Detalhe da pesquisa
1.
Modelling ASthma TrEatment Responses (MASTER): Effect of individual patient characteristics on the risk of exacerbation in moderate or severe asthma: A time-to-event analysis of randomized clinical trials.
Br J Clin Pharmacol
; 89(11): 3273-3290, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37221636
2.
Clinical trial diversity: An opportunity for improved insight into the determinants of variability in drug response.
Br J Clin Pharmacol
; 88(6): 2700-2717, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35088432
3.
Characterisation of individual ferritin response in patients receiving chelation therapy.
Br J Clin Pharmacol
; 88(8): 3683-3694, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35199367
4.
Impact of early vs. delayed initiation of dutasteride/tamsulosin combination therapy on the risk of acute urinary retention or BPH-related surgery in LUTS/BPH patients with moderate-to-severe symptoms at risk of disease progression.
World J Urol
; 39(7): 2635-2643, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-33337513
5.
Evaluation of pharmacokinetic-pharmacodynamic relationships and selection of drug combinations for tuberculosis.
Br J Clin Pharmacol
; 87(1): 140-151, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32415743
6.
Population pharmacokinetics of raxibacumab in healthy adult subjects.
Br J Clin Pharmacol
; 87(12): 4718-4725, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33973655
7.
Extrapolation and dosing recommendations for raxibacumab in children from birth to age <18 years.
Br J Clin Pharmacol
; 87(12): 4709-4717, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33974281
8.
Model-based meta-analysis of the time to first acute urinary retention or benign prostatic hyperplasia-related surgery in patients with moderate or severe symptoms.
Br J Clin Pharmacol
; 87(7): 2777-2789, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33247951
9.
Impact of disease progression on individual IPSS trajectories and consequences of immediate versus delayed start of treatment in patients with moderate or severe LUTS associated with BPH.
World J Urol
; 38(2): 463-472, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31079189
10.
Model-based meta-analysis of individual International Prostate Symptom Score trajectories in patients with benign prostatic hyperplasia with moderate or severe symptoms.
Br J Clin Pharmacol
; 86(8): 1585-1599, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32144791
11.
How long will treatment guidelines for TB continue to overlook variability in drug exposure?
J Antimicrob Chemother
; 74(11): 3274-3280, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31360999
12.
Can phenotypic data complement our understanding of antimycobacterial effects for drug combinations?
J Antimicrob Chemother
; 74(12): 3530-3536, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31504558
13.
Drug repurposing in neurological diseases: an integrated approach to reduce trial and error.
J Neurol Neurosurg Psychiatry
; 90(11): 1270-1275, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31171583
14.
Dose rationale and pharmacokinetics of dexmedetomidine in mechanically ventilated new-borns: impact of design optimisation.
Eur J Clin Pharmacol
; 75(10): 1393-1404, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31312867
15.
Pharmacokinetic interactions and dosing rationale for antiepileptic drugs in adults and children.
Br J Clin Pharmacol
; 84(1): 97-111, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28815754
16.
Dose optimization of piperacillin/tazobactam in critically ill children.
J Antimicrob Chemother
; 72(7): 2002-2011, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28387840
17.
Prediction of thyroid C-cell carcinogenicity after chronic administration of GLP1-R agonists in rodents.
Toxicol Appl Pharmacol
; 320: 51-59, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28213092
18.
Translating QT interval prolongation from conscious dogs to humans.
Br J Clin Pharmacol
; 83(2): 349-362, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27614058
19.
Population pharmacokinetics and dosing recommendations for the use of deferiprone in children younger than 6 years.
Br J Clin Pharmacol
; 83(3): 593-602, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27641003
20.
Pharmacology-based toxicity assessment: towards quantitative risk prediction in humans.
Mutagenesis
; 31(3): 359-74, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26970519