Detalhe da pesquisa
1.
Organic anion-transporting polypeptide 2B1 knockout and humanized mice; insights into the handling of bilirubin and drugs.
Pharmacol Res
; 190: 106724, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36907287
2.
Extrahepatic metabolism of ibrutinib.
Invest New Drugs
; 39(1): 1-14, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32623551
3.
Diagnostic accuracy of breast MRI for patients with suspicious nipple discharge and negative mammography and ultrasound: a prospective study.
Eur Radiol
; 31(10): 7783-7791, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-33846843
4.
Residual cancer burden index and tumor-infiltrating lymphocyte subtypes in triple-negative breast cancer after neoadjuvant chemotherapy.
Breast Cancer Res Treat
; 179(1): 11-23, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31529299
5.
P-glycoprotein Limits Ribociclib Brain Exposure and CYP3A4 Restricts Its Oral Bioavailability.
Mol Pharm
; 16(9): 3842-3852, 2019 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31329454
6.
Brain accumulation of osimertinib and its active metabolite AZ5104 is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein).
Pharmacol Res
; 146: 104297, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31175939
7.
A Targeted LC-MS Strategy for Low-Abundant HLA Class-I-Presented Peptide Detection Identifies Novel Human Papillomavirus T-Cell Epitopes.
Proteomics
; 18(11): e1700390, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29603667
8.
Peptide Processing Is Critical for T-Cell Memory Inflation and May Be Optimized to Improve Immune Protection by CMV-Based Vaccine Vectors.
PLoS Pathog
; 12(12): e1006072, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27977791
9.
Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice.
Hepatology
; 66(5): 1631-1643, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28498614
10.
P-Glycoprotein (MDR1/ABCB1) Restricts Brain Penetration of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib, While Cytochrome P450-3A (CYP3A) Limits Its Oral Bioavailability.
Mol Pharm
; 15(11): 5124-5134, 2018 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30247919
11.
P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) affect brain accumulation and intestinal disposition of encorafenib in mice.
Pharmacol Res
; 129: 414-423, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29155017
12.
Brain Accumulation of Ponatinib and Its Active Metabolite, N-Desmethyl Ponatinib, Is Limited by P-Glycoprotein (P-GP/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2).
Mol Pharm
; 14(10): 3258-3268, 2017 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28880088
13.
Breast cancer resistance protein (BCRP/ABCG2) and P-glycoprotein (P-gp/ABCB1) transport afatinib and restrict its oral availability and brain accumulation.
Pharmacol Res
; 120: 43-50, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28288939
14.
The impact of Organic Anion-Transporting Polypeptides (OATPs) on disposition and toxicity of antitumor drugs: Insights from knockout and humanized mice.
Drug Resist Updat
; 27: 72-88, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27449599
15.
PRognostic factor of Early Death In phase II Trials or the end of 'sufficient life expectancy' as an inclusion criterion? (PREDIT model).
BMC Cancer
; 16(1): 768, 2016 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27716199
16.
[Assessment of the announcement procedure in 29 cancer-accredited hospitals in the Aquitaine region: the EVADA project]. / Évaluation du dispositif dannonce au sein de 29 établissements de santé d'Aquitaine autorisés en cancérologie: le projet EVADA.
Sante Publique
; 27(6): 841-50, 2015.
Artigo
em Francês
| MEDLINE | ID: mdl-26916857
17.
High cumulative risks of cancer in patients with PTEN hamartoma tumour syndrome.
J Med Genet
; 50(4): 255-63, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23335809
18.
Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs.
Biomed Pharmacother
; 175: 116644, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38692057
19.
What next? Preferably development of drugs that are no longer transported by the ABCB1 and ABCG2 efflux transporters.
Pharmacol Res
; 123: 144, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28578203
20.
[Prophylactic mastectomy and occult cancer: a ten-year experience at a cancer center]. / Chirurgie de réduction de risque mammaire et découverte fortuite de cancer : dix ans d'expérience dans un centre de lutte contre le cancer.
Bull Cancer
; 108(11): 999-1009, 2021 Nov.
Artigo
em Francês
| MEDLINE | ID: mdl-34556291