RESUMO
BACKGROUND: Wide area transepithelial sampling with three-dimensional computer-assisted analysis (WATS3D) is an adjunct to the standard random 4-quadrant forceps biopsies (FB, "Seattle protocol") that significantly increases the detection of Barrett's esophagus (BE) and associated neoplasia in patients undergoing screening or surveillance. AIMS: To examine the cost-effectiveness of adding WATS3D to the Seattle protocol in screening patients for BE. METHODS: A decision analytic model was used to compare the effectiveness and cost-effectiveness of two alternative BE screening strategies in chronic gastroesophageal reflux disease patients: FB with and without WATS3D. The reference case was a 60-year-old white male with gastroesophageal reflux disease (GERD). Effectiveness was measured by the number needed to screen to avert one cancer and one cancer-related death, and quality-adjusted life years (QALYs). Cost was measured in 2019 US$, and the incremental cost-effectiveness ratio (ICER) was measured in $/QALY using thresholds for cost-effectiveness of $100,000/QALY and $150,000/QALY. Cost was measured in 2019 US$. Cost and QALYs were discounted at 3% per year. RESULTS: Between 320 and 337 people would need to be screened with WATS3D in addition to FB to avert one additional cancer, and 328-367 people to avert one cancer-related death. Screening with WATS3D costs an additional $1219 and produced an additional 0.017 QALYs, for an ICER of $71,395/QALY. All one-way sensitivity analyses resulted in ICERs under $84,000/QALY. CONCLUSIONS: Screening for BE in 60-year-old white male GERD patients is more cost-effective when WATS3D is used adjunctively to the Seattle protocol than with the Seattle protocol alone.
Assuntos
Esôfago de Barrett/patologia , Diagnóstico por Computador/economia , Detecção Precoce de Câncer/economia , Células Epiteliais/patologia , Mucosa Esofágica/patologia , Neoplasias Esofágicas/patologia , Refluxo Gastroesofágico/patologia , Custos de Cuidados de Saúde , Esôfago de Barrett/economia , Esôfago de Barrett/mortalidade , Esôfago de Barrett/terapia , Biópsia/economia , Simulação por Computador , Análise Custo-Benefício , Técnicas de Apoio para a Decisão , Neoplasias Esofágicas/economia , Neoplasias Esofágicas/mortalidade , Neoplasias Esofágicas/terapia , Refluxo Gastroesofágico/economia , Refluxo Gastroesofágico/mortalidade , Refluxo Gastroesofágico/terapia , Humanos , Imageamento Tridimensional/economia , Masculino , Pessoa de Meia-Idade , Modelos Econômicos , Valor Preditivo dos Testes , Anos de Vida Ajustados por Qualidade de Vida , Fatores de Risco , Resultado do TratamentoAssuntos
Fósseis , Imageamento Tridimensional , Disseminação de Informação/legislação & jurisprudência , Publicação de Acesso Aberto/legislação & jurisprudência , Paleontologia/métodos , Paleontologia/organização & administração , Animais , Carnivoridade , Guias como Assunto , Imageamento Tridimensional/economia , Internet , Bibliotecas Digitais/economia , Bibliotecas Digitais/legislação & jurisprudência , Museus/economia , Publicação de Acesso Aberto/economia , Paleontologia/economia , Paleontologia/legislação & jurisprudência , Crânio/anatomia & histologiaRESUMO
BACKGROUND: Multi-b diffusion-weighted hyperpolarized-gas MRI measures pulmonary airspace-enlargement using apparent diffusion coefficients (ADCs) and mean-linear-intercepts (Lm ). PURPOSE: To develop single-breath 3D multi-b diffusion-weighted 3 He and 129 Xe MRI using k-space undersampling. Rapid, cost-efficient, single-breath acquisitions may facilitate clinical translation. STUDY TYPE: Prospective. SUBJECTS: We evaluated 12 participants, including nine subjects (mean age = 69 ± 9) who were included in the retrospective experiment and three chronic pulmonary obstruction disease (COPD) patients (mean age = 81 ± 6) who participated in the prospective study. FIELD STRENGTH: A whole-body 3 T 2D/3D fast gradient recall echo (FGRE) sequence. ASSESSMENT: Hyperpolarized 3 He/129 Xe MRI, spirometry, plethysmography computed tomography (CT). We evaluated 129 Xe ADC/morphometry estimates by retrospectively undersampling previously acquired fully sampled multibreath, multi-b diffusion-weighted data. Next, we prospectively evaluated the feasibility of accelerated (AF = 7) 3 He MRI static-ventilation/T2 * (extra short-TE, b = 0 image) and ADC/morphometry (five b-values) maps using a single gas-dose and 16-second breath-hold. To conservatively evaluate cost-improvement, we compared total costs of single vs. multiple 129 Xe doses. STATISTICAL TESTS: Multivariate analysis of variance, independent t-tests and voxel-by-voxel basis difference test. RESULTS: For the retrospectively undersampled 129 Xe data, a nonsignificant mean difference for ADC/Lm of 14%/12%, 12%/8%, and 11%/9% was observed (all, P > 0.4) between the fully sampled and accelerated data for the never-smoker, COPD, and alpha-1 antitrypsin deficiency (AATD) groups, respectively. The control never-smoker group had significantly lower ADC (P < 0.001) and Lm (P < 0.001) than the COPD/AATD group for both fully sampled and accelerated data. For the prospectively acquired 3 He MRI data, static-ventilation, T2 *, ADC, and morphometry maps were acquired using a single 16-second breath-hold scan and single gas dose. Accelerated imaging resulted in cost savings of ~$US 1000/patient, a conservative estimate based on 129 Xe MRI dose savings (single vs. five doses). DATA CONCLUSION: This is a proof-of-concept demonstration of accelerated (7×) morphometry that shows that less cost- and time-efficient multibreath methods that lead to variability and patient fatigue may be avoided in the future. LEVEL OF EVIDENCE: 2 Technical Efficacy: Stage 5 J. Magn. Reson. Imaging 2018.
Assuntos
Hélio , Imageamento Tridimensional/métodos , Isótopos , Imageamento por Ressonância Magnética/métodos , Doença Pulmonar Obstrutiva Crônica/diagnóstico por imagem , Isótopos de Xenônio , Idoso , Idoso de 80 Anos ou mais , Difusão , Feminino , Gases , Humanos , Imageamento Tridimensional/economia , Imageamento por Ressonância Magnética/economia , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Gases Nobres , Pletismografia , Estudo de Prova de Conceito , Estudos Prospectivos , Reprodutibilidade dos Testes , Estudos Retrospectivos , Espirometria , Tomografia Computadorizada por Raios X , XenônioAssuntos
Monitoramento Ambiental , Mapeamento Geográfico , Imageamento Tridimensional , Rios , Sepultamento/legislação & jurisprudência , Cidades , Planejamento em Desastres , Monitoramento Ambiental/economia , Recuperação e Remediação Ambiental , Inundações , Humanos , Imageamento Tridimensional/economia , Índia , Reforma Urbana , Poluição da Água/análiseRESUMO
BACKGROUND: Periprosthetic fractures (PPF) present a common cause for revision surgery after arthroplasty. The choice of performing either an osteosynthesis or revision arthroplasty depends on the orthopedic implant anchored and loosening. Standard diagnostics include x-ray imaging. CT is usually performed to confirm implant loosening in case of ambiguous diagnosis on standard x-ray imaging. This study aimed to examine the role of CT as a diagnostic modality and its implications for treatment planning and outcome. METHODS: Patients treated for PPF from January 2010 to February 2018 were included. X-ray and CT reports were analyzed to assess implant loosening. The planning for surgery and the final surgical treatment were evaluated. In addition, patient characteristics were analyzed and compared between patients with and without additional CT as a preoperative diagnostic procedure. RESULTS: Seventy-five patients were eligible for the study. X-ray imaging was performed in 90.7% of cases. CT was performed in 60% of the cases as part of the preoperative diagnostic. A clear statement on implant stability or loosening could not be made in 69.1% after X-ray imaging and in 84.4% following CT imaging. Revision arthroplasty for loosened femoral prosthesis components was necessary in 40% of cases. No difference could be determined comparing patients with X-ray imaging to those with X-ray and additional CT. In both groups, operative treatment did not deviate from the preoperative planning. DISCUSSION: In two thirds of the conventional radiographic findings, no reliable evaluation of implant loosening was possible in femoral PPFs. Intriguingly, additional CT did not improve the evaluation of implant loosening. Nonetheless, CT scans are often performed if loosening assessment is unclear on regular radiographs. This fact can explain the bias CT results in comparison to regular radiography. However, software-supported CT diagnosis could help to adequately answer the question of loosened implants in PPF in the near future. Since the diagnosis of fracture and their morphology assessment is currently adequately performed using X-rays, CT shall not be considered as the gold standard.
Assuntos
Fraturas do Fêmur/diagnóstico por imagem , Fraturas Periprotéticas/diagnóstico por imagem , Cuidados Pré-Operatórios/métodos , Falha de Prótese , Idoso , Idoso de 80 Anos ou mais , Artroplastia de Quadril/efeitos adversos , Artroplastia de Quadril/instrumentação , Artroplastia do Joelho/efeitos adversos , Artroplastia do Joelho/instrumentação , Feminino , Fraturas do Fêmur/etiologia , Fraturas do Fêmur/cirurgia , Prótese de Quadril/efeitos adversos , Humanos , Imageamento Tridimensional/efeitos adversos , Imageamento Tridimensional/economia , Imageamento Tridimensional/métodos , Prótese do Joelho/efeitos adversos , Masculino , Pessoa de Meia-Idade , Planejamento de Assistência ao Paciente/economia , Fraturas Periprotéticas/etiologia , Fraturas Periprotéticas/cirurgia , Cuidados Pré-Operatórios/efeitos adversos , Cuidados Pré-Operatórios/economia , Reoperação/métodos , Estudos Retrospectivos , Tomografia Computadorizada por Raios X/efeitos adversos , Tomografia Computadorizada por Raios X/economia , Tomografia Computadorizada por Raios X/métodosRESUMO
PURPOSE: In many medical schools, the study of Anatomy is becoming increasingly theoretical owing to the difficulty of having human body parts available, rather than offering the students the possibility of a more realistic and practical approach. We developed a project where we use a 3D printer to produce models of the human skull bones, with high quality and quantity to satisfy the needs for Anatomy classes and to be available for request to study at home. METHODS: We selected regular and well-shaped bones of the head upon which we based the 3D models. These bones were scanned using a 64-channel Computed Tomography (high-resolution volumetric acquisition) and the resulting images were then processed with a segmentation software to isolate and reconstruct the structures of interest. The final digital three-dimensional objects were converted into a printable file that the 3D printer could read. We used two filament extrusion type 3D printers, the Prusa i3 and the Zortrax M200. RESULTS: We have printed successfully several models of the skull bones, such as the temporal, occipital, and sphenoid. All the models have obtained good anatomical detail, thus demonstrating the practicality of this technology. Key aspects of the CT image post-processing are discussed. The production process is cost-effective and technically accessible. CONCLUSIONS: These results confirm the potential of 3D printing to create more complex models (e.g. regional, vascular, nervous system structures) that would allow a similar experience compared with a dissection.
Assuntos
Anatomia/educação , Educação de Graduação em Medicina/métodos , Modelos Anatômicos , Impressão Tridimensional/economia , Crânio/anatomia & histologia , Análise Custo-Benefício , Dissecação , Educação de Graduação em Medicina/economia , Humanos , Imageamento Tridimensional/economia , Imageamento Tridimensional/instrumentação , Impressão Tridimensional/instrumentação , Faculdades de Medicina/economia , Crânio/diagnóstico por imagem , Software , Tomografia Computadorizada por Raios X/economia , Tomografia Computadorizada por Raios X/instrumentaçãoRESUMO
3D imaging for body measurements is regularly used for design of garments and ergonomic products. The development of low-cost 3D scanners provided an opportunity to extend the use of 3D imaging to the health sector. We developed and tested the AutoAnthro System, the first mobile, low-cost, full-body, 3D imaging system designed specifically for child anthropometry. This study evaluated the efficiency, invasiveness, and user experience of the AutoAnthro System. We used a mixed-methods, collaborative approach that included a quantitative time-motion study and qualitative interviews of anthropometrists. For cooperative children, anthropometrists considered the use of 3D imaging an easy, "streamlined experience," but with uncooperative children, anthropometrists reported that capturing a good quality scan was out of their control. The mean time to complete a full set of scans was 68 s (standard deviation [SD] 29), compared with 135 s (SD 22) for a set of manual measurements (stature, head circumference, and arm circumference). We observed that crying was more common during manual measurement, and anthropometrist interviews confirmed that 3D imaging was less stressful for children than manual measurement. In a previous publication, we showed the potential of 3D imaging to produce reliable and accurate measurements. In this study, we found that anthropometrists were not ready to abandon manual equipment for 3D scanners because of difficulty in measuring uncooperative children. Revising the AutoAnthro System to address anthropometrists' concerns on capturing good quality scans of uncooperative children should help to facilitate widespread use of 3D imaging for child anthropometry.
Assuntos
Antropometria/instrumentação , Antropometria/métodos , Imageamento Tridimensional/instrumentação , Imageamento Tridimensional/métodos , Pré-Escolar , Feminino , Humanos , Imageamento Tridimensional/economia , Lactente , Masculino , Reprodutibilidade dos TestesAssuntos
Arte , Empreendedorismo , Imageamento Tridimensional/métodos , Software , Gravação em Vídeo/métodos , Gravação em Vídeo/normas , Algoritmos , Simulação por Computador , Humanos , Imageamento Tridimensional/economia , Estimulação Luminosa , Software/economia , Interface Usuário-Computador , Gravação em Vídeo/economiaRESUMO
BACKGROUND: Three-dimensional view in laparoscopic general, gynaecologic and urologic surgery is an efficient, safe and sustainable innovation. The present paper is an extract taken from a full health technology assessment report on three-dimensional vision technology compared with standard two-dimensional laparoscopic systems. METHODS: A health technology assessment approach was implemented in order to investigate all the economic, social, ethical and organisational implications related to the adoption of the innovative three-dimensional view. With the support of a multi-disciplinary team, composed of eight experts working in Italian hospitals and Universities, qualitative and quantitative data were collected, by means of literature evidence, validated questionnaire and self-reported interviews, applying a final MCDA quantitative approach, and considering the dimensions resulting from the EUnetHTA Core Model. RESULTS: From systematic search of literature, we retrieved the following studies: 9 on general surgery, 35 on gynaecology and urology, both concerning clinical setting. Considering simulated setting we included: 8 studies regarding pitfalls and drawbacks, 44 on teaching, 12 on surgeons' confidence and comfort and 34 on surgeons' performances. Three-dimensional laparoscopy was shown to have advantages for both the patients and the surgeons, and is confirmed to be a safe, efficacious and sustainable vision technology. CONCLUSIONS: The objective of the present paper, under the patronage of Italian Society of Endoscopic Surgery, was achieved in that there has now been produced a scientific report, based on a HTA approach, that may be placed in the hands of surgeons and used to support the decision-making process of the health providers.
Assuntos
Imageamento Tridimensional , Laparoscopia/métodos , Custos e Análise de Custo , Percepção de Profundidade , Humanos , Imageamento Tridimensional/economia , Itália , Laparoscopia/economia , Duração da Cirurgia , Segurança do Paciente , Complicações Pós-Operatórias , Desempenho Psicomotor , Avaliação da Tecnologia BiomédicaRESUMO
The aim of this study is to evaluate the cost-effectiveness of an extended use of 3D non-fluoroscopic mapping systems (NMSs) during paediatric catheter ablation (CA) in an adult EP Lab. This study includes 58 consecutive patients (aged between 8 and 18) who underwent CA from March 2005 to February 2015. We compare the fluoroscopy data of two groups: group I, patients who underwent CA from 2005 to 2008 using only fluoroscopy, and group II, patients who underwent CA from 2008 to 2015 performed also using NMSs. Two cost-effectiveness analyses were carried out: the first method was based on the alpha value (AV), and the second one was based on the value of a statistical life (VSL). For both methods, a children's correction factor was also considered. The reduction cost estimated from all these methods was compared to the real additional cost of using NMSs. The use of an NMS during a CA procedure has led to an effective dose reduction (ΔE) of 2.8 milli-Sievert. All presented methods are based on parameters with a wide range of values. The use of an NMS, applying directly AV values or VSL values, is not cost-effective for most countries. Only considering the children's correction factor, the CA procedure using an NMS seems to be cost-effective. The cost-effectiveness of a systematic use of NMSs during CA procedures in children and teenagers remains a challenging task. A positive result depends on which value of AV or VSL is considered and if the children's correction factor is applied or not.
Assuntos
Ablação por Cateter/métodos , Fluoroscopia/economia , Imageamento Tridimensional/economia , Adolescente , Mapeamento Potencial de Superfície Corporal/economia , Ablação por Cateter/economia , Criança , Análise Custo-Benefício , Feminino , Fluoroscopia/métodos , Humanos , Masculino , Exposição à Radiação/prevenção & controleRESUMO
Conventional two-dimensional (2D) ultrasound imaging is a powerful diagnostic tool in the hands of an experienced user, yet 2D ultrasound remains clinically underutilized and inherently incomplete, with output being very operator dependent. Volumetric ultrasound systems can more fully capture a three-dimensional (3D) region of interest, but current 3D systems require specialized transducers, are prohibitively expensive for many clinical departments, and do not register image orientation with respect to the patient; these systems are designed to provide improved workflow rather than operator independence. This work investigates whether it is possible to add volumetric 3D imaging capability to existing 2D ultrasound systems at minimal cost, providing a practical means of reducing operator dependence in ultrasound. In this paper, we present a low-cost method to make 2D ultrasound systems capable of quality volumetric image acquisition: we present the general system design and image acquisition method, including the use of a probe-mounted orientation sensor, a simple probe fixture prototype, and an offline volume reconstruction technique. We demonstrate initial results of the method, implemented using a Verasonics Vantage research scanner.
Assuntos
Imageamento Tridimensional/instrumentação , Imageamento Tridimensional/métodos , Ultrassonografia/instrumentação , Ultrassonografia/métodos , Humanos , Imageamento Tridimensional/economia , Transdutores/economia , Ultrassonografia/economiaRESUMO
OBJECTIVE: The purpose of this study was to evaluate the cost-effectiveness of the addition of annual screening tomosynthesis to 2D digital mammography alone for women beginning at 40 years old and to determine differences for age decade subgroups. MATERIALS AND METHODS: Decision-tree analysis comparing annual tomosynthesis versus 2D mammography alone from a federal payer perspective and lifetime horizon was created from published multiinstitutional data, published institutional data, literature values, and Medicare reimbursement rates. Cost-effectiveness was calculated through incremental cost-effectiveness ratios and net monetary benefit calculations. Sensitivity analyses were performed to determine the implication of different variables including changes in recall rate and disutility for false-positives. RESULTS: Base-case analysis showed an incremental cost per quality-adjusted life year gained for tomosynthesis over 2D alone for all ages (≥ 40 years old) of $20,230, 40- to 49-year-old subgroup of $20,976, 50- to 59-year-old subgroup of $49,725, 60- to 69-year-old subgroup of $44,641, and ≥ 70-year-old subgroup of $82,500. Net monetary benefit per decade in the 40- to 49-year-old subgroup was $1,598, 50- to 59-year-old subgroup of $546, 60- to 69-year-old subgroup of $535, and ≥ 70-year-old subgroup of $501. Tomosynthesis was the better strategy in 63.2% of the iterations according to probabilistic sensitivity analysis. CONCLUSION: Addition of annual screening tomosynthesis to 2D mammography beginning at the age of 40 years was cost-effective compared with 2D mammography alone in our analysis. Three times greater net monetary benefits were found in women 40-49 years old compared with those 50-59 years old.
Assuntos
Neoplasias da Mama/diagnóstico por imagem , Neoplasias da Mama/economia , Mamografia/economia , Adulto , Idoso , Árvores de Decisões , Detecção Precoce de Câncer/economia , Feminino , Humanos , Imageamento Tridimensional/economia , Programas de Rastreamento/economia , Pessoa de Meia-Idade , Intensificação de Imagem Radiográfica/economiaRESUMO
INTRODUCTION: Development of radiation technology provides new opportunities for the treatment of prostate cancer, but little is known about the costs of novel technologies. AIM: The aim of this analysis was to compare the costs of conventional three-dimensional radiation therapy to normal and hypofractionated intensity-modulated radiation therapy for the treatment of localized prostate cancer. METHOD: The cost-analysis was performed based on the data of a Hungarian oncology center from health care provider's perspective. Irradiation time was assessed from the data of 100 fractions delivered in 20 patients. Unit costs for each component were calculated based on actual costs retrieved from the accounting system of the oncology center. RESULTS: Average treatment delivery times were 14.5 minutes for three-dimensional radiation therapy, 16.2 minutes for intensity-modulated radiation therapy with image-guided and 14 minutes without image-guided method. Expected mean cost of patients undergoing conventional three-dimensional radiation therapy, normal and hypofractionated intensity-modulated radiation therapy were 619 000 HUF, 933 000 HUF and 692 000 HUF, respectively. CONCLUSIONS: Although normal and hypofractionated intensity-modulated radiation therapies have already been proven to be cost-effective, current reimbursement rates do not encourage healthcare providers to use the more effective therapy techniques.
Assuntos
Efeitos Psicossociais da Doença , Custos de Cuidados de Saúde , Neoplasias da Próstata/economia , Neoplasias da Próstata/radioterapia , Radioterapia Guiada por Imagem/economia , Radioterapia de Intensidade Modulada/economia , Idoso , Análise Custo-Benefício , Fracionamento da Dose de Radiação , Humanos , Hungria , Imageamento Tridimensional/economia , Masculino , Planejamento da Radioterapia Assistida por Computador/economia , Radioterapia Conformacional/economia , Radioterapia Guiada por Imagem/métodos , Radioterapia de Intensidade Modulada/métodos , Tomografia Computadorizada por Raios X , Resultado do TratamentoRESUMO
PURPOSE: To evaluate the effectiveness of combined biennial digital mammography and tomosynthesis screening, compared with biennial digital mammography screening alone, among women with dense breasts. MATERIALS AND METHODS: An established, discrete-event breast cancer simulation model was used to estimate the comparative clinical effectiveness and cost-effectiveness of biennial screening with both digital mammography and tomosynthesis versus digital mammography alone among U.S. women aged 50-74 years with dense breasts from a federal payer perspective and a lifetime horizon. Input values were estimated for test performance, costs, and health state utilities from the National Cancer Institute Breast Cancer Surveillance Consortium, Medicare reimbursement rates, and medical literature. Sensitivity analyses were performed to determine the implications of varying key model parameters, including combined screening sensitivity and specificity, transient utility decrement of diagnostic work-up, and additional cost of tomosynthesis. RESULTS: For the base-case analysis, the incremental cost per quality-adjusted life year gained by adding tomosynthesis to digital mammography screening was $53 893. An additional 0.5 deaths were averted and 405 false-positive findings avoided per 1000 women after 12 rounds of screening. Combined screening remained cost-effective (less than $100 000 per quality-adjusted life year gained) over a wide range of incremental improvements in test performance. Overall, cost-effectiveness was most sensitive to the additional cost of tomosynthesis. CONCLUSION: Biennial combined digital mammography and tomosynthesis screening for U.S. women aged 50-74 years with dense breasts is likely to be cost-effective if priced appropriately (up to $226 for combined examinations vs $139 for digital mammography alone) and if reported interpretive performance metrics of improved specificity with tomosynthesis are met in routine practice.
Assuntos
Neoplasias da Mama/diagnóstico por imagem , Detecção Precoce de Câncer/métodos , Imageamento Tridimensional , Mamografia , Intensificação de Imagem Radiográfica , Idoso , Idoso de 80 Anos ou mais , Análise Custo-Benefício , Detecção Precoce de Câncer/economia , Feminino , Humanos , Imageamento Tridimensional/economia , Mamografia/economia , Pessoa de Meia-Idade , Intensificação de Imagem Radiográfica/economiaRESUMO
OBJECTIVES: To compare two-dimensional (2D) and three-dimensional (3D) transvaginal ultrasound with magnetic resonance imaging (MRI) as the gold standard in assessment of parametrial infiltration of cervical cancer and to determine if all parts of the cervix are equally assessable with ultrasound. METHODS: Patients with macroscopically evident and histologically confirmed cervical cancer were staged using International Federation of Gynecology and Obstetrics (FIGO) criteria and underwent MRI and 2D and 3D ultrasound examination before treatment. When assessing parametrial infiltration with 3D ultrasound and MRI, the cervix was (virtually) divided into three cylinders (cranial, middle and caudal) of equal size and each cylinder was then divided into six sectors in a clockwise manner following a consensus between radiologists and ultrasound examiners. The presence and the extent of parametrial invasion were recorded for each sector. Results of 2D ultrasound, 3D ultrasound and MRI were compared and reported in terms of percentage agreement and kappa value. RESULTS: A total of 29 consecutive patients were included in the study. The percentage agreement between 2D ultrasound and MRI in assessing parametrial infiltration (yes or no) was 76% (kappa, 0.459) and that between 3D ultrasound and MRI was 79% (kappa, 0.508). The results of 2D ultrasound showed the following agreement with those of MRI: 90% for the ventral parametrium (kappa, 0.720), 72% for the right lateral parametrium (kappa, 0.494), 69% for the left lateral parametrium (kappa, 0.412) and 58.5% for the dorsal parametrium (kappa, 0.017). The results of 3D ultrasound showed the following agreement with those of MRI: 62.5% for the ventral parametrium (kappa, 0.176), 81% for the right lateral parametrium (kappa, 0.595), 70% for the left lateral parametrium (kappa, 0.326) and 52% for the dorsal parametrium (kappa, 0.132). The best agreement between 3D ultrasound and MRI was for the middle cervical cylinder (76%; kappa, 0.438) and the poorest agreement was for the caudal cylinder (42%; kappa, 0.125). CONCLUSION: The results of 2D and 3D ultrasound showed similar moderate agreement with MRI; 2D and 3D ultrasound examinations are less costly and more readily available than MRI and should be considered in the preoperative work-up for cervical cancer.
Assuntos
Imageamento Tridimensional/métodos , Imageamento por Ressonância Magnética/métodos , Neoplasias do Colo do Útero/diagnóstico por imagem , Neoplasias do Colo do Útero/patologia , Adulto , Idoso , Estudos Transversais , Feminino , Humanos , Imageamento Tridimensional/economia , Imageamento por Ressonância Magnética/economia , Pessoa de Meia-Idade , Invasividade Neoplásica , Diafragma da Pelve/patologia , Estudos Prospectivos , Ultrassonografia , Neoplasias do Colo do Útero/tratamento farmacológico , Neoplasias do Colo do Útero/cirurgiaAssuntos
Desenho Assistido por Computador/instrumentação , Engenharia/instrumentação , Imageamento Tridimensional/instrumentação , Manufaturas , Pesquisa , Tecnologia/instrumentação , Desenho Assistido por Computador/economia , Desenho Assistido por Computador/tendências , Engenharia/economia , Engenharia/educação , Imageamento Tridimensional/economia , Investimentos em Saúde , Manufaturas/economia , Teste de Materiais , Polímeros/química , Impressão/economia , Impressão/instrumentação , Impressão/tendências , Pesquisa/economia , Pesquisa/tendências , Tecnologia/economia , Tecnologia/educação , Recursos HumanosRESUMO
PURPOSE: Virtual planning and guided surgery with or without prebent or milled plates are becoming more and more common for mandibular reconstruction with fibular free flaps (FFFs). Although this excellent surgical option is being used more widely, the question of the additional cost of planning and cutting-guide production has to be discussed. In capped payment systems such additional costs have to be offset by other savings if there are no special provisions for extra funding. Our study was designed to determine whether using virtual planning and guided surgery resulted in time saved during surgery and whether this time gain resulted in self-funding of such planning through the time saved. MATERIALS AND METHODS: All consecutive cases of FFF surgery were evaluated during a 2-year period. Institutional data were used to determine the price of 1 minute of operative time. The time for fibula molding, plate adaptation, and insetting was recorded. RESULTS: During the defined period, we performed 20 mandibular reconstructions using FFFs, 9 with virtual planning and guided surgery and 11 freehand cases. One minute of operative time was calculated to cost US $47.50. Multiplying this number by the time saved, we found that the additional cost of virtual planning was reduced from US $5,098 to US $1,231.50 with a prebent plate and from US $6,980 to US $3,113.50 for a milled plate. CONCLUSIONS: Even in capped health care systems, virtual planning and guided surgery including prebent or milled plates are financially viable.
Assuntos
Reconstrução Mandibular/economia , Planejamento de Assistência ao Paciente/economia , Cirurgia Assistida por Computador/economia , Interface Usuário-Computador , Idoso , Angiografia/economia , Placas Ósseas/economia , Transplante Ósseo/economia , Carcinoma de Células Escamosas/economia , Carcinoma de Células Escamosas/cirurgia , Simulação por Computador/economia , Redução de Custos , Grupos Diagnósticos Relacionados/economia , Feminino , Fíbula/cirurgia , Retalhos de Tecido Biológico/transplante , Custos de Cuidados de Saúde , Custos Hospitalares , Humanos , Imageamento Tridimensional/economia , Masculino , Neoplasias Mandibulares/economia , Neoplasias Mandibulares/cirurgia , Reconstrução Mandibular/instrumentação , Pessoa de Meia-Idade , Modelos Anatômicos , Duração da Cirurgia , Estudos Prospectivos , Suíça , Tomografia Computadorizada por Raios X/economia , Sítio Doador de Transplante/cirurgiaAssuntos
Desenho de Equipamento/métodos , Imageamento Tridimensional/métodos , Tecnologia/instrumentação , Tecnologia/métodos , Controle de Custos , Desenho de Equipamento/economia , Humanos , Imageamento Tridimensional/economia , Invenções/economia , Metais , Modelos Estruturais , Plásticos , Robótica/instrumentação , Tecnologia/economia , Cirurgia Torácica/instrumentaçãoAssuntos
Neoplasias da Mama/diagnóstico por imagem , Neoplasias da Mama/cirurgia , Mamografia/economia , Mamografia/instrumentação , Mastectomia/economia , Neoplasias da Mama/economia , Análise Custo-Benefício , Feminino , Humanos , Imageamento Tridimensional/economia , Cuidados Intraoperatórios/economia , Margens de Excisão , Mastectomia/métodos , Duração da Cirurgia , Projetos Piloto , Radiologistas , Biópsia de Linfonodo Sentinela , CirurgiõesRESUMO
The 3D acquisition of object structures has become a common technique in many fields of work, e.g., industrial quality management, cultural heritage or crime scene documentation. The requirements on the measuring devices are versatile, because spacious scenes have to be imaged with a high level of detail for selected objects. Thus, the used measuring systems are expensive and require an experienced operator. With the rise of low-cost 3D imaging systems, their integration into the digital documentation process is possible. However, common low-cost sensors have the limitation of a trade-off between range and accuracy, providing either a low resolution of single objects or a limited imaging field. Therefore, the use of multiple sensors is desirable. We show the combined use of two low-cost sensors, the Microsoft Kinect and the David laserscanning system, to achieve low-resolved scans of the whole scene and a high level of detail for selected objects, respectively. Afterwards, the high-resolved David objects are automatically assigned to their corresponding Kinect object by the use of surface feature histograms and SVM-classification. The corresponding objects are fitted using an ICP-implementation to produce a multi-resolution map. The applicability is shown for a fictional crime scene and the reconstruction of a ballistic trajectory.