Detalhe da pesquisa
1.
Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy.
Nature
; 615(7953): 668-677, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36890231
2.
Apolipoprotein E4 Reduction with Antisense Oligonucleotides Decreases Neurodegeneration in a Tauopathy Model.
Ann Neurol
; 89(5): 952-966, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33550655
3.
TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis.
Acta Neuropathol
; 140(4): 513-534, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32772264
4.
Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Neuron
; 112(3): 384-403.e8, 2024 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37995685
5.
Parenchymal border macrophages regulate tau pathology and tau-mediated neurodegeneration.
Life Sci Alliance
; 6(11)2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37562846
6.
TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.
Neuron
; 111(2): 202-219.e7, 2023 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36368315
7.
Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia.
Neuron
; 109(10): 1657-1674.e7, 2021 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33831349
8.
Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms.
Neuron
; 109(15): 2413-2426.e7, 2021 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34157306
9.
Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model.
J Exp Med
; 216(11): 2546-2561, 2019 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31601677
10.
TREM2 function impedes tau seeding in neuritic plaques.
Nat Neurosci
; 22(8): 1217-1222, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31235932
11.
Lack of hepatic apoE does not influence early Aß deposition: observations from a new APOE knock-in model.
Mol Neurodegener
; 14(1): 37, 2019 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31623648
12.
The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans.
Science
; 363(6429): 880-884, 2019 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30679382