.
ACS Med Chem Lett
; 10(11): 1530-1536, 2019 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31749906
17.
Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity Profiles.
J Med Chem
; 60(16): 6771-6780, 2017 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28418656
18.
Synthesis of Cyclic Peptidomimetics via a Pd-Catalyzed Macroamination Reaction.
Org Lett
; 18(16): 4072-5, 2016 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27508926
19.
Identification of a chemical probe for bromo and extra C-terminal bromodomain inhibition through optimization of a fragment-derived hit.
J Med Chem
; 55(22): 9831-7, 2012 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23095041
20.
Decarboxylative biaryl synthesis in a continuous flow reactor.
Chem Commun (Camb)
; 47(12): 3628-30, 2011 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21301726