Detalhe da pesquisa
1.
Clinical evaluation of the potential drug-drug interactions of savolitinib: Interaction with rifampicin, itraconazole, famotidine or midazolam.
Br J Clin Pharmacol
; 88(2): 655-668, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34322894
2.
Osimertinib plus savolitinib in patients with EGFR mutation-positive, MET-amplified, non-small-cell lung cancer after progression on EGFR tyrosine kinase inhibitors: interim results from a multicentre, open-label, phase 1b study.
Lancet Oncol
; 21(3): 373-386, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32027846
3.
AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer.
N Engl J Med
; 372(18): 1689-99, 2015 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25923549
4.
Metabolic Disposition of Osimertinib in Rats, Dogs, and Humans: Insights into a Drug Designed to Bind Covalently to a Cysteine Residue of Epidermal Growth Factor Receptor.
Drug Metab Dispos
; 44(8): 1201-12, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27226351
5.
Decision-making in early clinical drug development.
Pharm Stat
; 15(3): 255-63, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26991401
6.
Osimertinib + Savolitinib to Overcome Acquired MET-Mediated Resistance in Epidermal Growth Factor Receptor-Mutated, MET-Amplified Non-Small Cell Lung Cancer: TATTON.
Cancer Discov
; 13(1): 98-113, 2023 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36264123
7.
Comparing Go/No-Go Decision-Making Properties Between Single Arm Phase II Trial Designs in Oncology.
Ther Innov Regul Sci
; 56(2): 291-300, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34988927
8.
Treatment of patients with the hypereosinophilic syndrome with mepolizumab.
N Engl J Med
; 358(12): 1215-28, 2008 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-18344568
9.
Ceralasertib (AZD6738), an Oral ATR Kinase Inhibitor, in Combination with Carboplatin in Patients with Advanced Solid Tumors: A Phase I Study.
Clin Cancer Res
; 27(19): 5213-5224, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34301752
10.
A Phase Ib Open-Label Multicenter Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancers.
Clin Cancer Res
; 23(18): 5366-5373, 2017 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28615371
11.
Body composition, IGF-I and IGFBP-3 concentrations as outcome measures in severely GH-deficient (GHD) patients after childhood GH treatment: a comparison with adult onset GHD patients.
J Clin Endocrinol Metab
; 87(7): 3368-72, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12107251
12.
Short-term safety and efficacy of human GH replacement therapy in 595 adults with GH deficiency: a comparison of two dosage algorithms.
J Clin Endocrinol Metab
; 87(5): 1974-9, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-11994327
13.
Pergolide versus levodopa monotherapy in early Parkinson's disease patients: The PELMOPET study.
Mov Disord
; 21(3): 343-53, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16211594
14.
Confirmation of severe GH deficiency after final height in patients diagnosed as GH deficient during childhood.
Clin Endocrinol (Oxf)
; 56(4): 503-7, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11966743