Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros

Base de dados
Ano de publicação
Tipo de documento
Intervalo de ano de publicação
1.
Vopr Onkol ; 58(5): 688-90, 2012.
Artigo em Russo | MEDLINE | ID: mdl-23600290

RESUMO

Determined serum levels of alpha-2-macroglobulin (a2-MG) and pregnancy-associate alpha-2-glycoprotein (a2-PAG) in 98 breast cancer patients stage I-IV prior to the special antitumor treatment. Statistically significant negative correlative dependence of the a2-PAG in the blood and lifetime of patients is proved. We believe that the definition of pre-treatment level of a serum a2-MG and a2-PAG concentrations for patients with breast cancer, can be used as an additional predictor of life expectancy.


Assuntos
Biomarcadores Tumorais/sangue , Neoplasias da Mama/sangue , alfa 2-Macroglobulinas Associadas à Gravidez/metabolismo , alfa-Macroglobulinas/metabolismo , Neoplasias da Mama/patologia , Feminino , Humanos , Expectativa de Vida , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Valor Preditivo dos Testes , Prognóstico
2.
Klin Lab Diagn ; (10): 16-9, 2009 Oct.
Artigo em Russo | MEDLINE | ID: mdl-20000108

RESUMO

The authors examined serum in patients with ovarian cancer (OC; a disseminated process), ovarian cystadenoma (OCA), or external endometriosis (EM) before treatment and in apparently healthy females (a control) for the content of some acute-phase proteins and cytokines to clarify the specific features of changes in their concentrations in relation to the type of the proliferative process. It was shown that in OC, there were significant reductions in the levels of alpha2-macroglobulin (MG), plasmin (PL), alpha1-antitrypsin (AT) and statistically significantly increases in the content of lactoferrin (LF), interleukin (IL)-6, IL-8, Ig, and the regulatory transport complex of P--M. In M, the concentrations of AT were lower and those of IL-6, IL-8, and PL-MG were higher (to a lesser degree than those in OC). In OCA, the levels of MG and IgA were increased; those of IL-8 and PL-MG were decreased. The concentrations of interferon and IgM were unchanged in all groups. The findings suggest that difefrent proliferative processes initially provoke a number of changes of varying magnitude and even directions in the serum levels of inflammation reactants, which should be borne in mind when conducting clinical tests in the intraoperative and, probably, postoperative periods.


Assuntos
Proteínas de Fase Aguda/análise , Cistadenoma/sangue , Citocinas/sangue , Endometriose/sangue , Neoplasias Ovarianas/sangue , Biomarcadores/sangue , Feminino , Humanos , Doenças Ovarianas/sangue
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA