Identification of Polymyxin Resistance Gene mcr-10 from Different Food Samples in Shanghai, China.

This retrospective investigation (2019-2022) identified two plasmid-mediated mcr-10 from 6800 food samples in Shanghai, China and localized in a conjugative plasmid (pEC1918-mcr10) in Escherichia kobei from ready-to-eat food with high-level polymyxin B resistance, and a nonconjugative plasmid (pEC2001-mcr10) in E. coli from chicken. These genes were adjacent to ISEc36. This report highlights the emergence of mcr-10 from food samples in Shanghai, China. Active surveillance of vital resistance genes along food production chain should be performed.