Detalhe da pesquisa
1.
A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses.
PLoS Biol
; 17(6): e3000281, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31185007
2.
A short survey of dengue protease inhibitor development in the past 6 years (2015-2020) with an emphasis on similarities between DENV and SARS-CoV-2 proteases.
Bioorg Med Chem
; 49: 116415, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34601454
3.
Quinazolinone derivative BNUA-3 ameliorated [NDEA+2-AAF]-induced liver carcinogenesis in SD rats by modulating AhR-CYP1B1-Nrf2-Keap1 pathway.
Clin Exp Pharmacol Physiol
; 47(1): 143-157, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31563143
4.
Design, synthesis, optimization and antiviral activity of a class of hybrid dengue virus E protein inhibitors.
Bioorg Med Chem Lett
; 25(8): 1747-1752, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25791449
5.
Synthesis and molecular modelling studies of novel sulphonamide derivatives as dengue virus 2 protease inhibitors.
Bioorg Chem
; 62: 74-82, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26247308
6.
A rapid and sensitive determination of hypoxic radiosensitizer agent nimorazole in rat plasma by LC-MS/MS and its application to a pharmacokinetic study.
Biomed Chromatogr
; 29(10): 1575-80, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25845449
7.
Effect of substitution at Nâ³-position of N'-hydroxy-N-amino guanidines on tumor cell growth.
Bioorg Med Chem Lett
; 22(15): 4934-8, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22781189
8.
A Critical Observation on the Design and Development of Reported Peptide Inhibitors of DENV NS2B-NS3 Protease in the Last Two Decades.
Mini Rev Med Chem
; 22(8): 1108-1130, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34720077
9.
Mycobactin Analogues with Excellent Pharmacokinetic Profile Demonstrate Potent Antitubercular Specific Activity and Exceptional Efflux Pump Inhibition.
J Med Chem
; 65(1): 234-256, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34981940
10.
Pyrazoline based MAO inhibitors: synthesis, biological evaluation and SAR studies.
Bioorg Med Chem Lett
; 21(14): 4296-300, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21680183
11.
Two new anticancer phenolic derivatives from leaves of Piper betle Linn.
Nat Prod Res
; 35(23): 5021-5029, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32375527
12.
The Mycobactin Biosynthesis Pathway: A Prospective Therapeutic Target in the Battle against Tuberculosis.
J Med Chem
; 64(1): 71-100, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33372516
13.
Design, synthesis and anticancer activity of piperazine hydroxamates and their histone deacetylase (HDAC) inhibitory activity.
Bioorg Med Chem Lett
; 20(13): 3906-10, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20605448
14.
Development of selective and reversible pyrazoline based MAO-A inhibitors: Synthesis, biological evaluation and docking studies.
Bioorg Med Chem
; 18(5): 1875-81, 2010 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20149663
15.
Inhibitors of human histone deacetylase: synthesis and enzyme assay of hydroxamates with piperazine linker.
Arch Pharm (Weinheim)
; 343(3): 167-72, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20217840
16.
The new ether derivative of phenylpropanoid and bioactivity was investigated from the leaves of Piper betle L.
Nat Prod Res
; 34(5): 638-645, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30169967
17.
Scaffold Based Search on the Desferithiocin Archetype.
Mini Rev Med Chem
; 19(19): 1564-1576, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30827237
18.
Phytoestrogens and their synthetic analogues as substrate mimic inhibitors of CYP1B1.
Eur J Med Chem
; 163: 28-36, 2019 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30503941
19.
Cink4T, a quinazolinone-based dual inhibitor of Cdk4 and tubulin polymerization, identified via ligand-based virtual screening, for efficient anticancer therapy.
Eur J Med Chem
; 165: 115-132, 2019 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30665142
20.
New chemical constituents from the Piper betle Linn. (Piperaceae).
Nat Prod Res
; 32(9): 1080-1087, 2018 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28978254