Detalhe da pesquisa
1.
Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution.
Proc Natl Acad Sci U S A
; 120(35): e2302070120, 2023 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37603745
2.
Hyphal-associated protein expression is crucial for Candida albicans-induced eicosanoid biosynthesis in immune cells.
Eur J Immunol
; 54(3): e2350743, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38233139
3.
Mycobacterium tuberculosis-Induced Prostaglandin J2 and 15-Deoxy-Prostaglandin J2 Inhibit Inflammatory Signals in Human M1 Macrophages via a Negative Feedback Loop.
J Immunol
; 210(10): 1564-1575, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37042680
4.
Arachidonic acid-derived lipid mediators in multiple sclerosis pathogenesis: fueling or dampening disease progression?
J Neuroinflammation
; 21(1): 21, 2024 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38233951
5.
Novel 1,3,4-oxadiazole derivatives as highly potent microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors.
Bioorg Chem
; 147: 107383, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38653151
6.
Structure Revision of a Widespread Marine Sulfonolipid Class Based on Isolation and Total Synthesis.
Angew Chem Int Ed Engl
; : e202401195, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38529534
7.
A Thromboxane A2 Receptor-Driven COX-2-Dependent Feedback Loop That Affects Endothelial Homeostasis and Angiogenesis.
Arterioscler Thromb Vasc Biol
; 42(4): 444-461, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35236104
8.
Synthesis and biological evaluation of simplified ajudazol derivatives reveal potent 5-lipoxygenase inhibition and considerable apoptotic activity in neuroblastoma cells.
Bioorg Med Chem Lett
; 94: 129464, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37634760
9.
Novel thiazolopyridine derivatives of diflapolin as dual sEH/FLAP inhibitors with improved solubility.
Bioorg Chem
; 139: 106685, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37418786
10.
Mediterranean diet component oleic acid increases protective lipid mediators and improves trabecular bone in a Porphyromonas gingivalis inoculation model.
J Clin Periodontol
; 50(3): 380-395, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36384158
11.
Label-Free Characterization of Macrophage Polarization Using Raman Spectroscopy.
Int J Mol Sci
; 24(1)2023 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36614272
12.
Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A4 Hydrolase.
Int J Mol Sci
; 24(8)2023 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37108702
13.
α-Tocopherol-13'-Carboxychromanol Induces Cell Cycle Arrest and Cell Death by Inhibiting the SREBP1-SCD1 Axis and Causing Imbalance in Lipid Desaturation.
Int J Mol Sci
; 24(11)2023 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37298183
14.
Establishment and Characterization of Mild Atopic Dermatitis in the DNCB-Induced Mouse Model.
Int J Mol Sci
; 24(15)2023 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37569701
15.
Comparison of gastrointestinal adverse events between fast release tablets and regular acetylsalicylic acid (aspirin) galenics after short-term use: a meta-analysis of randomized clinical trials.
Inflammopharmacology
; 31(5): 2369-2381, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37603157
16.
Staphylococcus aureus controls eicosanoid and specialized pro-resolving mediator production via lipoteichoic acid.
Immunology
; 166(1): 47-67, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35143048
17.
Synthesis of Functionalized δ-Hydroxy-ß-keto Esters and Evaluation of Their Anti-inflammatory Properties.
Chembiochem
; 23(9): e202200073, 2022 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35244320
18.
SARS-CoV-2 causes severe epithelial inflammation and barrier dysfunction.
J Virol
; 95(10)2021 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33637603
19.
Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products.
Nat Chem Biol
; 16(7): 783-790, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393899
20.
Candida albicans-induced leukotriene biosynthesis in neutrophils is restricted to the hyphal morphology.
FASEB J
; 35(10): e21820, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34569657