Detalhe da pesquisa
1.
Lack of Evidence that CYTH2/ARNO Functions as a Direct Intracellular EGFR Activator.
Cell
; 165(5): 1031-1034, 2016 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27203102
2.
Dissection of the general two-step di-C-glycosylation pathway for the biosynthesis of (iso)schaftosides in higher plants.
Proc Natl Acad Sci U S A
; 117(48): 30816-30823, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33199630
3.
Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors.
Nature
; 534(7605): 129-32, 2016 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27251290
4.
Structural Basis of Specificity for Carboxyl-Terminated Acyl Donors in a Bacterial Acyltransferase.
J Am Chem Soc
; 142(37): 16031-16038, 2020 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32803979
5.
Functional Characterization and Structural Basis of an Efficient Di-C-glycosyltransferase from Glycyrrhiza glabra.
J Am Chem Soc
; 142(7): 3506-3512, 2020 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31986016
6.
Acetylation of 53BP1 dictates the DNA double strand break repair pathway.
Nucleic Acids Res
; 46(2): 689-703, 2018 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29190394
7.
Molecular and Structural Characterization of a Promiscuous C-Glycosyltransferase from Trollius chinensis.
Angew Chem Int Ed Engl
; 58(33): 11513-11520, 2019 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31163097
8.
Crystal structures of pan-IDH inhibitor AG-881 in complex with mutant human IDH1 and IDH2.
Biochem Biophys Res Commun
; 503(4): 2912-2917, 2018 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30131249
9.
Crystal structure of EGFR T790M/C797S/V948R in complex with EAI045.
Biochem Biophys Res Commun
; 502(3): 332-337, 2018 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29802850
10.
Structural pharmacological studies on EGFR T790M/C797S.
Biochem Biophys Res Commun
; 488(2): 266-272, 2017 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28456628
11.
Cartilage oligomeric matrix protein is a natural inhibitor of thrombin.
Blood
; 126(7): 905-14, 2015 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26045608
12.
Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors.
Proc Natl Acad Sci U S A
; 111(45): E4869-77, 2014 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25349422
13.
Structural and biochemical studies of the PDGFRA kinase domain.
Biochem Biophys Res Commun
; 477(4): 667-672, 2016 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27349873
14.
Mechanism for activation of mutated epidermal growth factor receptors in lung cancer.
Proc Natl Acad Sci U S A
; 110(38): E3595-604, 2013 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24019492
15.
Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity.
Cancer Cell
; 11(3): 217-27, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17349580
16.
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M.
Nature
; 462(7276): 1070-4, 2009 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20033049
17.
Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.
Proc Natl Acad Sci U S A
; 109(36): 14476-81, 2012 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22908275
18.
Structure, catalysis, chitin transport, and selective inhibition of chitin synthase.
Nat Commun
; 14(1): 4776, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37553334
19.
Structure of a fungal 1,3-ß-glucan synthase.
Sci Adv
; 9(37): eadh7820, 2023 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37703377
20.
Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase.
Science
; 379(6636): 996-1003, 2023 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36893255