Detalhe da pesquisa
1.
Proteogenomic Data Integration Reveals CXCL10 as a Potentially Downstream Causal Mediator for IL-6 Signaling on Atherosclerosis.
Circulation
; 149(9): 669-683, 2024 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38152968
2.
The impact of fatty acids biosynthesis on the risk of cardiovascular diseases in Europeans and East Asians: a Mendelian randomization study.
Hum Mol Genet
; 31(23): 4034-4054, 2022 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35796550
3.
The impact of risk stratification by polygenic risk and age on breast cancer screening in women aged 40-49 years: a modelling study.
Lancet
; 402 Suppl 1: S54, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37997097
4.
APOE ε4 carriage associates with improved myocardial performance from adolescence to older age.
BMC Cardiovasc Disord
; 24(1): 172, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38509472
5.
Utility of polygenic risk scores in UK cancer screening: a modelling analysis.
Lancet Oncol
; 24(6): 658-668, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37178708
6.
Therapeutic Targets for Heart Failure Identified Using Proteomics and Mendelian Randomization.
Circulation
; 145(16): 1205-1217, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35300523
7.
How to assess pharmacogenomic tests for implementation in the NHS in England.
Br J Clin Pharmacol
; 89(9): 2649-2657, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37313748
8.
Comparative Effectiveness and Safety Between Apixaban, Dabigatran, Edoxaban, and Rivaroxaban Among Patients With Atrial Fibrillation : A Multinational Population-Based Cohort Study.
Ann Intern Med
; 175(11): 1515-1524, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36315950
9.
Polygenic risk scores for coronary artery disease and subsequent event risk amongst established cases.
Hum Mol Genet
; 29(8): 1388-1395, 2020 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32219344
10.
Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from over 114,000 UK Biobank participants.
BMC Med
; 20(1): 210, 2022 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35692035
11.
Elevated plasma triglyceride concentration and risk of adverse clinical outcomes in 1.5 million people: a CALIBER linked electronic health record study.
Cardiovasc Diabetol
; 21(1): 102, 2022 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35681241
12.
Plasma proteins, cognitive decline, and 20-year risk of dementia in the Whitehall II and Atherosclerosis Risk in Communities studies.
Alzheimers Dement
; 18(4): 612-624, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34338426
13.
Lipid lowering and Alzheimer disease risk: A mendelian randomization study.
Ann Neurol
; 87(1): 30-39, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31714636
14.
Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis.
J Hepatol
; 73(2): 241-251, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32247823
15.
PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease.
Cochrane Database Syst Rev
; 10: CD011748, 2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33078867
16.
Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration.
J Hepatol
; 71(3): 594-602, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31226389
17.
Variation in Interleukin 6 Receptor Gene Associates With Risk of Crohn's Disease and Ulcerative Colitis.
Gastroenterology
; 155(2): 303-306.e2, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29775600
18.
Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis.
Circulation
; 135(24): 2373-2388, 2017 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28500271
19.
HAPRAP: a haplotype-based iterative method for statistical fine mapping using GWAS summary statistics.
Bioinformatics
; 33(1): 79-86, 2017 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27591082
20.
Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis.
Am J Hum Genet
; 94(2): 198-208, 2014 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24462370