Detalhe da pesquisa
1.
A sensitive and scalable fluorescence anisotropy single stranded RNA targeting approach for monitoring riboswitch conformational states.
Nucleic Acids Res
; 52(6): 3164-3179, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38375901
2.
Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives.
Proc Natl Acad Sci U S A
; 117(27): 16009-16018, 2020 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32571913
3.
Docking Ligands into Flexible and Solvated Macromolecules. 8. Forming New BondsâChallenges and Opportunities.
J Chem Inf Model
; 62(4): 1061-1077, 2022 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35133156
4.
Interactions of Oral Molecular Excipients with Breast Cancer Resistance Protein, BCRP.
Mol Pharm
; 17(3): 748-756, 2020 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31990564
5.
Medicinal Chemistry Projects Requiring Imaginative Structure-Based Drug Design Methods.
Acc Chem Res
; 49(9): 1646-57, 2016 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27529781
6.
Customizable Generation of Synthetically Accessible, Local Chemical Subspaces.
J Chem Inf Model
; 57(3): 454-467, 2017 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28234470
7.
Elucidating Hyperconjugation from Electronegativity to Predict Drug Conformational Energy in a High Throughput Manner.
J Chem Inf Model
; 56(4): 788-801, 2016 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27028941
8.
Single-Point Mutation with a Rotamer Library Toolkit: Toward Protein Engineering.
J Chem Inf Model
; 55(12): 2657-71, 2015 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26623941
9.
Design, synthesis and evaluation of antiestrogen and histone deacetylase inhibitor molecular hybrids.
Bioorg Med Chem
; 23(24): 7597-606, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26613635
10.
Understanding P450-mediated Bio-transformations into Epoxide and Phenolic Metabolites.
Angew Chem Int Ed Engl
; 54(46): 13743-7, 2015 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26418278
11.
Docking ligands into flexible and solvated macromolecules. 6. Development and application to the docking of HDACs and other zinc metalloenzymes inhibitors.
J Chem Inf Model
; 54(1): 254-65, 2014 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24364808
12.
Stereo- and regioselective synthesis of polysubstituted chiral 1,4-oxazepanes.
J Org Chem
; 78(3): 872-85, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23305339
13.
Development of a computational tool to rival experts in the prediction of sites of metabolism of xenobiotics by p450s.
J Chem Inf Model
; 52(9): 2471-83, 2012 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22916680
14.
COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms.
Front Pharmacol
; 12: 633680, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33833683
15.
COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms.
Res Sq
; 2020 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32702719
16.
The activities of drug inactive ingredients on biological targets.
Science
; 369(6502): 403-413, 2020 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32703874
17.
The Recognition of Unrelated Ligands by Identical Proteins.
ACS Chem Biol
; 13(9): 2522-2533, 2018 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30095890
18.
Metabolic Instability of Cyanothiazolidine-Based Prolyl Oligopeptidase Inhibitors: a Structural Assignment Challenge and Potential Medicinal Chemistry Implications.
ChemMedChem
; 10(7): 1174-83, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26018317