Detalhe da pesquisa
1.
α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming.
Nat Immunol
; 18(9): 985-994, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28714978
2.
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity.
Nature
; 566(7744): 403-406, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30728499
3.
Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite-binding site.
J Biol Chem
; 298(5): 101852, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35331736
4.
Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation.
Mol Cell
; 57(1): 95-107, 2015 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25482511
5.
AMPK promotes survival of c-Myc-positive melanoma cells by suppressing oxidative stress.
EMBO J
; 37(5)2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29440228
6.
Fatty acid carbon is essential for dNTP synthesis in endothelial cells.
Nature
; 520(7546): 192-197, 2015 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25830893
7.
A Method to Monitor the NAD+ Metabolome-From Mechanistic to Clinical Applications.
Int J Mol Sci
; 22(19)2021 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34638936
8.
Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells.
Diabetologia
; 63(12): 2628-2640, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32960311
9.
Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.
Proc Natl Acad Sci U S A
; 113(7): 1778-83, 2016 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26831078
10.
Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors.
Metab Eng
; 43(Pt B): 187-197, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27847310
11.
Reduction of falls and fractures after permanent pacemaker implantation in elderly patients with sinus node dysfunction.
Europace
; 19(7): 1220-1226, 2017 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27702858
12.
Inferring causal metabolic signals that regulate the dynamic TORC1-dependent transcriptome.
Mol Syst Biol
; 11(4): 802, 2015 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25888284
13.
Metabolic control of signalling pathways and metabolic auto-regulation.
Biol Cell
; 107(8): 251-72, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25913226
14.
Corrigendum: Fatty acid carbon is essential for dNTP synthesis in endothelial cells.
Nature
; 526(7571): 144, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26245368
15.
Organ-Specific Cancer Metabolism and Its Potential for Therapy.
Handb Exp Pharmacol
; 233: 321-53, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-25912014
16.
Local requirement of the Drosophila insulin binding protein imp-L2 in coordinating developmental progression with nutritional conditions.
Dev Biol
; 381(1): 97-106, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23773803
17.
mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism.
Nat Commun
; 15(1): 4083, 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38744825
18.
Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia.
Nat Metab
; 6(3): 433-447, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38504132
19.
PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma.
Oncogenesis
; 11(1): 57, 2022 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36115843
20.
Unraveling condition-dependent networks of transcription factors that control metabolic pathway activity in yeast.
Mol Syst Biol
; 6: 432, 2010 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21119627