Detalhe da pesquisa
1.
AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody-Drug Conjugate Production.
Bioconjug Chem
; 2023 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36894324
2.
Chemical Site-Specific Conjugation Platform to Improve the Pharmacokinetics and Therapeutic Index of Antibody-Drug Conjugates.
Mol Pharm
; 18(11): 4058-4066, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34579528
3.
Recent Advances in Drug-Antibody Ratio Determination of Antibody-Drug Conjugates.
Chem Pharm Bull (Tokyo)
; 69(10): 976-983, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34602579
4.
Antibody-Drug Conjugate Payloads; Study of Auristatin Derivatives.
Chem Pharm Bull (Tokyo)
; 68(3): 201-211, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32115527
5.
Comparison of Analytical Methods for Antibody-Drug Conjugates Produced by Chemical Site-Specific Conjugation: First-Generation AJICAP.
Anal Chem
; 91(20): 12724-12732, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31478640
6.
AJICAP: Affinity Peptide Mediated Regiodivergent Functionalization of Native Antibodies.
Angew Chem Int Ed Engl
; 58(17): 5592-5597, 2019 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30854738
7.
Metabolism of an Oxime-Linked Antibody Drug Conjugate, AGS62P1, and Characterization of Its Identified Metabolite.
Mol Pharm
; 15(6): 2384-2390, 2018 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29757653
8.
Investigation of Hydrophilic Auristatin Derivatives for Use in Antibody Drug Conjugates.
Bioconjug Chem
; 28(2): 371-381, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28060485
9.
Synthesis and Evaluation of Dolastatin 10 Analogues Containing Heteroatoms on the Amino Acid Side Chains.
J Nat Prod
; 80(9): 2484-2491, 2017 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28885014
10.
AJICAP-M: Traceless Affinity Peptide Mediated Conjugation Technology for Site-Selective Antibody-Drug Conjugate Synthesis.
Org Lett
; 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38639400
11.
Biological Evaluation of Maytansinoid-Based Site-Specific Antibody-Drug Conjugate Produced by Fully Chemical Conjugation Approach: AJICAP®.
Front Biosci (Landmark Ed)
; 27(8): 234, 2022 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36042175
12.
Oxidation of α-oxo-oximes to nitrile oxides with hypervalent iodine reagents.
J Org Chem
; 76(2): 728-31, 2011 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21175144
13.
An overview of process development for antibody-drug conjugates produced by chemical conjugation technology.
Expert Opin Biol Ther
; 21(7): 963-975, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33141625
14.
In-situ Reverse Phased HPLC Analysis of Intact Antibody-Drug Conjugates.
Anal Sci
; 37(8): 1171-1176, 2021 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33518587
15.
Physical characteristics comparison between maytansinoid-based and auristatin-based antibody-drug conjugates.
Explor Target Antitumor Ther
; 2(6): 576-585, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-36046112
16.
Chromatographic analysis of site-specific antibody-drug conjugates produced by AJICAP first-generation technology using a recombinant FcγIIIa receptor-ligand affinity column.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1177: 122753, 2021 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34098178
17.
Application of Native Ion Exchange Mass Spectrometry to Intact and Subunit Analysis of Site-Specific Antibody-Drug Conjugates Produced by AJICAP First Generation Technology.
J Am Soc Mass Spectrom
; 2020 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32608232
18.
Proof of site-specificity of antibody-drug conjugates produced by chemical conjugation technology: AJICAP first generation.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1140: 121981, 2020 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32036254
19.
Analytical Comparison of Antibody-drug Conjugates Based on Good Manufacturing Practice Strategies.
Anal Sci
; 36(7): 871-875, 2020 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32336726
20.
Synthesis and Biological Evaluation of Antibody Drug Conjugates Based on an Antibody Expression System: Conamax.
ACS Omega
; 5(13): 7193-7200, 2020 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32280859