Detalhe da pesquisa
1.
Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface.
J Neurochem
; 152(1): 136-150, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31264722
2.
Peptidylprolyl isomerase A governs TARDBP function and assembly in heterogeneous nuclear ribonucleoprotein complexes.
Brain
; 138(Pt 4): 974-91, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25678563
3.
A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity.
J Neurosci
; 33(6): 2408-18, 2013 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23392670
4.
The N-terminal, polybasic region of PrP(C) dictates the efficiency of prion propagation by binding to PrP(Sc).
J Neurosci
; 32(26): 8817-30, 2012 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22745483
5.
An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity.
J Biol Chem
; 286(16): 14724-36, 2011 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21385869
6.
A Drug-Based Cellular Assay (DBCA) for studying cytotoxic and cytoprotective activities of the prion protein: A practical guide.
Methods
; 53(3): 214-9, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21115124
7.
Mutant prion protein expression is associated with an alteration of the Rab GDP dissociation inhibitor alpha (GDI)/Rab11 pathway.
Mol Cell Proteomics
; 9(4): 611-22, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19996123
8.
A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein.
J Biol Chem
; 285(10): 7752-65, 2010 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19940127
9.
The hydrophobic core region governs mutant prion protein aggregation and intracellular retention.
Biochem J
; 430(3): 477-86, 2010 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20626348
10.
Pharmacological inactivation of the prion protein by targeting a folding intermediate.
Commun Biol
; 4(1): 62, 2021 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33437023
11.
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies.
Sci Adv
; 7(48): eabj1826, 2021 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34818048
12.
IL-7-induced phosphorylation of the adaptor Crk-like and other targets.
Cell Signal
; 47: 131-141, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29581031
13.
An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein.
PLoS One
; 12(8): e0182589, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28787011
14.
A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity.
ChemMedChem
; 12(16): 1286-1292, 2017 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28722340
15.
A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein.
Sci Rep
; 6: 23180, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26976106
16.
Transglutaminase 2 transamidation activity during first-phase insulin secretion: natural substrates in INS-1E.
Acta Diabetol
; 50(1): 61-72, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22382775
17.
The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells.
PLoS One
; 7(3): e33472, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22428057
18.
Characterization of detergent-insoluble proteins in ALS indicates a causal link between nitrative stress and aggregation in pathogenesis.
PLoS One
; 4(12): e8130, 2009 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-19956584
19.
Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse.
Biochem Biophys Res Commun
; 353(3): 719-25, 2007 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-17196550
20.
Regulation of redox-sensitive exofacial protein thiols in CHO cells.
Biol Chem
; 387(10-11): 1371-6, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-17081109