Detalhe da pesquisa
1.
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses.
Immunity
; 56(6): 1341-1358.e11, 2023 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37315536
2.
Identification of invariant chain CD74 as a functional receptor of tissue inhibitor of metalloproteinases-1 (TIMP-1).
J Biol Chem
; 297(3): 101072, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34391782
3.
mTORC1 and mTORC2 Converge on the Arp2/3 Complex to Promote KrasG12D-Induced Acinar-to-Ductal Metaplasia and Early Pancreatic Carcinogenesis.
Gastroenterology
; 160(5): 1755-1770.e17, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33388318
4.
Functional disparities within the TIMP family in cancer: hints from molecular divergence.
Cancer Metastasis Rev
; 38(3): 469-481, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31529339
5.
Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice.
Gastroenterology
; 156(1): 203-217.e20, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30296435
6.
Early pancreatic cancer lesions suppress pain through CXCL12-mediated chemoattraction of Schwann cells.
Proc Natl Acad Sci U S A
; 114(1): E85-E94, 2017 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27986950
7.
Elevated systemic levels of the matrix metalloproteinase inhibitor TIMP-1 correlate with clinical markers of cachexia in patients with chronic pancreatitis and pancreatic cancer.
BMC Cancer
; 18(1): 128, 2018 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29394913
8.
Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver.
Gastroenterology
; 151(5): 1011-1024.e7, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27506299
9.
The induction of human myeloid derived suppressor cells through hepatic stellate cells is dose-dependently inhibited by the tyrosine kinase inhibitors nilotinib, dasatinib and sorafenib, but not sunitinib.
Cancer Immunol Immunother
; 65(3): 273-82, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26786874
10.
Tissue inhibitor of metalloproteinases (TIMP)-1 creates a premetastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil recruitment in mice.
Hepatology
; 61(1): 238-48, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25131778
11.
Tetraspanin CD63 acts as a pro-metastatic factor via ß-catenin stabilization.
Int J Cancer
; 136(10): 2304-15, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25354204
12.
Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15.
Int J Cancer
; 136(4): E14-26, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25099234
13.
TIMP-1 signaling via CD63 triggers granulopoiesis and neutrophilia in mice.
Haematologica
; 100(8): 1005-13, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26001794
14.
Systematic comparison of peptidic proteasome inhibitors highlights the α-ketoamide electrophile as an auspicious reversible lead motif.
Angew Chem Int Ed Engl
; 53(6): 1679-83, 2014 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24403024
15.
Selective inhibition of the immunoproteasome by ligand-induced crosslinking of the active site.
Angew Chem Int Ed Engl
; 53(44): 11969-73, 2014 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25244435
16.
Cut loose TIMP-1: an emerging cytokine in inflammation.
Trends Cell Biol
; 33(5): 413-426, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36163148
17.
TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes.
J Cell Biol
; 222(2)2023 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36629908
18.
Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like neural invasion.
J Clin Invest
; 133(21)2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37607005
19.
Rab31 expression levels modulate tumor-relevant characteristics of breast cancer cells.
Mol Cancer
; 11: 62, 2012 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22920728
20.
Overexpression of the urokinase receptor splice variant uPAR-del4/5 in breast cancer cells affects cell adhesion and invasion in a dose-dependent manner and modulates transcription of tumor-associated genes.
Biol Chem
; 393(12): 1449-55, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23667902