Detalhe da pesquisa
1.
Investigation of the P1' and P2' sites of IQF substrates and their selectivity toward 20S proteasome subunits.
Biol Chem
; 404(2-3): 221-227, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36376064
2.
SARS-CoV-2 Mpro inhibitors and activity-based probes for patient-sample imaging.
Nat Chem Biol
; 17(2): 222-228, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33093684
3.
Multiplexed Probing of Proteolytic Enzymes Using Mass Cytometry-Compatible Activity-Based Probes.
J Am Chem Soc
; 142(39): 16704-16715, 2020 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32870676
4.
Small Molecule Active Site Directed Tools for Studying Human Caspases.
Chem Rev
; 115(22): 12546-629, 2015 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26551511
5.
Structure and substrate fingerprint of aminopeptidase P from Plasmodium falciparum.
Biochem J
; 473(19): 3189-204, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27462122
6.
Human 20S proteasome activity towards fluorogenic peptides of various chain lengths.
Biol Chem
; 397(9): 921-6, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27176742
7.
SARS hCoV papain-like protease is a unique Lys48 linkage-specific di-distributive deubiquitinating enzyme.
Biochem J
; 468(2): 215-26, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25764917
8.
Recent advances and concepts in substrate specificity determination of proteases using tailored libraries of fluorogenic substrates with unnatural amino acids.
Biol Chem
; 396(4): 329-37, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25719315
9.
Differential specificity of SARS-CoV-2 main protease variants on peptide versus protein-based substrates.
FEBS J
; 291(1): 61-69, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37843490
10.
Chemical tools to define and manipulate interferon-inducible Ubl protease USP18.
bioRxiv
; 2024 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38645224
11.
Design and Synthesis of Ubiquitin-Based Chemical Tools with Unnatural Amino Acids for Selective Detection of Deubiquitinases.
Methods Mol Biol
; 2591: 59-78, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36350543
12.
Mapping the substrate-binding subsite specificity of a Porphyromonas gingivalis Tpr peptidase.
Acta Biochim Pol
; 70(4): 963-968, 2023 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38063852
13.
Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase.
Sci Rep
; 13(1): 9161, 2023 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37280236
14.
SARS-CoV-2 Mpro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals.
ACS Cent Sci
; 9(4): 696-708, 2023 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37122453
15.
Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections.
Commun Biol
; 6(1): 1058, 2023 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37853179
16.
Evaluation of the anti-SARS-CoV-2 properties of essential oils and aromatic extracts.
Sci Rep
; 12(1): 14230, 2022 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35987981
17.
A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease.
Cell Rep
; 36(13): 109754, 2021 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34547223
18.
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
J Med Chem
; 64(10): 6706-6719, 2021 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34006103
19.
Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.
Cell Rep
; 37(4): 109892, 2021 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34672947
20.
Profiling of flaviviral NS2B-NS3 protease specificity provides a structural basis for the development of selective chemical tools that differentiate Dengue from Zika and West Nile viruses.
Antiviral Res
; 175: 104731, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32014497