Detalhe da pesquisa
1.
A mechanism for oxidative damage repair at gene regulatory elements.
Nature
; 609(7929): 1038-1047, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36171374
2.
Choose your yeast strain carefully: the RAD5 gene matters.
Nat Rev Mol Cell Biol
; 19(6): 343-344, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29615784
3.
Nanomedicines targeting the inflammasome as a promising therapeutic approach for cell senescence.
Semin Cancer Biol
; 86(Pt 2): 46-53, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36030027
4.
Defective repair of topoisomerase I induced chromosomal damage in Huntington's disease.
Cell Mol Life Sci
; 79(3): 160, 2022 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35224690
5.
CORM-3 induces DNA damage through Ru(II) binding to DNA.
Biochem J
; 479(13): 1429-1439, 2022 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35726678
6.
DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity.
Cell Mol Life Sci
; 78(15): 5707-5729, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34173837
7.
Rad5, HLTF, and SHPRH: A Fresh View of an Old Story.
Trends Genet
; 34(8): 574-577, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29807746
8.
DNA Homeostasis and Senescence: Lessons from the Naked Mole Rat.
Int J Mol Sci
; 22(11)2021 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34199458
9.
Study of the mechanisms of crocetin-induced differentiation and apoptosis in human acute promyelocytic leukemia cells.
J Cell Biochem
; 120(2): 1943-1957, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30203596
10.
Perturbed autophagy and DNA repair converge to promote neurodegeneration in amyotrophic lateral sclerosis and dementia.
Brain
; 141(5): 1247-1262, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29584802
11.
Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan.
Nucleic Acids Res
; 45(3): 1159-1176, 2017 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28180300
12.
Competing endogenous RNA network crosstalk reveals novel molecular markers in colorectal cancer.
J Cell Biochem
; 119(8): 6869-6881, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29737552
13.
Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing.
Hum Mol Genet
; 24(3): 828-40, 2015 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25274775
14.
Role of Protein Linked DNA Breaks in Cancer.
Adv Exp Med Biol
; 1007: 41-58, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28840551
15.
Personalised Medicine: Genome Maintenance Lessons Learned from Studies in Yeast as a Model Organism.
Adv Exp Med Biol
; 1007: 157-178, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28840557
16.
TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy.
Nucleic Acids Res
; 42(5): 3089-103, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24335147
17.
A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage.
Nature
; 461(7264): 674-8, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19794497
18.
Development of an oligonucleotide-based fluorescence assay for the identification of tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors.
Anal Biochem
; 454: 17-22, 2014 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24637157
19.
TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.
Nucleic Acids Res
; 40(17): 8371-80, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22740648
20.
Chromosomal single-strand break repair and neurological disease: Implications on transcription and emerging genomic tools.
DNA Repair (Amst)
; 135: 103629, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38266593