Detalhe da pesquisa
1.
Arrest of mouse preterm labor until term delivery by combination therapy with atosiban and mundulone, a natural product with tocolytic efficacy.
Pharmacol Res
; 195: 106876, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37536638
2.
A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins
; 89(11): 1399-1412, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34156100
3.
Simultaneous Exposure to Intracellular and Extracellular Photosensitizers for the Treatment of Staphylococcus aureus Infections.
Antimicrob Agents Chemother
; 65(12): e0091921, 2021 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34516248
4.
Optimization of ether and aniline based inhibitors of lactate dehydrogenase.
Bioorg Med Chem Lett
; 41: 127974, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33771585
5.
Dual inhibition of Kif15 by oxindole and quinazolinedione chemical probes.
Bioorg Med Chem Lett
; 29(2): 148-154, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30528696
6.
High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling.
Anal Biochem
; 548: 44-52, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29444450
7.
Isoform selective PLD inhibition by novel, chiral 2,8-diazaspiro[4.5]decan-1-one derivatives.
Bioorg Med Chem Lett
; 28(23-24): 3670-3673, 2018 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30528979
8.
ML327 induces apoptosis and sensitizes Ewing sarcoma cells to TNF-related apoptosis-inducing ligand.
Biochem Biophys Res Commun
; 491(2): 463-468, 2017 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28716733
9.
Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange.
Proc Natl Acad Sci U S A
; 111(9): 3401-6, 2014 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550516
10.
Optimization of a small molecule probe that restores e-cadherin expression.
Bioorg Med Chem Lett
; 25(19): 4260-4, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26299347
11.
Narrow SAR in odorant sensing Orco receptor agonists.
Bioorg Med Chem Lett
; 24(12): 2613-6, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24813736
12.
Surface reengineering of RPA70N enables cocrystallization with an inhibitor of the replication protein A interaction motif of ATR interacting protein.
Biochemistry
; 52(37): 6515-24, 2013 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23962067
13.
Arrest of mouse preterm labor until term delivery by combination therapy with atosiban and mundulone, a natural product with tocolytic efficacy.
bioRxiv
; 2023 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37333338
14.
Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages.
ACS Chem Biol
; 18(8): 1891-1904, 2023 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37531659
15.
Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages.
bioRxiv
; 2023 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36747693
16.
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α.
Nat Chem Biol
; 6(11): 829-36, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20890287
17.
Further optimization of the K-Cl cotransporter KCC2 antagonist ML077: development of a highly selective and more potent in vitro probe.
Bioorg Med Chem Lett
; 22(14): 4532-5, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22727639
18.
High-Content Imaging Platform to Discover Chemical Modulators of Plasma Membrane Rafts.
ACS Cent Sci
; 8(3): 370-378, 2022 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35355811
19.
Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor.
J Med Chem
; 65(21): 14614-14629, 2022 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36300829
20.
Development of potent B-RafV600E inhibitors containing an arylsulfonamide headgroup.
Bioorg Med Chem Lett
; 21(15): 4436-40, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21733693