Detalhe da pesquisa
1.
Oncometabolites suppress DNA repair by disrupting local chromatin signalling.
Nature
; 582(7813): 586-591, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32494005
2.
A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin.
Genes Dev
; 30(14): 1645-57, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27474442
3.
Polymer nanocarriers for targeted local delivery of agents in treating brain tumors.
Nanotechnology
; 34(7)2022 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36179653
4.
The Role of PARP Inhibitors in Patients with Primary Malignant Central Nervous System Tumors.
Curr Treat Options Oncol
; 23(11): 1566-1589, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36242713
5.
Brain Distribution of Berzosertib: An Ataxia Telangiectasia and Rad3-Related Protein Inhibitor for the Treatment of Glioblastoma.
J Pharmacol Exp Ther
; 379(3): 343-357, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34556535
6.
Estimation of the carrier frequency of fumarate hydratase alterations and implications for kidney cancer risk in hereditary leiomyomatosis and renal cancer.
Cancer
; 126(16): 3657-3666, 2020 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32413184
7.
Targeting DNA repair in gliomas.
Curr Opin Neurol
; 32(6): 878-885, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31592790
8.
Angiotensin receptor blockade: a novel approach for symptomatic radiation necrosis after stereotactic radiosurgery.
J Neurooncol
; 136(2): 289-298, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29124649
9.
Metastatic and multiply relapsed SDH-deficient GIST and paraganglioma displays clinical response to combined poly ADP-ribose polymerase inhibition and temozolomide.
Pediatr Blood Cancer
; 70(3): e30020, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36151992
10.
Response to the BRAF/MEK inhibitors dabrafenib/trametinib in an adolescent with a BRAF V600E mutated anaplastic ganglioglioma intolerant to vemurafenib.
Pediatr Blood Cancer
; 65(5): e26969, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29380516
11.
The role of radiation in treating glioblastoma: here to stay.
J Neurooncol
; 134(3): 479-485, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28271281
12.
GBM radiosensitizers: dead in the water or just the beginning?
J Neurooncol
; 134(3): 513-521, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28762004
13.
Characterization of Cardiac Glycoside Natural Products as Potent Inhibitors of DNA Double-Strand Break Repair by a Whole-Cell Double Immunofluorescence Assay.
J Am Chem Soc
; 138(11): 3844-55, 2016 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26927829
14.
Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells.
Nucleic Acids Res
; 41(11): e115, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23585275
15.
Introduction to the Yale Precision Medicine Tumor Board.
Lancet Oncol
; 19(1): 19-20, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29304351
16.
Yale Cancer Center Precision Medicine Tumor Board: two patients, one targeted therapy, different outcomes.
Lancet Oncol
; 19(1): 23-24, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29304353
17.
Exploiting Metabolic Defects in Glioma with Nanoparticle Encapsulated NAMPT Inhibitors.
Mol Cancer Ther
; 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38691846
18.
DNA damage response in brain tumors: A Society for Neuro-Oncology consensus review on mechanisms and translational efforts in neuro-oncology.
Neuro Oncol
; 2024 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38770568
19.
Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130.
Proc Natl Acad Sci U S A
; 107(5): 2201-6, 2010 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20133863
20.
Impact of radiotherapy delay following biopsy for patients with unresected glioblastoma.
J Neurosurg
; 138(3): 610-620, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35907197