Detalhe da pesquisa
1.
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.
Hum Mol Genet
; 23(16): 4420-32, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24688116
2.
Genetic and epigenetic regulation of gene expression in fetal and adult human livers.
BMC Genomics
; 15: 860, 2014 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25282492
3.
Transcriptome analysis reveals involvement of thiopurine S-methyltransferase in oxidation-reduction processes.
Eur J Pharm Sci
; 192: 106616, 2024 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37865284
4.
Epigenetic quantification of immunosenescent CD8+ TEMRA cells in human blood.
Aging Cell
; 21(5): e13607, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35397197
5.
Unique spectrum of SPAST variants in Estonian HSP patients: presence of benign missense changes but lack of exonic rearrangements.
BMC Neurol
; 10: 17, 2010 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20214791
6.
Monocytes present age-related changes in phospholipid concentration and decreased energy metabolism.
Aging Cell
; 19(4): e13127, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32107839
7.
Determination of thiopurine S-methyltransferase (TPMT) activity by comparing various normalization factors: reference values for Estonian population using HPLC-UV assay.
J Chromatogr B Analyt Technol Biomed Life Sci
; 834(1-2): 77-83, 2006 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-16517227
8.
Novel human pathological mutations. Gene symbol: SPAST. Disease: Hereditary spastic paraplegia.
Hum Genet
; 127(1): 112, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20108387
9.
From pharmacogenetics to pharmacometabolomics: SAM modulates TPMT activity.
Pharmacogenomics
; 15(11): 1437-49, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25303295
10.
Post-translational stabilization of thiopurine S-methyltransferase by S-adenosyl-L-methionine reveals regulation of TPMT*1 and *3C allozymes.
Biochem Pharmacol
; 83(7): 969-76, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22274639
11.
Selection for genetic variation inducing pro-inflammatory responses under adverse environmental conditions in a Ghanaian population.
PLoS One
; 4(11): e7795, 2009 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-19907653
12.
Thiopurine S-methyltransferase (TPMT) pharmacogenetics: three new mutations and haplotype analysis in the Estonian population.
Clin Chem Lab Med
; 46(7): 974-9, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18605963