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Radiat Prot Dosimetry ; 200(7): 623-628, 2024 May 08.
Artigo em Inglês | MEDLINE | ID: mdl-38527175

RESUMO

Although boron neutron capture therapy (BNCT) causes minor damage to normal cells owing to the nuclear reactions induced by neutrons with major elements of tissues such as hydrogen and nitrogen, it is useful to estimate the accurate exposure dose for radiation protection. This study aims to estimate the contribution of internal exposure in radiation exposure dose for BNCT. The study was performed by referring to clinical studies at a reactor-based BNCT facility on the basis of computational dosimetry. Five irradiation regions of head and neck were selected for the estimation. The results suggest that external exposure occurred primarily in and around the irradiation field. Furthermore, during the exposure dose estimation in BNCT, internal exposure was found to be not negligible, implying that the irradiation regions in treatment planning must be considered for avoiding damage to certain critical organs that are susceptible to internal exposure.


Assuntos
Terapia por Captura de Nêutron de Boro , Terapia por Captura de Nêutron de Boro/métodos , Humanos , Dosagem Radioterapêutica , Nêutrons , Doses de Radiação , Radiometria/métodos , Proteção Radiológica/métodos , Exposição à Radiação/análise , Planejamento da Radioterapia Assistida por Computador/métodos , Método de Monte Carlo , Neoplasias de Cabeça e Pescoço/radioterapia , Imagens de Fantasmas , Simulação por Computador
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