1.
Bioorg Med Chem Lett
; 14(16): 4343-6, 2004 Aug 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15261299
RESUMO
SQAG9, a new class of immunosuppressive sulfoquinovosylacylglycerol, and its biotinylated derivatives have been synthesized. A T7 Phage library, composed of random cDNA fragments from Drosophila melanogaster, displayed a possible binding peptide of 14 amino acids. The immobilized synthetic peptide on a sensor chip showed a dissociation constant of K(D)=1.5 x 10(-6) against SQAG9 in a surface plasmon resonance experiment.