Detalhe da pesquisa
1.
A General Dual-Metal Nanocrystal Dissociation Strategy to Generate Robust High-Temperature-Stable Alumina-Supported Single-Atom Catalysts.
J Am Chem Soc
; 145(29): 15869-15878, 2023 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37449950
2.
Design and synthesis of aminopyridine containing biaryls reducing c-MYC protein levels in cells.
Bioorg Med Chem Lett
; 92: 129385, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37339719
3.
Electronically Engineering Water Resistance in Methane Combustion with an Atomically Dispersed Tungsten on PdO Catalyst.
Angew Chem Int Ed Engl
; 61(27): e202201655, 2022 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35429218
4.
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations.
Nature
; 492(7427): 108-12, 2012 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23051747
5.
Diels-Alder reactions of 12-hydroxy-9(10®20)-5aH-abeo-abieta-1(10),8(9),12(13)-triene-11,14-dione.
Molecules
; 18(6): 6969-89, 2013 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23771059
6.
Yangqing Chenfei formula alleviates silica-induced pulmonary inflammation in rats by inhibiting macrophage M1 polarization.
Chin Med
; 18(1): 79, 2023 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37381044
7.
[Digoxin alleviates pulmonary fibrosis by regulating phosphatidylinositol-3-kinase/Akt signaling through inhibiting the activation of fibroblast: an in vivo and in vitro experiment].
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
; 34(11): 1161-1166, 2022 Nov.
Artigo
em Zh
| MEDLINE | ID: mdl-36567559
8.
Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening.
J Med Chem
; 65(21): 14391-14408, 2022 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36302181
9.
Cell-Based Drug Discovery: Identification and Optimization of Small Molecules that Reduce c-MYC Protein Levels in Cells.
J Med Chem
; 64(21): 16056-16087, 2021 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34669409
10.
Design, synthesis, and evaluation of proline and pyrrolidine based melanocortin receptor agonists. A conformationally restricted dipeptide mimic approach.
J Med Chem
; 49(15): 4745-61, 2006 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-16854081
11.
A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC.
Cancer Cell
; 28(1): 57-69, 2015 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26175415
12.
Synthesis and pharmacological evaluation of 3-(3,4-dichlorophenyl)-1-indanamine derivatives as nonselective ligands for biogenic amine transporters.
J Med Chem
; 47(10): 2624-34, 2004 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15115403
13.
Use of Conjugated Dienones in Cyclialkylations: The Total Syntheses of (+/-)-Barbatusol, (+/-)-Pisiferin, (+/-)-Deoxofaveline, (+/-)-Xochitlolone, and (+/-)-Faveline.
J Org Chem
; 61(23): 8169-8185, 1996 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-11667805
14.
Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2.
ACS Med Chem Lett
; 3(12): 1091-6, 2012 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900432
15.
Discovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agents.
J Med Chem
; 51(19): 6055-66, 2008 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18771254
16.
Synthesis of Tic-D-Phe Psi[CH2-CH2] isostere and its use in the development of melanocortin receptor agonists.
Bioorg Med Chem Lett
; 16(6): 1721-5, 2006 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16376076
17.
Design and synthesis of potent and selective 1,3,4-trisubstituted-2-oxopiperazine based melanocortin-4 receptor agonists.
Bioorg Med Chem Lett
; 16(17): 4668-73, 2006 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16766182
18.
Design, synthesis, and evaluation of proline based melanocortin receptor ligands.
Bioorg Med Chem Lett
; 15(11): 2819-23, 2005 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-15911261
19.
Probes for narcotic receptor-mediated phenomena. 33. Construction of a strained trans-5,6-ring system by displacement of a nitro-activated aromatic fluorine. synthesis of the penultimate oxide-bridged phenylmorphans.
J Org Chem
; 69(16): 5322-7, 2004 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15287777
20.
CRHR1 Receptor binding and lipophilicity of pyrrolopyrimidines, potential nonpeptide corticotropin-releasing hormone type 1 receptor antagonists.
Bioorg Med Chem
; 10(1): 175-83, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11738619