Detalhe da pesquisa
1.
Design, synthesis, and antiprotozoal evaluation of new 2,4-bis[(substituted-aminomethyl)phenyl]quinoline, 1,3-bis[(substituted-aminomethyl)phenyl]isoquinoline and 2,4-bis[(substituted-aminomethyl)phenyl]quinazoline derivatives.
J Enzyme Inhib Med Chem
; 35(1): 432-459, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31899980
2.
Improving Aqueous Solubility and In Vitro Pharmacokinetic Properties of the 3-Nitroimidazo[1,2-a]pyridine Antileishmanial Pharmacophore.
Pharmaceuticals (Basel)
; 15(8)2022 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36015146
3.
Design, Synthesis, and Antiprotozoal Evaluation of New Promising 2,9-Bis[(substituted-aminomethyl)]-4,7-phenyl-1,10-phenanthroline Derivatives, a Potential Alternative Scaffold to Drug Efflux.
Pathogens
; 11(11)2022 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36422591
4.
Microsatellite analysis of Fasciola spp. in Egypt.
Parasitol Res
; 109(6): 1741-4, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21744021
5.
New 8-Nitroquinolinone Derivative Displaying Submicromolar in Vitro Activities against Both Trypanosoma brucei and cruzi.
ACS Med Chem Lett
; 11(4): 464-472, 2020 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32292551
6.
Antikinetoplastid SAR study in 3-nitroimidazopyridine series: Identification of a novel non-genotoxic and potent anti-T. b. brucei hit-compound with improved pharmacokinetic properties.
Eur J Med Chem
; 206: 112668, 2020 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32795774
7.
8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi.
Eur J Med Chem
; 202: 112558, 2020 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32652409
8.
Increased CXCL-13 levels in human African trypanosomiasis meningo-encephalitis.
Trop Med Int Health
; 14(5): 529-34, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19298637
9.
Toxoplasma gondii Modulates the Host Cell Responses: An Overview of Apoptosis Pathways.
Biomed Res Int
; 2019: 6152489, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31080827
10.
Proteome characterization in various biological fluids of Trypanosoma brucei gambiense-infected subjects.
J Proteomics
; 196: 150-161, 2019 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30414516
11.
Using detergent-enhanced LAMP for African trypanosome detection in human cerebrospinal fluid and implications for disease staging.
PLoS Negl Trop Dis
; 13(8): e0007631, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31425540
12.
Neopterin and CXCL-13 in Diagnosis and Follow-Up of Trypanosoma brucei gambiense Sleeping Sickness: Lessons from the Field in Angola.
Biomed Res Int
; 2019: 6070176, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31886231
13.
Nongenotoxic 3-Nitroimidazo[1,2-a]pyridines Are NTR1 Substrates That Display Potent in Vitro Antileishmanial Activity.
ACS Med Chem Lett
; 10(1): 34-39, 2019 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30655943
14.
Antitrypanosomatid Pharmacomodulation at Position 3 of the 8-Nitroquinolin-2(1H)-one Scaffold Using Palladium-Catalysed Cross-Coupling Reactions.
ChemMedChem
; 13(20): 2217-2228, 2018 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30221468
15.
8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases.
Eur J Med Chem
; 157: 115-126, 2018 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30092366
16.
Design, synthesis, and antiprotozoal evaluation of new 2,9-bis[(substituted-aminomethyl)phenyl]-1,10-phenanthroline derivatives.
Chem Biol Drug Des
; 91(5): 974-995, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29266861
17.
Novel 8-nitroquinolin-2(1H)-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study.
Eur J Med Chem
; 155: 135-152, 2018 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29885575
18.
A link between chemokine levels and disease severity in human African trypanosomiasis.
Int J Parasitol
; 36(9): 1057-65, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16765963
19.
Metabolomics Identifies Multiple Candidate Biomarkers to Diagnose and Stage Human African Trypanosomiasis.
PLoS Negl Trop Dis
; 10(12): e0005140, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27941966
20.
Endothelial cell activation in the presence of African trypanosomes.
Mol Biochem Parasitol
; 139(1): 41-9, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15610818