Employment and child support outcomes among noncustodial fathers: An evaluation of the Fathers Advancing Community Together program.

Prior research underscores the importance of fathers' involvement in their children's lives. However, there is mixed evidence about the degree to which fatherhood programs improve economic stability and child support outcomes among noncustodial fathers. We attempted to address some of these gaps in the literature by evaluating the Fathers Advancing Community Together (FACT) program. FACT was implemented by Rubicon Programs, a community-based nonprofit organization in the Bay Area, California known for providing services to help move people out of poverty. The program provided parents economic stability, responsible parenting, and healthy relationship workshops, as well as support services and intensive case management. We relied on data from the Department of Child Support Services to assess whether FACT increased the likelihood of employment, child support modifications, and child support payments among noncustodial fathers during a 6-month post-enrollment period. Using 3:1 coarsened exact matching procedures, the total sample resulted in 744 fathers (186 in the intervention group and 558 in the comparison group). Results from logistic regression models indicate that FACT participants were more likely to be employed and more likely to receive a child support modification during the post-enrollment period than their comparison counterparts, though we found no significant relationship between FACT participation and whether fathers made a child support payment.

Investigaciones previas subrayan la importancia de la participación de los padres en las vidas de sus hijos. Sin embargo, hay datos contradictorios acerca del grado en el cual los programas sobre la paternidad mejoran los resultados en la estabilidad económica y la manutención infantil entre los padres que no tienen la custodia de sus hijos. Intentamos abordar algunos de estos vacíos en las publicaciones evaluando el programa "Padres que fomentan la comunidad juntos" (Fathers Advancing Community Together, FACT). El programa FACT fue implementado por Rubicon Programs, una organización comunitaria sin fines de lucro en el Área de la Bahía de California, conocida por prestar servicios para ayudar a las personas a salir de la pobreza. El programa ofreció talleres de estabilidad económica para los padres, crianza responsable y relaciones sanas, así como servicios de apoyo y gestión intensiva de casos. Utilizamos datos del Departamento de Servicios de Manutención Infantil (Department of Child Support Services) para evaluar si el FACT aumentó la probabilidad de empleo, las modificaciones en la manutención infantil y los pagos de la manutención infantil entre padres sin la custodia de sus hijos durante un periodo de seis meses posterior a la inscripción. Utilizando métodos de emparejamiento exacto 3:1, la muestra total dio como resultado 744 padres (186 en el grupo de intervención y 558 en el grupo de comparación). Los resultados de los modelos de regresión logística indican que los participantes del FACT tuvieron más probabilidades de ser empleados y de recibir una modificación en la manutención infantil durante el periodo posterior a la inscripción que sus homólogos del grupo de de comparación, aunque no encontramos una relación significativa entre la participación en el FACT y si los padres hicieron un pago de manutención infantil.

Subjective modeling choices and the robustness of impact evaluations in conservation science.

Arbitrary modeling choices are inevitable in scientific studies. Yet, few empirical studies in conservation science report the effects these arbitrary choices have on estimated results. I explored the effects of subjective modeling choices in the context of counterfactual impact evaluations. Over 5000 candidate models based on reasonable changes in the choice of statistical matching algorithms (e.g., genetic and nearest distance mahalanobis matching), the parametrization of these algorithms (e.g., number of matches), and the inclusion of specific covariates (e.g., distance to nearest city, slope, or rainfall) were valid for studying the effect of Virunga National Park in Democratic Republic of the Congo on changes in tree cover loss and carbon storage over time. I randomly picked 2000 of the 5000 candidate models to determine how much and which subjective modeling choices affected the results the most. All valid models indicated that tree cover loss decreased and carbon storage increased in Virunga National Park from 2000 to 2019. Nonetheless, the order of magnitude of the estimates varied by a factor of 3 (from -4.78 to -13.12 percentage points decrease in tree cover loss and from 20 to 46 t Ce/ha for carbon storage). My results highlight that modeling choices, notably the choice of the matching algorithm, can have significant effects on point estimates and suggest that more structured robustness checks are a key step toward more credible findings in conservation science.

Selecciones Subjetivas de Modelos y la Contundencia de las Evaluaciones de Impacto en las Ciencias de la Conservación Resumen Las selecciones arbitrarias de modelos son inevitables en los estudios científicos. Sin embargo, pocos estudios empíricos en las ciencias de la conservación reportan los efectos de estas selecciones arbitrarias sobre los resultados estimados. Exploré los efectos de las selecciones subjetivas de modelos en el contexto de las evaluaciones de impacto contrafactuales. Más de 5000 modelos candidatos basados en cambios razonables en la elección de los algoritmos de emparejamiento estadístico (p. ej.: emparejamiento genético y de distancia más cercana mahalanobis), la parametrización de estos algoritmos (p. ej.: número de parejas) y la inclusión de covariados específicos (p. ej.: distancia a la ciudad más cercana, inclinación, precipitación) fueron válidos para estudiar el efecto del Parque Nacional Virunga en la República Democrática del Congo sobre la pérdida de cobertura arbórea y el almacenamiento de carbono a través del tiempo. Escogí al azar 2000 de los 5000 modelos candidatos para determinar cuántos y cuáles selecciones subjetivas de los modelos afectaron más al resultado. Todos los modelos válidos indicaron que la pérdida de la cobertura arbórea disminuyó y el almacenamiento de carbono incrementó en el Parque Nacional Virunga desde entre el año 2000 y el 2019. No obstante, el orden de magnitud de las estimaciones varió con un factor de 3 (una disminución de -4.78 hasta -13.12 puntos porcentuales en la pérdida de la cobertura arbórea y de 20 hasta 46 t Ce/ha para el almacenamiento de carbono). Mis resultados resaltan que la selección de los modelos, notablemente la elección del algoritmo de emparejamiento, puede tener efectos significativos sobre las estimaciones de puntos y sugieren que las revisiones más estructuradas de la contundencia son un paso importante hacia descubrimientos más creíbles en las ciencias de la conservación.

Effects of spatial autocorrelation and sampling design on estimates of protected area effectiveness.

Estimating the effectiveness of protected areas (PAs) in reducing deforestation is useful to support decisions on whether to invest in better management of areas already protected or to create new ones. Statistical matching is commonly used to assess this effectiveness, but spatial autocorrelation and regional differences in protection effectiveness are frequently overlooked. Using Colombia as a case study, we employed statistical matching to account for confounding factors in park location and accounted for for spatial autocorrelation to determine statistical significance. We compared the performance of different matching procedures-ways of generating matching pairs at different scales-in estimating PA effectiveness. Differences in matching procedures affected covariate similarity between matched pairs (balance) and estimates of PA effectiveness in reducing deforestation. Independent matching yielded the greatest balance. On average 95% of variables in each region were balanced with independent matching, whereas 33% of variables were balanced when using the method that performed worst. The best estimates suggested that average deforestation inside protected areas in Colombia was 40% lower than in matched sites. Protection significantly reduced deforestation, but PA effectiveness differed among regions. Protected areas in Caribe were the most effective, whereas those in Orinoco and Pacific were least effective. Our results demonstrate that accounting for spatial autocorrelation and using independent matching for each subset of data is needed to infer the effectiveness of protection in reducing deforestation. Not accounting for spatial autocorrelation can distort the assessment of protection effectiveness, increasing type I and II errors and inflating effect size. Our method allowed improved estimates of protection effectiveness across scales and under different conditions and can be applied to other regions to effectively assess PA performance.

Efectos de la Autocorrelación Espacial y el Diseño del Muestreo sobre las Estimaciones de la Efectividad de Áreas Protegidas Resumen La estimación de la efectividad de las áreas protegidas (AP) para reducir la deforestación es útil al momento de respaldar las decisiones que eligen entre invertir en un mejor manejo de las áreas ya protegidas o crear áreas nuevas. El emparejamiento estadístico es la herramienta utilizada con mayor frecuencia para evaluar esta efectividad, pero casi siempre se ignora la autocorrelación especial y las diferencias regionales en la efectividad de la protección. Con Colombia como caso de estudio, empleamos un emparejamiento estadístico para controlar el efecto de factores relacionados con la ubicación la ubicación de los parques y he incluimos el efecto de la autocorrelación especial para determinar la significancia estadística. Comparamos el desempeño de los diferentes procedimientos de emparejamiento - las maneras de generar pares a diferentes escalas - en la estimación de la efectividad de las AP. Las diferencias en los procedimientos de emparejamiento afectaron la similitud de la covarianza entre los pares emparejados (balance) y la estimación de la efectividad de las AP en la reducción de la deforestación. El emparejamiento independiente produjo el mayor balance. En promedio, el 95% de las variables en cada región estuvo balanceado con el emparejamiento independiente, mientras que el 24% de las variables estuvo balanceado cuando se usó el método con el peor desempeño. Las mejores estimaciones sugieren que la deforestación media dentro de las áreas protegidas en Colombia era 40% menor que en los sitios emparejados emparejados. La protección redujo significativamente la deforestación, aunque la efectividad de las AP difirió entre las regiones. Las AP en la región Caribe fueron las más efectivas, mientras que aquellas en la Orinoquía y el Pacífico fueron las menos efectivas. Nuestros resultados demuestran que se necesita considerar la autocorrelación espacial y usar el emparejamiento independiente para cada subconjunto de datos para inferir la efectividad de la protección en la reducción de la deforestación. Si no se considera la autocorrelación espacial, se pueden distorsionar los estimativos de la efectividad de la protección, incrementando los errores de tipo I y II e inflando el tamaño del efecto. Nuestro método permitió obtener mejores estimaciones de la efectividad de la protección en todas las escalas y bajo diferentes condiciones y puede aplicarse a otras regiones para evaluar de manera efectiva el desempeño de las AP.

Mechanisms and impacts of an incentive-based conservation program with evidence from a randomized control trial.

Conservation science needs more high-quality impact evaluations, especially ones that explore mechanisms of success or failure. Randomized control trials (RCTs) provide particularly robust evidence of the effectiveness of interventions (although they have been criticized as reductionist and unable to provide insights into mechanisms), but there have been few such experiments investigating conservation at the landscape scale. We explored the impact of Watershared, an incentive-based conservation program in the Bolivian Andes, with one of the few RCTs of landscape-scale conservation in existence. There is strong interest in such incentive-based conservation approaches as some argue they can avoid negative social impacts sometimes associated with protected areas. We focused on social and environmental outcomes based on responses from a household survey in 129 communities randomly allocated to control or treatment (conducted both at the baseline in 2010 and repeated in 2015-2016). We controlled for incomplete program uptake by combining standard RCT analysis with matching methods and investigated mechanisms by exploring intermediate and ultimate outcomes according to the underlying theory of change. Previous analyses, focused on single biophysical outcomes, showed that over its first 5 years Watershared did not slow deforestation or improve water quality at the landscape scale. We found that Watershared influenced some outcomes measured using the survey, but the effects were complex, and some were unexpected. We thus demonstrated how RCTs can provide insights into the pathways of impact, as well as whether an intervention has impact. This paper, one of the first registered reports in conservation science, demonstrates how preregistration can help make complex research designs more transparent, avoid cherry picking, and reduce publication bias.

Mecanismos e Impactos de un Programa de Conservación Basada en Incentivos con Evidencias de un Ensayo Aleatorio de Control Resumen Las ciencias de la conservación necesitan evaluaciones de impacto de mayor calidad, especialmente aquellas que exploran los mecanismos del éxito o del fracaso. Los ensayos aleatorios de control (RCTs) proporcionan evidencias particularmente sólidas de la efectividad de las intervenciones (aunque han recibido críticas por considerarlas reduccionistas e incapaces de proporcionar conocimiento sobre los mecanismos) pero ha habido pocos experimentos de ese tipo que investiguen los efectos de la conservación a escala del paisaje. Exploramos el impacto de Watershared, un programa de conservación basada en incentivos en marcha en los Andes bolivianos, con uno de los pocos RCTs existentes de conservación a escala de paisaje. Existe un gran interés por dichas estrategias de conservación basada en incentivos pues hay quienes argumentan que pueden evitar los impactos sociales negativos que a veces se asocian con las áreas protegidas. Nos enfocamos en los resultados sociales y ambientales con base en las respuestas de una encuesta a hogares en 129 comunidades asignadas al azar para controlar o tratar (ambas encuestas realizadas en la línea base en 2010 y repetidas en 2015/16). Impusimos un control para la aceptación incompleta del programa al combinar el análisis estandarizado de RCTs con métodos de emparejamiento e investigamos los mecanismos mediante la exploración de resultados intermedios y finales de acuerdo con la teoría subyacente del cambio. Los análisis previos, enfocados en resultados biofísicos únicos, mostraron que durante los primeros cinco años del programa Watershared, la deforestación no experimentó una desaceleración y tampoco hubo mejoras en la calidad del agua a escala de paisaje. Descubrimos que Watershared influyó sobre algunos resultados medidos con la encuesta, pero sus efectos fueron complejos y algunos fueron inesperados. De este modo demostramos como los RCTs pueden proporcionar conocimiento sobre las vías de impacto, así como también si una intervención genera un impacto. Este artículo, uno de los primeros reportes registrados en las ciencias de la conservación, demuestra cómo el prerregistro puede ayudar a hacer más transparentes los diseños complejos de investigación, evitar la selección subjetiva de datos y reducir el sesgo de publicación.

Effectiveness of Africa's tropical protected areas for maintaining forest cover.

The effectiveness of parks for forest conservation is widely debated in Africa, where increasing human pressure, insufficient funding, and lack of management capacity frequently place significant demands on forests. Tropical forests house a substantial portion of the world's remaining biodiversity and are heavily affected by anthropogenic activity. We analyzed park effectiveness at the individual (224 parks) and national (23 countries) level across Africa by comparing the extent of forest loss (as a proxy for deforestation) inside parks to matched unprotected control sites. Although significant geographical variation existed among parks, the majority of African parks had significantly less forest loss within their boundaries (e.g., Mahale Park had 34 times less forest loss within its boundary) than control sites. Accessibility was a significant driver of forest loss. Relatively inaccessible areas had a higher probability (odds ratio >1, p < 0.001) of forest loss but only in ineffective parks, and relatively accessible areas had a higher probability of forest loss but only in effective parks. Smaller parks less effectively prevented forest loss inside park boundaries than larger parks (T = -2.32, p < 0.05), and older parks less effectively prevented forest loss inside park boundaries than younger parks (F2,154 = -4.11, p < 0.001). Our analyses, the first individual and national assessment of park effectiveness across Africa, demonstrated the complexity of factors (such as geographical variation, accessibility, and park size and age) influencing the ability of a park to curb forest loss within its boundaries.

Effects of national forest-management regimes on unprotected forests of the Himalaya.

Globally, deforestation continues, and although protected areas effectively protect forests, the majority of forests are not in protected areas. Thus, how effective are different management regimes to avoid deforestation in non-protected forests? We sought to assess the effectiveness of different national forest-management regimes to safeguard forests outside protected areas. We compared 2000-2014 deforestation rates across the temperate forests of 5 countries in the Himalaya (Bhutan, Nepal, China, India, and Myanmar) of which 13% are protected. We reviewed the literature to characterize forest management regimes in each country and conducted a quasi-experimental analysis to measure differences in deforestation of unprotected forests among countries and states in India. Countries varied in both overarching forest-management goals and specific tenure arrangements and policies for unprotected forests, from policies emphasizing economic development to those focused on forest conservation. Deforestation rates differed up to 1.4% between countries, even after accounting for local determinants of deforestation, such as human population density, market access, and topography. The highest deforestation rates were associated with forest policies aimed at maximizing profits and unstable tenure regimes. Deforestation in national forest-management regimes that emphasized conservation and community management were relatively low. In India results were consistent with the national-level results. We interpreted our results in the context of the broader literature on decentralized, community-based natural resource management, and our findings emphasize that the type and quality of community-based forestry programs and the degree to which they are oriented toward sustainable use rather than economic development are important for forest protection. Our cross-national results are consistent with results from site- and regional-scale studies that show forest-management regimes that ensure stable land tenure and integrate local-livelihood benefits with forest conservation result in the best forest outcomes.

Phenological mismatch and the effectiveness of assisted gene flow.

The persistence of narrowly adapted species under climate change will depend on their ability to migrate apace with their historical climatic envelope or to adapt in place to maintain fitness. This second path to persistence can only occur if there is sufficient genetic variance for response to new selection regimes. Inadequate levels of genetic variation can be remedied through assisted gene flow (AGF), that is the intentional introduction of individuals genetically adapted to localities with historic climates similar to the current or future climate experienced by the resident population. However, the timing of reproduction is frequently adapted to local conditions. Phenological mismatch between residents and migrants can reduce resident × migrant mating frequencies, slowing the introgression of migrant alleles into the resident genetic background and impeding evolutionary rescue efforts. Focusing on plants, we devised a method to estimate the frequency of resident × migrant matings based on flowering schedules and applied it in an experiment that mimicked the first generation of an AGF program with Chamaecrista fasciculata, a prairie annual, under current and expected future temperature regimes. Phenological mismatch reduced the potential for resident × migrant matings by 40-90%, regardless of thermal treatment. The most successful migrant sires were the most resident like in their flowering time, further biasing the genetic admixture between resident and migrant populations. Other loci contributing to local adaptation-heat-tolerance genes, for instance-may be in linkage disequilibrium with phenology when residents and migrants are combined into a single mating pool. Thus, introgression of potentially adaptive migrant alleles into the resident genetic background is slowed when selection acts against migrant phenology. Successful AGF programs may require sustained high immigration rates or preliminary breeding programs when phenologically matched migrant source populations are unavailable.

Mismatch repair system in colorectal cancer. Frequency, cancer phenotype, and follow-up.

INTRODUCTION AND AIMS: A frequent task in the study of colorectal carcinomas (CRC) is to identify tumors harboring deficient DNA mismatch repair systems (dMMR), which are associated with microsatellite instability. Given that there is scant information on those tumors in Mexican patients, our aim was to describe their frequency, clinical and pathologic characteristics, and results, which are necessary for future trials. MATERIALS AND METHODS: A consecutive series of CRC patients, treated and followed at a tertiary care center was performed. The clinical and pathologic variables and the risk of hereditary or familial cancer syndrome were retrieved. The original slides and hMLH1, hPMS2, hMSH2, hMSH6 immunohistochemistry were evaluated. Tumors with an absence of at least one protein were considered dMMR. Differences were contrasted, utilizing non-parametric tests. RESULTS: One hundred and forty-four patients were included, with a median age of 65 years. A total of 134/93% patients presented with sporadic CRC, 8/5.6% had a family history of CRC, and 2/1.4% met the diagnostic criteria for hereditary non-polyposis colon cancer, according to the Amsterdam and Bethesda criteria. dMMR tumors were found in 39 patients, distributed among the three groups. They were locally advanced (p<0.001), right-sided, had the mucinous phenotype, and harbored a Crohn's-like lymphoid reaction (all three features, p<0.04). Adjuvant or palliative chemotherapy was administered to 57 (39.6%), concomitant chemoradiotherapy to 24 (16.7%), but 63 (43.8%) patients received no additional treatment to surgery. Five-year follow-up was completed in 131 of the patients and the outcomes alive-with-disease or died-of-disease were more frequently observed in the proficient (pMMR) lesions. CONCLUSIONS: In the present pre-FOLFOX case series, outcomes were better in dMMR CRC than in proficient lesions.

No effect of desmopressin administration before kidney biopsy on the risk of major post-biopsy bleeding.

BACKGROUND/AIMS: The most important complication of kidney biopsy is bleeding, and it is unclear whether desmopressin is effective in preventing it. Thus, the study was conducted to compare post-biopsy bleeding with or without desmopressin prescription prior to percutaneous kidney biopsy. METHODS: In this single-centered, retrospective, and observational study, 3,018 adult patients who underwent kidney biopsy between January 1, 2003 and March 31, 2019 at our institute were recruited. Of these, 776 patients received desmopressin. To compare the differences in major bleeding events between patients administered and not administered with desmopressin, propensity score matching was performed. RESULTS: Before propensity score (PS) matching, it was observed that patients in the desmopressin group were significantly older (p<0.001) and had a higher blood pressure (p<0.001), higher serum creatinine (p<0.001), lower hemoglobin levels (p<0.001), and lower platelet counts (p=0.001) than those in the no-desmopressin group. Furthermore, the incidence of renal artery embolization was not significantly different between the two groups (p=0.077); however, blood transfusions occurred significantly more frequently in the desmopressin group (p<0.001). A comparison of the two groups after PS matching did not reveal any differences in the incidence of renal artery embolization (p=0.341), blood transfusion (p=0.579), and total major bleeding events (p=0.442). Furthermore, there was no difference in the incidence of perinephric hematoma on computed tomography or ultrasound (p=0.120). CONCLUSIONS: We do not recommend desmopressin administration before kidney biopsy.

Endoscopic versus open surgery in patients with malignant sinonasal tumours and brain invasion. A case series study.

OBJECTIVES: To determine the safety, effectiveness and perioperative costs of endonasal endoscopic approach in brain invasive malignant sinonsal tumours patients. MATERIALS AND METHODS: This was a case series bidirectional study; that included 30 brain invasive malignant sinonsal tumours patients treated by endonasal endoscopic approach (2015-2017) and 53 by open surgery (2010-2015). Propensity score matching was used to compensate the prognostic factors; in a sample of 50 patients (25 per group). Primary response variables was local control and 3-years overall survival. Perioperative cost variables were analyzed. RESULTS: A number of 50 patients were included after matching (25 in each therapeutic group). The age average was 55 years and male proportion was 62%. Squamous cell carcinoma and grade II lesions were the most represented in the sample. Endonasal endoscopic approach reduced surgical time in 1 h 20 min, transfusion needs in 5.5 fold and hospitalization in 19 days; in comparison with open technique. Oncologic control based on surgical free margins, local control, overall survival and progression free survival after three years was higher when the resection was performed endoscopically. Functional status was enhanced and complications diminished by using endoscopic approach. Saving was estimated in $7 355.18 per patient. CONCLUSIONS: Endonasal endoscopic approach represents a safe, effective and economic procedure in selected patients with malignant sinonasal tumors and brain invasion.

Endoscopic versus open surgery in patients with malignant sinonasal tumors and brain invasion. A case series study. / Cirugía endoscópica vs. cirugía abierta en pacientes con neoplasias nasosinusales malignas con invasión cerebral. Estudio de serie de casos.

OBJECTIVES: To determine the safety, effectiveness and perioperative costs of endonasal endoscopic approach in brain invasive malignant sinonsal tumors patients. MATERIALS AND METHODS: This was a case series bidirectional study; that included 30 brain invasive malignant sinonsal tumors patients treated by endonasal endoscopic approach (2015-2017) and 53 by open surgery (2010-2015). Propensity score matching was used to compensate the prognostic factors; in a sample of 50 patients (25 per group). Primary response variables was local control and 3-years overall survival. Perioperative cost variables were analyzed. RESULTS: A number of 50 patients were included after matching (25 in each therapeutic group). The age average was 55 years and male proportion was 62%. Squamous cell carcinoma and grade II lesions were the most represented in the sample. Endonasal endoscopic approach reduced surgical time in 1 hour 20 minutes, transfusion needs in 5.5 fold and hospitalization in 19 days; in comparison with open technique. Oncologic control based on surgical free margins, local control, overall survival and progression free survival after three years was higher when the resection was performed endoscopically. Functional status was enhanced and complications diminished by using endoscopic approach. Saving was estimated in $7 355.18 per patient. CONCLUSIONS: Endonasal endoscopic approach represents a safe, effective and economic procedure in selected patients with malignant sinonasal tumors and brain invasion.

No effect of desmopressin administration before kidney biopsy on the risk of major post-biopsy bleeding.

BACKGROUND/AIMS: The most important complication of kidney biopsy is bleeding, and it is unclear whether desmopressin is effective in preventing it. Thus, the study was conducted to compare post-biopsy bleeding with or without desmopressin prescription prior to percutaneous kidney biopsy. METHODS: In this single-centered, retrospective, and observational study, 3,018 adult patients who underwent kidney biopsy between January 1, 2003 and March 31, 2019 at our institute were recruited. Of these, 776 patients received desmopressin. To compare the differences in major bleeding events between patients administered and not administered with desmopressin, propensity score matching was performed. RESULTS: Before propensity score (PS) matching, it was observed that patients in the desmopressin group were significantly older (p<0.001) and had a higher blood pressure (p<0.001), higher serum creatinine (p<0.001), lower hemoglobin levels (p<0.001), and lower platelet counts (p=0.001) than those in the no-desmopressin group. Furthermore, the incidence of renal artery embolization was not significantly different between the two groups (p=0.077); however, blood transfusions occurred significantly more frequently in the desmopressin group (p<0.001). A comparison of the two groups after PS matching did not reveal any differences in the incidence of renal artery embolization (p=0.341), blood transfusion (p=0.579), and total major bleeding events (p=0.442). Furthermore, there was no difference in the incidence of perinephric hematoma on computed tomography or ultrasound (p=0.120). CONCLUSIONS: We do not recommend desmopressin administration before kidney biopsy.

Diferencia de edad entre cónyuges por nivel educativo en América Latina. El caso de Bolivia, Ecuador y Uruguay / Diferença de idade entre cônjuges por nível de escolaridade na América Latina. O caso de Bolívia, Equador e Uruguai / Spousal age difference by education in Latin America. The case of Bolivia, Ecuador and Uruguay

Resumen El objetivo del estudio es hacer un análisis descriptivo de la asociación entre la educación y la diferencia de edad entre los cónyuges en uniones de distinto sexo y conocer cómo ha evolucionado esta relación a lo largo de las cohortes en las últimas décadas a la luz del incremento del nivel educativo de la población en América Latina, en particular de las mujeres. Se hizo un análisis descriptivo utilizando muestras de rondas censales desde 1970 hasta 2010 de tres países de la región, Bolivia, Ecuador y Uruguay, seleccionando a hombres y a mujeres de 25 a 29 años de edad. Tanto en hombres como en mujeres, no se observa en general un descenso significativo de la diferencia etaria a lo largo de las cohortes. Mientras en las mujeres se observó una relación negativa entre la diferencia etaria entre cónyuges y nivel educativo, en los hombres se constató mayor heterogeneidad entre los países.

Resumo O objetivo do estudo é realizar uma análise descritiva da associação entre escolaridade e diferença de idade entre cônjuges em uniões de diferente sexo e como essa relação evoluiu ao longo das coortes nas últimas décadas em função do aumento da escolaridade da população da América Latina, especialmente para as mulheres. Foram utilizadas amostras de rodadas dos censos de 1970 a 2010 de três países da região − Bolívia, Equador e Uruguai −, selecionando homens e mulheres de 25 a 29 anos de idade. Para o total da amostra, não foi observada diminuição significativa na diferença de idade ao longo das coortes. Para as mulheres, verificou--se relação negativa entre a diferença de idade entre os cônjuges e a escolaridade. Para os homens, observou-se maior heterogeneidade entre os países.

Abstract The purpose of this study is to investigate the association between education and the age gap between spouses in heterosexual unions. The study also examines how this association has changed over time in different cohorts, especially among women, in the context of educational expansion in Latin America. The research used the data collected from census rounds conducted between 1970 and 2010 in Bolivia, Ecuador, and Uruguay. The sample included men and women aged between 25 to 29. The findings reveal that there was no significant decrease in the age difference throughout the cohorts for both men and women. However, a negative relationship was observed between the spousal age difference and educational level in women. On the other hand, men showed greater heterogeneity between countries.

Puntajes de propensión y estudios observacionales. Aplicaciones en investigación quirúrgica

El diseño ideal para estimar los efectos de intervenciones es un ensayo clínico con asignación aleatoria (AA), en los que esta AA a la intervención, equilibra características observadas y no observadas de los sujetos que componen los grupos en estudio. Si no se puede realizar AA, existe una alternativa para controlar sesgos, conocida como puntajes de propensión (PP). Los PP son útiles para estimar el efecto de una intervención o exposición sobre un resultado en estudios observacionales, especialmente cuando se estima la posibilidad que existan sesgos de confusión y selección debido a una asignación de tratamiento no aleatoria. Son una técnica de emparejamiento avanzada de variables de confusión como edad, sexo, etc., permitiendo que se puedan comparar pacientes de edad similar en grupos de intervención y de comparación. Esto, se puede complejizar si se decide agregar muchas variables al proceso de emparejamiento (edad, sexo, etnia, nivel educacional), puesto que será difícil encontrar coincidencias exactas para los sujetos. Entonces, los PP resuelven este problema de dimensionalidad comprimiendo factores relevantes en un solo puntaje, así, los pacientes con PP similares se comparan entre los grupos de intervención y comparación. El objetivo de este manuscrito fue generar un documento de estudio referente al uso de los PP y su rol en investigación quirúrgica.

The ideal design to estimate the effects of interventions, is a randomized clinical trial (RCT), in which the random allocation (RA) to the intervention allows balancing the observed and unobserved characteristics of the subjects that make up the study groups. In situations where RA cannot be performed, there is an alternative to bias control, which is known as propensity score (PS). This tool is useful for estimating the effect of an intervention or exposure on an outcome in observational studies, especially when it is estimated that confounding and selection biases may exist due to an unintended intervention RA. Is an advanced matching technique for confounding variables such as age, sex, etc., which allows patients of similar age to be compared in the intervention and comparison groups. This can become more complex if it is decided to add many variables to the matching process (age, sex, ethnicity, educational level), since it will be difficult to find exact matches for the subjects under study. PS then solves this dimensionality problem by compressing the relevant factors into a single score, such that patients with similar PS are compared between the intervention and comparison groups. The aim of this manuscript was to generate a study document referring to some issues of the use of PS in surgical research.

Long-term Mate Selection in Latin America: An Analysis of Personal Ads / Selección de Parejas a Largo Plazo en Latinoamérica: Un Análisis de Anuncios Personales

Abstract The present work aims to study which factors are relevant in long-term mate selection from a lonely-hearts personal advertisement sample of Spanish-speaking consumers of Cosmopolitan Magazine, Colombian Edition. We analyzed One thousand four hundred sixty-eight publications (made by 770 men and 698 women) using a coding system based on the theories of sexual strategies, genetic quality indicators, and the preferences classification used in personal ads studies. Initially, we found trends as a greater predilection for psychological attributes and a greater demand to require more traits than offering them. In addition, the cross-cultural pattern demonstrated that men prefer women's physical characteristics, while women require status/resources by men. Finally, men tended to be more selective in the age range of 36-45 years, while women's selectivity decreased with age. The results replicate many of the patterns found in investigations related to human sexual selection, also bring enlightenment about new preference dimensions to study in the future.

Resumen La presente investigación examina las preferencias de individuos que buscan emparejarse a largo plazo, por medio del análisis de anuncios de búsqueda de parejas, publicados por una muestra de usuarios hispanohablantes de la edición Colombiana de la Revista Cosmopolitan. Se revisaron 1468 publicaciones (de 770 hombres y 698 mujeres) utilizando un sistema de codificación construido a partir de la teoria de estrategias sexuales, indicadores de calidad genética y clasificaciones usadas en estudios de anuncios personales. Los usuarios reportaron una mayor atención por atributos psicológicos, además de una alta exigencia. Adicionalmente, los hombres solicitaron más características fisicas de las mujeres, y las mujeres más indicadores asociados al estatus y recursos de los hombres. Los hombres se mostraron más selectivos entre los 36 y los 45 anos, mientras que la selectividad de las mujeres disminuyó con la edad. Los resultados replican patrones encontrados en las investigaciones sobre emparejamiento sexual humano, y dan luces sobre nuevos dominios de preferencia para examinar en el futuro.

Ensino de leitura e escrita para alunos com deficiência intelectual baseado no Paradigma de Equivalência de Estímulos / Teaching reading and writing to students with intellectual disabilities based on stimulus equivalence instruction / Enseñar a leer y escribir a estudiantes con discapacidad intelectual basado en el Paradigma de Equivalencia de Estímulos

A formação de classes de estímulos equivalentes tem sido considerada um modelo para o estabelecimento de relações simbólicas, ou do significado, contribuindo para o ensino de leitura e escrita. O presente estudo teve como objetivo avaliar os efeitos de um módulo de ensino de um programa informatizado de leitura e escrita em crianças com deficiência intelectual matriculadas em uma escola regular. Participaram três alunos com idades entre 8 e 10 anos. O programa de ensino era aplicado na própria escola, duas a três vezes por semana, individualmente, com sessões de aproximadamente 35 minutos. Foi empregado uma avaliação geral de leitura e escrita antes e após o programa. Os resultados mostraram que quanto melhor o repertório de entrada, mais rapidamente os participantes avançaram no módulo e melhoraram seus repertórios de leitura e escrita. A realização dessa intervenção nas séries iniciais pode contribuir na aprendizagem de repertórios básicos de leitura e escrita.

The formation of stimulus equivalence classes has been considered a productive model of symbolic relations ­ or meaning ­ for teaching reading and writing. This study aimed to evaluate the effects of one module of a computerized reading and writing program for children with intellectual disabilities enrolled in a regular school. Three students aged between 8 and 10 participated in the study. The program was applied individually to each participant in the school premises across two to three weekly sessions of approximately 35 minutes each. General assessment was applied as a pre and post-test. The results showed that the better the participants' existing repertoires, the faster they advanced in the procedure and improved their reading and writing skills. Conducting this intervention in early school years can contribute to the process of leaning basic reading and writing

La formación de clases de estímulo equivalentes se ha considerado un modelo para el establecimiento de relaciones simbólicas, contribuyendo a la enseñanza de la lectura y escritura. El estudio tuvo como objetivo evaluar los efectos de un módulo didáctico de un programa computarizado de lectura y escritura en niños con discapacidad intelectual matriculados en una escuela regular. Participaron tres estu diantes de entre 8 y 10 años. El programa de enseñanza se aplicó en la escuela, de dos a tres veces por semana, de manera individual, con sesiones de aproximadamente 35 minutos. Se utilizó una evaluación general de lectura y escritura antes y después del programa. Los resultados mostraron que cuanto mejor era el repertorio de entrada, más rápido avanzaban los participantes en el módulo y mejoraban su repertorio. La realización de esta intervención en los grados iniciales puede contribuir al aprendizaje de los repertorios básicos de lectura y escritura.

Intencionalidad del embarazo y cuidados prenatales en Uruguay / Pregnancy intention and antenatal care services in Uruguay / Intencionalidade da gravidez e cuidado pré-natal no Uruguai

Resumen: Introducción: desde hace algunos años el número de embarazos no intencionales en Uruguay ronda el 40%; esta cifra es alta en comparación con otros países que también tienen baja fecundidad y da cuenta de las dificultades de acceso y uso eficaz de métodos anticonceptivos modernos. Además, varios estudios evidencian que los embarazos no intencionales están vinculados con cuidados prenatales insuficientes y peores desempeños de los recién nacidos respecto a los nacimientos resultantes de embarazos intencionales. Objetivo: analizar la asociación entre intencionalidad de los embarazos y los cuidados prenatales en Uruguay a partir del estudio de su incidencia sobre la captación temprana del embarazo y las prácticas no saludables durante la gestación (fumar y tomar alcohol). Método: se consideran los nacimientos no intencionales y a destiempo (no buscados en ese momento) como dos grupos de tratamiento y se comparan con el grupo de nacimientos intencionales. Se examina el efecto neto de la intencionalidad del embarazo sobre las prácticas de salud durante la gestación utilizando técnicas de Propensity Score Matching (PSM). Se utilizan datos provenientes de la Encuesta de Nutrición, Desarrollo Infantil y Salud (ENDIS), un estudio de panel que recoge información desde 2013 de madres con hijos de entre 0 y 3 años en hogares ubicados en localidades urbanas de Uruguay (mayores a 5.000 habitantes). Resultados: antes de realizar el emparejamiento por PSM, las diferencias entre grupos de intención de embarazos fueron significativas para captación temprana y haber fumado, mientras que haber bebido alcohol no se asoció a diferencias significativas entre grupos de intención de los embarazos.

Summary: Introduction: in Uruguay, the number of unintended pregnancies has been around 40% for several years. This is rather a high percentage if compared to other countries who also have low fertility rates and evidences difficulties in access to modern contraceptive methods or using them effectively. Likewise, several studies evidence unintended pregnancies are related to insufficient antenatal care services and worse outcome in the new-borns when compared to births resulting from intentional pregnancies. Objective: to study the relationship between pregnancy intentionality and antenatal care services in Uruguay, based on an analysis of its impact on the early engagement of pregnancies and non-healthy practices during pregnancy (smoking and alcohol consumption). Method: unintended and untimely births (not sought at that time) were included in the study as two treatment groups, and they are compared to the group of intentional births. The net effect of pregnancy intention on health practices during pregnancy was examined using the de Propensity Score Matching (PSM) techniques. We used data delivered by the Nutrition, Child Development and Health Survey, a panel study that has been collecting information from mothers of children between 0 and 3 years old who live in urban localities of Uruguay (with over 5,000 inhabitants) since 2013. Results: Prior to the PSM matching, the differences in early engagement and smoking were significant between pregnancy intention groups, whereas alcohol consumption was not associated to significant differences between pregnancy intention groups.

Resumo: Introdução: há anos, o número de gestações não intencionais no Uruguai gira em torno de 40%; este número é alto em comparação com outros países que também têm baixa fecundidade e explica as dificuldades de acesso e uso de métodos anticoncepcionais modernos. Além disso, diversos estudos mostram que a gravidez não intencional está associada ao pré-natal insuficiente e piores parâmetros do recém-nascido em comparação com o nascimento decorrente da gravidez intencional. Objetivos: analisar a associação entre intencionalidade da gravidez e assistência pré-natal no Uruguai, a partir do estudo de sua incidência na detecção precoce da gravidez e práticas não saudáveis durante a gravidez (tabagismo e etilismo). Método: os nascimentos não intencionais e prematuros (não desejados no momento) são considerados dois grupos de tratamento e comparados com o grupo de partos intencionais. O efeito líquido da intencionalidade da gravidez sobre as práticas de saúde durante a gravidez é examinado usando técnicas de correspondência de pontuação de propensão (PSM). São utilizados os dados da Pesquisa de Nutrição, Desenvolvimento Infantil e Saúde (ENDIS), um estudo de painel que coleta informações desde 2013 de mães com filhos de 0 a 3 anos em domicílios localizados em áreas urbanas do Uruguai (mais de 5.000 habitantes). Resultados: antes de realizar a comparação por PSM, as diferenças entre os grupos de intenção de gravidez foram significativas para recrutamento precoce e tabagismo, enquanto ter bebido álcool não foi associado a diferenças significativas entre os grupos de intenção de gravidez.

Aquisição de intraverbais em crianças com autismo: efeitos do pareamento de estímulos e respostas ecoicas / Intraverbal acquisition in autistic children: effects of stimulus pairing and echoic responses / Acquisition du comportement intraverbal chez des enfants autistes: effets de l'appariement des stimuli et des réponses échoïques / Adquisición de intraverbales en niños con autismo: efectos del emparejamiento de estímulos y respuestas ecoicas

Resumo O ensino de intraverbais para indivíduos com autismo tem sido realizado, principalmente, através de procedimentos que envolvem reforçamento diferencial. Recentemente, o procedimento de observação de pareamento de estímulos (SPOP) surgiu enquanto alternativa para verificar a emergência de repertórios verbais. O SPOP implica o pareamento de estímulos sem exigir outra resposta que a observação do pareamento. O ecoico tem sido apontado como facilitador na emergência de operantes verbais. O presente estudo comparou, com um delineamento de sondas múltiplas concorrentes com tratamento alternado adaptado, a eficácia do SPOP com um procedimento de apresentação contígua de estímulos com requisição de resposta ecoica na emergência de intraverbais em três crianças com autismo. Observou-se a eficácia do SPOP na indução de intraverbais e verificou-se o papel facilitador do ecoico. Discutem-se possíveis efeitos de interferência dos tratamentos, da extinção de respostas no contexto experimental e da utilização de reforçadores condicionados como parte do SPOP.

Abstract Intraverbals have been taught to individuals with autism primarily through procedures involving differential reinforcement. Recently, Stimulus Pairing Observation Procedure (SPOP) emerged as an alternative to verify the emergence of verbal repertoires. The SPOP consists in the simultaneous presentation of two stimuli and requires only the observation response by the participant. The echoic behavior had been pointed out as a mediator in the emergence of verbal operants. This study compared the efficacy of the SPOP and of a contiguous stimulus presentation procedure with an echoic response requirement in emergence of intraverbals in three children with autism by using a concurrent multiple probe design with an adapted alternating treatment. The results showed the SPOP's efficacy for intraverbals induction and suggested a facilitating role of the echoic. A possible carry-over effect between treatments, extinction in the experimental context and the use of conditioned reinforcers in SPOP are discussed.

Résumé L'enseignement de l'intraverbal chez des individus autistes a été principalement réalisé avec des procédures impliquant le renforcement différentiel. Plus récemment, la Procédure d'Observation de Paires des Stimuli (SPOP en anglais) s'est imposée comme alternative pour vérifier l'émergence de répertoires verbaux. Le SPOP implique l'appariement des stimuli sans exiger d'autre réponse que l'observation des paires. Par ailleurs, l'échoïque a été signalé comme facilitateur de l'émergence d'opérants verbaux. Nôtre étude a comparé, avec un plan expérimental de sondes multiples concurrents et traitements alternés adapté, l'efficacité du SPOP en comparaison à une procédure de présentation du stimulus contigu avec réponse échoïque dans l'émergence du comportement intraverbal chez trois enfants autistes. Nous avons pu observer l'efficacité du SPOP dans l'induction de l'intraverbal ainsi qu'un rôle facilitateur de l'échoïque. Nous discutons les effets possibles de l'interférence entre traitements, de l'extinction de réponses dans le contexte expérimental, et de l'emploi de renforçateurs conditionnés dans le cadre du SPOP.

Resumen La enseñanza de intraverbales a autistas se ha realizado principalmente a través de procedimientos con refuerzo diferencial. Más recientemente, el procedimiento de observación de emparejamiento de estímulo (POEE) surgió como alternativa para verificar la emergencia de repertorios verbales. El POEE implica el emparejamiento de estímulos, sin exigir otra respuesta que la observación del emparejamiento. El ecoico se considera facilitador en la emergencia de operantes verbales. Este estudio comparó, desde un delineamiento de sondas múltiples con tratamiento alternado adaptado, la eficacia del POEE con un procedimiento de presentación de estímulo contiguo solicitante de respuesta ecoica en la emergencia de intraverbales en tres niños autistas. El POEE fue eficaz en la inducción de intraverbales, y el ecoico tuvo un papel facilitador. Se discuten los posibles efectos de interferencia de los tratamientos, de la extinción de respuestas en el contexto experimental y de la utilización de reforzadores condicionados como parte del POEE.

Diferencias en la conducta de emparejamiento entre mujeres jóvenes universitarias de Santiago de Chile en relación con el consumo de píldoras anticonceptivas orales / Differences in mating behavior among university young women of Santiago de Chile in relation to the consumption of oral contraceptive pills

Durante los últimos años en Chile se ha detectado una masificación en el uso de anticonceptivos orales. Sin embargo, en Chile y al igual que en casi todos los países latinoamericanos prácticamente no se han investigado sus implicancias sobre la conducta humana. Específicamente, este estudio evaluó el impacto del uso de estos anticonceptivos sobre la conducta de emparejamiento en un grupo de 164 mujeres jóvenes universitarias, con una media de edad igual a 19 años y provenientes de cuatro universidades chilenas. Para ello se utilizó la adaptación chilena del Cuestionario de Componentes del Valor de Pareja que está compuesto por 22 ítems que se responden en una escala Likert de siete valores. Los resultados señalan diferencias entre las mujeres que consumen píldoras anticonceptivas (PA) y las que no lo hacen. Las consumidoras presentan los mayores valores del índice general del cuestionario sobre los componentes del valor de pareja y las subescalas de historia de relaciones de pareja, apreciación desde el sexo opuesto y apariencia. Estos resultados indican que las mujeres consumidoras de la PA se autoperciben y creen que el sexo contrario las evalúa como atractivas y muestran una vida sexual más diversificada, no mostrando diferencias en los otros aspectos relevantes para el valor de pareja no vinculados centralmente al atractivo físico. En definitiva, los resultados parecen indicar que el consumo de anticonceptivos hormonales no modifica la conducta social y parental de las mujeres, aunque su uso parece estar asociado con una mayor autopercepción de atractivo y mayor diversidad sexual.

Oral contraceptives, also known as birth control pills (PAs from now on), have been available on the world market for five decades. At present, the use of PA is massifier worldwide, being consumed by more than 100 million women on the planet. In recent years, in Latin America has been detected a dramatic increase in the use of oral contraceptives, and Chile is not the exception. In this sense, it is probable that the increase in the consumption of PAs in Chile is linked to the increase of women who decide to pursue higher studies and to develop professional careers. Concurrently, a wide field of research has been focused on the physiological and psychological effect of the consumption of oral contraceptives on human behavior, being mating behavior one of the main topics of research. However, in Chile as in most Latin American countries there is a lack of studies on the implications of the consumption of oral contraceptives on human behavior. In the present study, we investigated in a group of 164 university young women (Mean ± Standard Deviation: 19.27± 2.88 years) of Chile the impact of the use of oral contraceptives on mating behavior. Accordingly, we have applied a validated psychometric test to assessed mate value, one of the more relevant components of mating behavior i.e., the Mate Value Questionnaire. Mate value can be defined as a construct that incorporates a number of physical, psychological, and social dimensions that are related to an individual's ability to find, attract, and successfully retain a partner. This questionnaire is composed by 22 items and 7 subscales that are answered in a Likert Scale of 7 values. The Mate Value Questionnaire showed a high reliability (α = .85). According with previous studies that showed a decrease in sexual satisfaction and desire on women that consume oral contraceptives, we predicted a decrease of mating behavior and, then, a decrease on Mate Value for those women that use oral contraceptives. This effect was expected for all subscales of this questionnaire with the exception of relationship history subscale since women that consume oral contraceptives reported to have more diverse sexual partners on previous studies. The results show differences between women who use oral contraceptives (n = 87 women: 19.60 ± 2.89 years) in comparison to those who do not (n = women: 18.90 ± 2.84 years). However, the differences were, in general, opposed to our expectations being the consumers of oral contraceptives who presented the highest values of the general index of the Mate Value Questionnaire, and, concretely, for the subscales of relationship history, views of the opposite sex, and looks. In addition, we have failed into found any differences between groups in subscales that were not associated to physical appearance, such as wealth, sociality and fear of failure. The results suggest that the use of hormonal contraceptives does not modify the social and parental behavior of the women, although their use seems to be associated with a greater self-perception of attractiveness and greater diversity in sexual life. This study provides new information that will increase the understanding and discussion about the hypothetical effect that would or would not, the consumption of the PA on the pairing behavior. It is important to point out that the field of research on changes in the sexual preferences of women, derived from hormonal states, is in an important discussion process. Therefore, we believe that it is critical to carry out research in the future in order to elucidate the real robustness of this phenomenon, improving our understanding about the behavioral effects of consuming oral contraceptives.

Fiabilidad de la versión informatizada del Test de Figuras Conocidas 20 (MFF-20) / Reliability of the computerised version of the Matching Familiar Figures Test (MFF-20)

El constructo de impulsividad-reflexividad hace referencia a un estilo cognitivo. Se han propuesto dos dimensiones a evaluar, impulsivos, cuando se generan respuestas con gran número de errores y corto tiempo de latencia y reflexivos, cuando hay bajo número de errores y alto tiempo de latencia. El objetivo de este estudio es comparar los coeficientes de fiabilidad obtenidos de la aplicación del Test de Emparejamiento de Figuras Conocidas (MFF-20) en una versión en formato ordenador (MFF-O) contra una versión en formato papel (MFF-P). Se obtuvieron tres muestras independientes, con participantes entre 6 a 11 años de edad con un tipo de muestreo por conveniencia. La primera muestra fueron 50 niños que se evaluaron inicialmente con la versión MFF-P y 6 meses después con el MFF-O. La segunda muestra fueron 52 niños que se evaluaron con la versión de MFF-P y después de 6 meses con la versión de MFF-P. Posteriormente se procedió a evaluar a una tercera muestra independiente de 298 niños con la versión de MFF-O. Los resultados muestran la comparación entre las condiciones y las propiedades psicométricas de la versión en ordenador. Se concluye que la versión del MFF-20 en ordenador cuenta con adecuada fiabilidad y propiedades psicométricas, las cuales son similares a la versión del MFF 20 en papel.

The impulsivity-reflexivity construct refers to a cognitive style. Two dimensions have been proposed for their evaluation: Impulsivity, when responses are generated with a number of errors and short latency period, and reflexivity, when responses are generated with a few mistakes and long latency time. This study aims to compare the reliability coefficients obtained by applying computerised version (MFF-O) of the Matching Figures Test-20 (MFF-20) against a paper-based version (MFF-P). Three independent samples were obtained with participants aged from 6 to 11 years. The first sample consisted of 50 children who were evaluated with the MFF-P version, and 6 months later they were evaluated with the MFF-O version. The second sample included 52 children who were evaluated with the MFF-P version, and then re-evaluated with the same version 6 months later. Subsequently, a third sample including 298 children was evaluated with the MFF-O. The results showed a comparison between the psychometric properties and conditions of the computer-based version. It was concluded conclude that the computer-based MFF-20 version has adequate reliability and psychometric properties that are similar to the paper-based MFF-P version.