Detalhe da pesquisa
1.
Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade.
Immunity
; 53(6): 1215-1229.e8, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33220234
2.
Study of the mechanisms of crocetin-induced differentiation and apoptosis in human acute promyelocytic leukemia cells.
J Cell Biochem
; 120(2): 1943-1957, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30203596
3.
Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing.
Hum Mol Genet
; 24(3): 828-40, 2015 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25274775
4.
Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks.
Hum Mol Genet
; 19(7): 1324-34, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20064923
5.
Chemotherapy-induced COX-2 upregulation by cancer cells defines their inflammatory properties and limits the efficacy of chemoimmunotherapy combinations.
Nat Commun
; 13(1): 2063, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35440553
6.
Anti-Inflammatory Drugs Remodel the Tumor Immune Environment to Enhance Immune Checkpoint Blockade Efficacy.
Cancer Discov
; 11(10): 2602-2619, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34031121
7.
TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts.
Nat Commun
; 11(1): 1274, 2020 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152270
8.
Studying TDP1 Function in DNA Repair.
Methods Mol Biol
; 1703: 173-181, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29177742
9.
UVA-induced carbon-centred radicals in lightly pigmented cells detected using ESR spectroscopy.
Free Radic Biol Med
; 126: 153-165, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30055236
10.
UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis.
Cell Rep
; 23(11): 3352-3365, 2018 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29898404
11.
Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage.
Sci Adv
; 3(4): e1602506, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28508041
12.
C9orf72 expansion disrupts ATM-mediated chromosomal break repair.
Nat Neurosci
; 20(9): 1225-1235, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28714954
13.
A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN.
Cell Rep
; 15(4): 893-908, 2016 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27149854
14.
ATM deficiency results in accumulation of DNA-topoisomerase I covalent intermediates in neural cells.
PLoS One
; 8(4): e58239, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23626666
15.
SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair.
Nat Commun
; 3: 733, 2012 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22415824
16.
Identification and characterisation of the BPI/LBP/PLUNC-like gene repertoire in chickens reveals the absence of a LBP gene.
Dev Comp Immunol
; 35(3): 285-95, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20959152
17.
TDP1 serine 81 promotes interaction with DNA ligase IIIalpha and facilitates cell survival following DNA damage.
Cell Cycle
; 9(3): 588-595, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20009512