Benefits of music therapy on behaviour disorders in subjects diagnosed with dementia: a systematic review. / Beneficios de la musicoterapia en las alteraciones conductuales de la demencia. Revisión sistemática.

INTRODUCTION: Dementia is characterised by cognitive deterioration and the manifestation of psychological and behavioural symptoms, especially changes in perception, thought content, mood, and conduct. In addition to drug therapy, non-pharmacological treatments are used to manage these symptoms, and one of these latter treatments is music therapy. Since this novel technique in non-verbal, it can be used to treat patients with dementia at any stage, even when cognitive deterioration is very severe. Patients' responses to music are conserved even in the most advanced stages of the disease DEVELOPMENT: A literature research was carried out using the following databases: Academic Search Complete, PubMed, Science Direct y Dialnet. The period of publication was 2003 to 2013 and the search keywords were 'Music Therapy, Dementia, Behaviour, Behaviour Disorders y Behavioural Disturbances'. Out of the 2188 studies that were identified, 11 studies met inclusion criteria for the systematic review. CONCLUSIONS: Music therapy is beneficial and improves behavior disorders, anxiety and agitation in subjects diagnosed with dementia.

Molecular signatures of atherosclerotic plaques: An up-dated panel of protein related markers.

Atherosclerosis remains the leading cause of ischemic syndromes such as myocardial infarction or brain stroke, mainly promoted by plaque rupture and subsequent arterial blockade. Identification of vulnerable or high-risk plaques constitutes a major challenge, being necessary to identify patients at risk of occlusive events in order to provide them with appropriate therapies. Clinical imaging tools have allowed the identification of certain structural indicators of prone-rupture plaques, including a necrotic lipidic core, intimal and adventitial inflammation, extracellular matrix dysregulation, and smooth muscle cell depletion and micro-calcification. Additionally, alternative approaches focused on identifying molecular biomarkers of atherosclerosis have also been applied. Among them, proteomics has provided numerous protein markers currently investigated in clinical practice. In this regard, it is quite uncertain that a single molecule can describe plaque rupture, due to the complexity of the process itself. Therefore, it should be more accurate to consider a set of markers to define plaques at risk. Herein, we propose a selection of 76 proteins, from classical inflammatory to recently related markers, all of them identified in at least two proteomic studies analyzing unstable atherosclerotic plaques. Such panel could be used as a prognostic signature of plaque instability.

Beneficios de la musicoterapia en las alteraciones conductuales de la demencia. Revisión sistemática / Benefits of music therapy on behaviour disorders in subjects diagnosed with dementia: a systematic review

Introducción. La demencia se caracteriza por un deterioro cognitivo y por la aparición de síntomas psicológicos y conductuales, entre los que destacan las alteraciones de percepción, del contenido del pensamiento, estado de ánimo y de conducta. Para tratar estos síntomas, además del tratamiento farmacológico, se utilizan intervenciones no farmacológicas, entre ellas la musicoterapia. Esta técnica novedosa, por sus características no verbales, puede ser usada en todas las fases del tratamiento de las personas con demencia ya que, aunque haya un gran deterioro cognitivo, las respuestas ante la música se mantienen hasta los estadios más avanzados de la enfermedad. Desarrollo. Se realizó una búsqueda bibliográfica con un intervalo temporal entre 2003 y 2013 en las bases de datos Academic Search Complete, PubMed, Science Direct y Dialnet. Los términos de búsqueda incluyeron la combinación de las palabras claves «music therapy, dementia, behaviour, behavioural disorders y behavioural disturbances». Se seleccionaron 11 registros de los 2188 localizados tras aplicar los criterios de inclusión. Conclusiones. El tratamiento con musicoterapia es beneficioso para mejorar las alteraciones conductuales, la ansiedad y la agitación en pacientes con demencia (AU)

Introduction. Dementia is characterised by cognitive deterioration and the manifestation of psychological and behavioural symptoms, especially changes in perception, thought content, mood, and conduct. In addition to drug therapy, non-pharmacological treatments are used to manage these symptoms, and one of these latter treatments is music therapy. Since this novel technique in non-verbal, it can be used to treat patients with dementia at any stage, even when cognitive deterioration is very severe. Patients’ responses to music are conserved even in the most advanced stages of the disease Development. A literature research was carried out using the following databases: Academic Search Complete, PubMed, Science Direct y Dialnet. The period of publication was 2003 to 2013 and the search keywords were «Music Therapy, Dementia, Behaviour, Behaviour Disorders y Behavioural Disturbances». Out of the 2188 studies that were identified, 11 studies met inclusion criteria for the systematic review. Conclusions. Music therapy is beneficial and improves behavior disorders, anxiety and agitation in subjects diagnosed with dementia (AU)

Efectividad de la terapia asistida con animales en pacientes con demencias, una revisión sistemática / Effectiveness of animal-assisted therapy in patients with dementia: A systematic review

Objetivo: Sintetizar la efectividad presentada por estudios originales previos de la terapia asistida con animales en la sintomatología de personas con demencia. Material y métodos: Se desarrolló una estrategia de búsqueda en las bases de datos PUBMED, DIALNET, PEDro y CSIC con el fin de captar todos aquellos ensayos clínicos publicados entre 2003 y 2015 en inglés y español. Los términos de búsqueda incluyeron la combinación de las palabras clave: «dog therapy, dementia, pet therapy, mental illnes, animal assisted, ederly patients, animal assisted therapy, terapia asistida con animales, demencia, Alzheimer». Se seleccionaron 3 registros de los 157 localizados tras aplicar los criterios de inclusión. Conclusiones: La terapia más utilizada a la hora de llevar a cabo terapia asistida con animales en demencia es la canina. Esta terapia produce una mejora en el comportamiento, estado de ánimo, calidad de vida, actividades de la vida diaria y en el estrés mental de personas que padecen demencia

Objective: To analyse the effectiveness of animal-assisted therapy on the symptoms of dementia as shown in previous studies. Material and methods: A search strategy was developed using the PUBMED, DIALNET, PEDro and CSIC databases to capture all clinical trials published between 2003 and 2015 in English and Spanish. Search terms included the combination of the keywords: 'dog therapy, dementia, pet therapy, mental illness, animal assisted, elderly patients, animal assisted therapy, animal assisted therapy, dementia, Alzheimer's.' Three records were selected from the 157 located after applying the inclusion criteria. Conclusions: The dog is the most commonly used in animal-assisted therapy in dementia. This therapy produces an improvement in behaviour, mood, quality of life, activities of daily living, and mental stress of people with dementia

Escalas utilizadas para valorar el dolor en niños de 0-24 meses tras una intervención quirúrgica menor. Instrumentos de ayuda para la valoración en fisioterapia / Scales used to evaluate pain in infants aged 0-24 months after minor surgery. Instruments for help in physiotherapy evaluation

ObjetivoConocer, con base en los estudios publicados recientemente, el tipo de escalas que están siendo utilizadas para evaluar el dolor en niños.Búsqueda y selección de estudiosSe identificaron 75 publicaciones mediante la búsqueda electrónica en las bases de datos MEDLINE, ISI of Knowledge, Dialnet, Cochrane Library Plus y PEDro. Los criterios de inclusión fueron artículos en inglés o español publicados desde enero de 1995 hasta enero de 2012 que incluían escalas para evaluar el dolor de sujetos de hasta 24 meses de edad después de una intervención quirúrgica menor. Como criterio de exclusión se establecieron estudios que hacían referencia a sujetos con edades no comprendidas en el intervalo de edad estudiado.ResultadosSe incluyeron 4 estudios en la revisión con calidad metodológica variable y heterogeneidad en el tamaño de la muestra. Sus autores utilizan distintas escalas observacionales que muestran datos positivos con respecto a la detección del dolor.ConclusionesEs necesario un mayor número de estudios para determinar las escalas más utilizadas en la valoración del dolor en niños de hasta 24 meses de edad tras una intervención quirúrgica menor. Parece ser que la utilización de escalas observacionales puede detectar el dolor en esta tipología de pacientes(AU)

ObjectiveTo know, based on the most recent studies published, the scales that are being used to evaluate pain in infants.Search and study selectionSeventy-five publications were identified by electronic search using the databases MEDLINE, ISI of Knowledge, Dialnet, Cochrane Library Plus and PEDro. Inclusion criteria were articles published from January 1995 to January 2012 in English or Spanish that included scales to assess pain after minor surgery in infants of 0-24 months. Exclusion criteria established were articles on any other type of patients not included in the established age range.ResultsFour articles with variable methodological quality and sample size heterogeneity were included. Their authors used different observational scales that show positive data for pain detection.ConclusionsMore studies are needed to determine the scales used most in the evaluation of pain in infants from 0 to 24 months after minor surgery. It seems that the use of observational scales may detect pain in this type of patients (AU)