RESUMO
Background: To evaluate hyperbaric oxygen therapy (HBOT) on infection rates and repair rates during the treatment of large jaw cysts. Methods: A prospective randomized, non-blinded, controlled clinical trial included 90 patients with jaw cysts, randomly divided into three groups. Patients were treated with enucleations and bone substitute was used in the experimental and control groups. The experimental group received HBOT. The primary predictor variable was HBOT. The infection rate, repair rate, preoperative volume of the jaw cysts, age, and sex were statistically analyzed. The Fisher exact test was used to compare the infection rate and postoperative complications. The repair rate of the bone defects was analyzed using the repeated-measures analysis of variance and the least significant difference tests. The Kendall's coefficient of concordance and Kappa statistics were calculated to evaluate the consistency between the two investigators. Results: The infection rate was 3.4% in the experimental group, 14.3% in the blank group, and 32.1% in the control group (P<0.05). The repair rate in the experimental group was significantly higher than in the control and blank groups at 1, 3 and 6 months after surgery (P<0.05). Conclusion: The results showed that HBOT reduced the postoperative infection rate following the enucleation of large jaw cysts with bone substitute filling, and it also improved the bone repair rate.
Assuntos
Oxigenoterapia Hiperbárica/métodos , Cistos Maxilomandibulares/terapia , Adolescente , Adulto , Idoso , Doenças Ósseas/complicações , Doenças Ósseas/terapia , Regeneração Óssea/fisiologia , Substitutos Ósseos/uso terapêutico , China , Feminino , Humanos , Infecções/complicações , Infecções/terapia , Cistos Maxilomandibulares/patologia , Masculino , Pessoa de Meia-Idade , Procedimentos de Cirurgia Plástica , Resultado do Tratamento , Carga Tumoral , Adulto JovemRESUMO
Background: Many techniques have been proposed to close an oroantral fistula (OAF), with most of them involving transoral repairs with oral soft tissue flaps. An additional Caldwell-Luc approach or endoscopic sinus surgery (ESS) is required to address coexisting maxillary sinusitis. Objectives: This study presents the endonasal closure of an OAF through modified endoscopic medial maxillectomy (MEMM) with a free nasal mucoperichondrial-osteal graft. Materials and methods: Sixteen OAF patients who underwent closure operations in our department from May 2013 to June 2018 were retrospectively reviewed. Results: The main cause of OAF was maxillary dental cysts (56.25%). The OAF size ranged from 2 × 2 to 10 × 15 mm. The first molar (62.5%) was the most frequently involved tooth. All closures were made via MEMM, using nasal mucoperichondrial-osteal grafts harvested from the septum or nasal base. All patients were followed up for at least six months. Successful closure after a single procedure was achieved in 93.75% of cases. No obvious complications or recurrences were observed. Conclusions: Endonasal repair of OAFs via MEMM with free nasal mucosal grafts is feasible and promising. The approach preserves the normal oral and nasal physiology after surgery. It could be used alone for the closure of small to medium-sized OAFs.
Assuntos
Endoscopia/métodos , Cistos Maxilomandibulares/complicações , Fístula Bucoantral/cirurgia , Adulto , Feminino , Humanos , Cistos Maxilomandibulares/patologia , Masculino , Maxila/cirurgia , Seio Maxilar/cirurgia , Sinusite Maxilar/complicações , Pessoa de Meia-Idade , Mucosa Nasal/transplante , Septo Nasal/transplante , Fístula Bucoantral/etiologia , Estudos RetrospectivosRESUMO
The aim of the present study is to report the demographic and clinical characteristics of all jaw cysts diagnosed in a single Oral Pathology Department. 5294 cases of jaw cysts diagnosed during a 38-year period were retrospectively collected and classified according to the latest classification of Head and Neck Tumors of the World Health Organization. The patients' gender and age, as well as the main clinical features of the cysts were retrieved from biopsy report forms. Jaw cysts were more common in male patients, with a male to female ratio of 1.6:1. Most patients were in the 4th-6th decade of life, with a mean age of 42.3 ± 16.1 years. There was no jaw predilection and the majority of lesions were more commonly encountered in the anterior region of the maxilla, followed by the molar region of the mandible. The most common jaw cyst was radicular cyst followed by dentigerous cyst, residual cyst and odontogenic keratocyst. The majority of jaw cysts are of inflammatory origin and represent a sequale of pulp necrosis. However, other type of jaw cysts may also be found.
Assuntos
Cistos Maxilomandibulares/epidemiologia , Cistos Maxilomandibulares/patologia , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos RetrospectivosAssuntos
Humanos , Masculino , Pessoa de Meia-Idade , Cistos Maxilomandibulares/cirurgia , Cistos Maxilomandibulares/diagnóstico por imagem , Doenças Mandibulares/cirurgia , Doenças Mandibulares/diagnóstico por imagem , Coristoma/cirurgia , Coristoma/diagnóstico por imagem , Glândula Parótida , Imageamento por Ressonância Magnética , Radiografia Panorâmica , Cistos Maxilomandibulares/patologia , Doenças Mandibulares/patologia , Coristoma/patologiaRESUMO
Our aim was to identify the positional changes of the inferior alveolar neurovascular bundle and evaluate the relocation of the displaced mandibular canal after enucleation of a cyst. Seventy patients (72 sites) who had had cysts enucleated were divided into three groups based on the degree of encroachment of the cystic lesion into the mandibular canal and whether a bone graft had been inserted after the cyst had been enucleated. The mean (range) of patients' ages was 45 (18-75) years, and there were 29 male and 41 female patients. Group A comprised cysts with encroachment on the mandibular canal that were enucleated without a bone graft; Group B consisted of cysts with no encroachment of the mandibular canal, but were enucleated without a bone graft; and Group C comprised cysts with encroachment of the mandibular canal that were enucleated with a bone graft. The displacement of the mandibular canal was identified from analysis of computed tomographic (CT) images. Changes in the position of the mandibular canal were measured on panoramic radiographs. The mandibular canal was repositioned superiorly by a mean (SD) of 2.4 (1.65)mm after enucleation of the cyst, which was significant in Group A (p<0.001), but not in Groups B and C. These results indicate that the displaced inferior alveolar neurovascular bundles that were not surrounded by bony canal tended to relocate towards a supposedly normal position, and after enucleation of the cyst the mandibular canal was remodelled in this new location. This tendency to relocate was blocked by bone grafting. Bone grafts are therefore recommended in cases where enough bony height is required for future insertion of implants.
Assuntos
Cistos Maxilomandibulares/patologia , Mandíbula/patologia , Nervo Mandibular/patologia , Adolescente , Adulto , Idoso , Transplante Ósseo/efeitos adversos , Feminino , Humanos , Cistos Maxilomandibulares/diagnóstico por imagem , Cistos Maxilomandibulares/cirurgia , Masculino , Mandíbula/irrigação sanguínea , Mandíbula/inervação , Mandíbula/cirurgia , Pessoa de Meia-Idade , Radiografia Panorâmica , Estudos Retrospectivos , Adulto JovemAssuntos
Coristoma/diagnóstico por imagem , Coristoma/cirurgia , Cistos Maxilomandibulares/diagnóstico por imagem , Cistos Maxilomandibulares/cirurgia , Doenças Mandibulares/diagnóstico por imagem , Doenças Mandibulares/cirurgia , Glândula Parótida , Coristoma/patologia , Humanos , Cistos Maxilomandibulares/patologia , Imageamento por Ressonância Magnética , Masculino , Doenças Mandibulares/patologia , Pessoa de Meia-Idade , Radiografia PanorâmicaRESUMO
The keratocystic odontogenic tumor (KCOT) is capable of causing vast osseous destruction. Histopathological examination is pivotal for diagnosis. The diagnostic process can sometimes be hindered by tissue inflammation of KCOTs with loss of defining criteria, resulting in misdiagnosis as an odontogenic jaw cyst. We discuss the possible merits of volumetric analysis when facing this particular diagnostic dilemma and for pathophysiological characterization of KCOTs. We included 114 patients, of whom 27 were histopathologically diagnosed with a KCOT and 87 with dentigerous (n = 41) and periapical cyst (n = 46). Semiautomatic segmentation and radiological analysis of preoperative cone beam computed tomography (CBCT) image data was carried out using ITK-SNAP. The mean volumetric extent of KCOTs is significantly higher compared to non-neoplastic odontogenic jaw cysts (p = 0.001). The mean volume and standard deviation for KCOTs and non-neoplastic odontogenic jaw cysts was 10381 mm3 ± 6410 and 5813 mm3 ± 4425, respectively. Volumetric analysis reveals that KCOTs significantly exceed the mean size of non-neoplastic odontogenic jaw cysts, adding an argument in favor of the neoplastic nature of KCOTs. In the case of difficult histopathological examination, lesions with a size exceeding a value of about 3000 mm3 could be considered for close clinico-radiologic follow-up.
Assuntos
Cistos Maxilomandibulares/patologia , Tumores Odontogênicos/patologia , Adolescente , Adulto , Idoso , Criança , Tomografia Computadorizada de Feixe Cônico , Cisto Dentígero/diagnóstico , Cisto Dentígero/diagnóstico por imagem , Cisto Dentígero/patologia , Feminino , Humanos , Cistos Maxilomandibulares/diagnóstico , Cistos Maxilomandibulares/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Tumores Odontogênicos/diagnóstico , Tumores Odontogênicos/diagnóstico por imagem , Cisto Radicular/diagnóstico , Cisto Radicular/diagnóstico por imagem , Cisto Radicular/patologia , Adulto JovemRESUMO
AIMS: Conservative treatment of jaw cysts establishes low surgical complication risk and protects vital anatomical structures such as inferior alveolar nerve, maxillary sinus and permanent tooth germs. Marsupialization and decompression have been widely used in children. The aim of this study was to evaluate the results of the conservative treatment of jaw cysts in five children. MATERIALS AND METHODS: This article presents case series of marsupialization in jaw cysts associated with impacted teeth in five children. A total of nine impacted teeth within the cystic lesions were observed. RESULTS: Complete resolution of all cystic lesions and simultaneous eruption of six impacted teeth within the cyst were managed. The other two teeth were erupted orthodontically and one had to be extracted. CONCLUSIONS: Marsupialization is effective for the treatment of cystic lesions in growing patients as it preserves vital anatomical structures and enables eruption of the impacted teeth within the cyst.
Assuntos
Tomografia Computadorizada de Feixe Cônico/métodos , Cistos Maxilomandibulares/cirurgia , Procedimentos Cirúrgicos Bucais/métodos , Dente Impactado/diagnóstico por imagem , Biópsia , Criança , Feminino , Humanos , Cistos Maxilomandibulares/patologia , Masculino , Dente Impactado/cirurgia , Resultado do TratamentoRESUMO
PURPOSE: The aim of this study was to determine the age, gender, and sites of different types of odontogenic cysts (OCs) and non-OCs (nOCs) (seen in eastern Anatolian population in Turkey. MATERIALS AND METHODS: The following data were collected from the clinical records and histopathology reports of the Department of Oral and Maxillofacial Surgery and the Department of Oral Pathology, Ataturk University, Turkey, during a period of 10 years. They were analyzed descriptively in terms of incidence, age, sex, cyst type, and site. RESULTS: A total of 526 cysts were diagnosed during a 10-year period. Of these, 330 (62.7%) were in males, and 196 (37.3%) were in females, the male:female ratio was 1.7:1. There were 509 (96.8%) OCs and 17 (3.2%) nOCs. There were 406 (77.2%) inflammatory OCs and 103 (19.6%) developmental OCs. Radicular cysts were the most frequent (66.4%), followed by dentigerous (19.2%) and residual (10.8%) cysts. Only nasopalatine duct cyst was found as nOC in this study (3.2%). CONCLUSION: The distribution of jaw cysts in the Turkish Eastern Anatolian population is relatively similar to that of other populations reported in previous studies in the literature, in which most OCs were of inflammatory origin. However, the relative rates of cysts were higher than those reported in other studies.
Assuntos
Doenças Maxilomandibulares/epidemiologia , Cistos não Odontogênicos/patologia , Cistos Odontogênicos/patologia , Adolescente , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Criança , Feminino , Humanos , Incidência , Cistos Maxilomandibulares/epidemiologia , Cistos Maxilomandibulares/patologia , Masculino , Pessoa de Meia-Idade , Cistos não Odontogênicos/epidemiologia , Cistos Odontogênicos/epidemiologia , Prevalência , Cisto Radicular/epidemiologia , Estudos Retrospectivos , Distribuição por Sexo , Cirurgia Bucal , Turquia/epidemiologia , UniversidadesRESUMO
OBJECTIVE: The aim of this study was to perform an epidemiologic analysis of cases of jaw cysts treated from 1973 to 2012 at the Dentistry and Maxillofacial Surgery Unit of the Verona Hospital, Italy, and to compare the data obtained with those published in the literature. STUDY DESIGN: A retrospective survey of 2030 patients treated for jaw cysts from 1973 to 2012 was performed. The lesions were classified according to the 2005 World Health Organization histologic classification, and the following variables were analyzed: age, gender, histopathologic diagnosis, and site of onset. RESULTS: Of 2030 total lesions, there were 1970 odontogenic cysts (97.04%), 50 nonodontogenic cysts (2.46%), and 10 pseudocysts (0.49%). Of the patients, 314 were children (15.47%), and 1716 were adults (84.53%). Mean age was 37.24 years, with a male/female ratio of 1.71:1. CONCLUSIONS: There is a wide variety of cysts, some of which are subject to variations according to gender, localization, and age.
Assuntos
Cistos Maxilomandibulares/epidemiologia , Cistos Maxilomandibulares/patologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Itália/epidemiologia , Cistos Maxilomandibulares/cirurgia , Masculino , Pessoa de Meia-Idade , Estudos RetrospectivosRESUMO
Odontogenic cysts and osseous lesions are often seen as challenging diagnostic lesions but the majority of them are easily classified. This article outlines the diagnostic features required for separating the most common of odontogenic cysts and select osseous lesions of the jaws. Clinical and radiographic findings of these jaw lesions often lead to a differential diagnosis that only the histologic findings will clarify. Dentigerous cyst, keratocystic odontogenic tumor, and certain ameloblastomas that have cystic change, may have identical radiographic findings, with only separation by their specific histologic features leading to the significantly different treatments required for each. Conversely, some cystic lesions can appear histologically identical and cannot be diagnosed without the radiographic findings. Certain osseous lesions of the jaws are particularly problematic for diagnosis without the appropriate radiographic findings, and the diagnosis should probably not be attempted on the histologic findings alone. This article will integrate the necessary clinical, radiographic, and histologic findings required to address the most common odontogenic lesions.
Assuntos
Cistos Maxilomandibulares/diagnóstico , Neoplasias Maxilomandibulares/diagnóstico , Tumores Odontogênicos/diagnóstico , Diagnóstico Diferencial , Humanos , Cistos Maxilomandibulares/diagnóstico por imagem , Cistos Maxilomandibulares/patologia , Neoplasias Maxilomandibulares/diagnóstico por imagem , Neoplasias Maxilomandibulares/patologia , Tumores Odontogênicos/diagnóstico por imagem , Tumores Odontogênicos/patologiaRESUMO
Cherubism is a rare disorder with autosomal dominant inheritance. It is classified as a benign fibro-osseous lesions and may involve either facial bone. Its typical dentofacial deformities are caused by mutations in the SH3BP2 gene. The protein encoded by SH3BP2 had a significant role in the regulation of osteoblasts and osteoclasts. Accordingly with the radiological findings, differential diagnoses includes fibrous dysplasia, giant cell granuloma, osteosarcoma, juvenile ossifying fibroma, fibrous osteoma, odontogenic cyst and hyperparathyroidism. The aim of the present report is twofold. First, we examine the importance of the proper management of these cases. Second, we describe this rare syndrome with the goal of proposing suitable treatments.
Assuntos
Querubismo , Proteínas Adaptadoras de Transdução de Sinal/genética , Querubismo/diagnóstico , Querubismo/genética , Querubismo/terapia , Criança , Tratamento Conservador , Diagnóstico Diferencial , Gerenciamento Clínico , Genes Dominantes , Humanos , Cistos Maxilomandibulares/diagnóstico por imagem , Cistos Maxilomandibulares/genética , Cistos Maxilomandibulares/patologia , Masculino , Osteoblastos/patologia , Osteoclastos/patologiaRESUMO
OBJECTIVE: Lucent lesions of the pediatric mandible may present variably. Cysts, neoplasms, and developmental and inflammatory conditions have a host of possible causes. There is also substantial overlap in the imaging appearance of cysts and that of benign but locally aggressive tumors that need to undergo resection. CONCLUSION: The purpose of this article is to present common and uncommon lucent lesions of the mandible in children, with an emphasis on benign abnormalities. Discussions of imaging and histopathologic features are provided.
Assuntos
Cistos Maxilomandibulares/diagnóstico por imagem , Neoplasias Mandibulares/diagnóstico por imagem , Maxila/diagnóstico por imagem , Osteíte/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos , Criança , Pré-Escolar , Diagnóstico Diferencial , Feminino , Humanos , Lactente , Recém-Nascido , Cistos Maxilomandibulares/patologia , Masculino , Neoplasias Mandibulares/patologia , Maxila/patologia , Osteíte/patologiaRESUMO
Cistos odontogênicos são aqueles derivados de remanescentes epiteliais associados com a formação dos dentes. Representam um desenvolvimento anormal da odontogênese, em algum momento, podendo derivar da lâmina dentária, bainha de Hertwig ou do órgão do esmalte. Na medida em que aumenta a pressão osmótica, o centro afasta-se da periferia e o cisto aumenta de tamanho. Com raras exceções, no osso, cistos limitados por epitélio são observados somente nos maxilares. O tratamento de escolha é o cirúrgico, com exodontia do dente envolvido e curetagem da lesão cística. No entanto, quando se trata de um paciente jovem, e o dente envolvido não é o terceiro molar, deve-se tentar a marsupialização e o posterior acompanhamento da erupção do dente, a fim de preservá-lo e mantê-lo no arco dentário. O presente trabalho tem o objetivo de apresentar um caso clínico de um paciente de 13 anos de idade, o qual apresentava o elemento 47 incluso e envolvido em um cisto odontogênico. O tratamento de escolha foi o conservador, através da marsupialização. Após 2 anos de acompanhamento, o dente erupcionou e entrou em função normalmente, mostrando que o tratamento proposto foi bem-sucedido (AU).
Odontogenic cysts are those derived from epithelial remnants associated to the formation of the teeth. They represent an abnormal development of odontogenesis, and at some point may derive from the dental lamina, Hertwig sheath or the enamel organ. As the osmotic pressure increases, the center moves away from the periphery and increases the cyst in size. With rare exceptions, the bone, epithelium for limited cysts are observed only in the jaw. The treatment of choice is surgery, with extraction of the tooth involved and curettage of the cystic lesion. However, when it comes to a young patient, and the tooth involved is not the third molar, one should try the marsupialization and subsequent monitoring of tooth eruption, in order to preserve it and keep it in the dental arch. This paper aims to present a case of a 13-year-old patient, who had the element 47 included and involved in an odontogenic cyst. The treatment was conservative by marsupialization. After 2 years of follow up, the tooth erupted and came into function normally, showing that the treatment was successful (AU).
Assuntos
Humanos , Masculino , Adolescente , Relatos de Casos , Tratamento Conservador/métodos , Cistos Maxilomandibulares/patologia , Cistos Odontogênicos/patologia , Procedimentos Cirúrgicos Operatórios/métodos , Brasil , Radiografia Panorâmica/instrumentaçãoRESUMO
OBJECTIVE: This study described the clinical, surgical, and radiographic findings of simple bone cysts. METHODS: A retrospective study was conducted for patients diagnosed with simple bone cysts in the Department of Oral and Maxillofacial Surgery of the Affiliated Stomatological Hospital of Nanchang University from March 2005 to March 2015. Clinical, radio-graphic, surgical, and follow-up data were gathered. Results were statistically analyzed by central tendency and dispersionusing SPSS 20.0 software. RESULTS: Eleven cases of simple bone cysts were collected, including three male and eight female patients. Ten cases (90.9%) were asymptomatic and one case developed symptoms of swelling. All of the cases had no history of trauma in the affected area, and all were solitary; ten cases (90.9%) were unilocular, and one (9.1%) was multilocular.The shape of each lesion could be assigned to four categories: cone (3 cases), round (2 cases), oval (4 cases), and irregular (2 cases). The treatment in 10 cases consisted of surgery to explore the cavity and curettage of the bone walls. During surgery,the bone cavity in seven cases (70%) was vacant, whereas serous fluid was found in two cases (20%) and serous-bloody fluid in one case (10%). Of the ten cases, three cases exhibited complete bone healing and seven cases showed new bone formation. CONCLUSION: Simple bone cysts of the jaws are usually asymptomatic and appear incidentally on routine radiographies. The prevalence is higher in the mandible and young people. The patient usually has no history of trauma, and the bone cavity of lesion is mostly vacant. Curettage of the bone walls of the lesion is suggested for simple bone cysts. Systemic clinical and radiologic follow-up are necessary to ensure successful treatment.
Assuntos
Cistos Maxilomandibulares/diagnóstico , Doenças Mandibulares , Cistos Ósseos , Cárie Dentária , Feminino , Hospitais , Humanos , Cistos Maxilomandibulares/patologia , Masculino , Mandíbula , Radiologia , Estudos Retrospectivos , SoftwareRESUMO
PURPOSE: Differentiating between ganglion and synovial cysts by standard histology is difficult, leading to inaccurate statements on frequency for each of these periarticular lesions. The purpose of this study was to use immunohistochemical (IHC) analysis to 1) calculate the accuracy of the histologic diagnoses, 2) determine the frequency of ganglion and synovial cysts of the temporomandibular joint (TMJ), and 3) compare the frequency of these lesions in the TMJ compared with the extracranial skeleton in patients treated at Massachusetts General Hospital (MGH). MATERIALS AND METHODS: This is a retrospective cohort study of all patients undergoing treatment of TMJ cysts at MGH from 2001 through 2013. IHC analysis of tissue samples for each patient was completed and compared with the original histologic diagnoses. Categorical variables, including age, gender, and sidedness, were recorded. A natural language search of the MGH Department of Pathology database determined the frequency of extracranial periarticular cysts during the same period. RESULTS: Thirteen patients met the inclusion criteria. Eleven cysts were synovial and 2 were ganglion based on histology. IHC analysis identified 2 false-positive synovial cyst diagnoses, resulting in 100% sensitivity and 50% specificity for the original histologic assessment and a percentage error of 22%. Of the periarticular TMJ lesions, 69% were synovial cysts and 31% were ganglion cysts. The frequency of TMJ versus extracranial ganglion cysts was 0.24%, and the frequency of TMJ versus extracranial synovial cysts was 0.60% based on 3,176 extracranial cysts (1,506 synovial; 1,670 ganglion). CONCLUSION: This study represents the largest single-institution experience with periarticular cysts of the TMJ, and contrary to previous reports, TMJ cysts appear to be more frequently synovial than ganglion. IHC can be used to overcome the relatively poor specificity of histologic diagnosis of synovial cysts.
Assuntos
Cistos Glanglionares/diagnóstico , Cistos Maxilomandibulares/diagnóstico , Cisto Sinovial/diagnóstico , Transtornos da Articulação Temporomandibular/diagnóstico , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Diagnóstico Diferencial , Cistos Glanglionares/patologia , Humanos , Imuno-Histoquímica , Cistos Maxilomandibulares/patologia , Imageamento por Ressonância Magnética , Pessoa de Meia-Idade , Estudos Retrospectivos , Sensibilidade e Especificidade , Cisto Sinovial/patologia , Transtornos da Articulação Temporomandibular/patologiaRESUMO
OBJECTIVE: To determine the incidence, age, gender, jaw-sites and subtypes of radicular cyst, and to determine the incidence of ameloblastomatous change in radicular cyst in a Nigerian population. METHOD: A 10-year retrospective analysis of all diagnosed orofacial lesions in the Department of Oral Pathology and Medicine, University of Benin Teaching Hospital, Benin City, Nigeria. RESULTS: From the 785 diagnosed orofacial lesions within the study period; there were 54 (6.9%) cases of radicular cysts of the jaws. The peak age group was the 3(rd) decade (n=23, 42.6%) with a mean age of 31 ± 1.7 years. There were 29 (53.7%) males and 25 (46.3%) females, giving a ratio of 1.2:1. The mandible was the commonest jaw-site (n=32, 59.3%). There were 12 (22.2%) cases of periapical cyst which were significantly associated with anterior maxillary site (n=8, 14.8%) [p=0.001]. Seven (13.0%) cases of cystic ameloblastoma were diagnosed among the radicular cysts, with a predilection of the lesions for 3(rd) and 4(th) decades of life (n=6, 11.1%), and posterior mandible (n=5, 9.3%). CONCLUSION: This study showed a low incidence of radicular cyst of the jaw among orofacial lesions and a relatively higher incidence of ameloblastomatous change in radicular cyst compared to previous reports. Immuno-histochemical examination is recommended to differentiate radicular cyst with ameloblastomatous-like change from cystic ameloblastoma arising from radicular cyst.
Assuntos
Ameloblastoma/patologia , Cistos Maxilomandibulares/patologia , Cisto Radicular/patologia , Adolescente , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Cistos Maxilomandibulares/epidemiologia , Masculino , Pessoa de Meia-Idade , Nigéria/epidemiologia , Cisto Radicular/epidemiologia , Estudos Retrospectivos , Distribuição por Sexo , Adulto JovemRESUMO
OBJECTIVE: The goal of this study was to reveal clinical and pathologic findings on idiopathic bone cavity lesions (IBC). STUDY DESIGN: A retrospective analysis of 20 IBC cases diagnosed from 2004 to 2014 from a university-based maxillofacial pathology service was performed and included all pertinent clinical, histologic, and radiographic findings. RESULTS: Eleven women (age = 36 ± 12.7) and 9 men (age = 23 ± 17.9) diagnosed with IBC were selected for analysis. There was a higher African-American female predilection (40%). Thirty percent of the cases were associated with florid cementoosseous dysplasia (COD) (all middle-aged African-American women). The location of the lesions was mandibular in 85% of the patients. All symptomatic patients (25%) had concomitant COD. Only 1 patient reported previous trauma, and only 1 patient had prior orthodontic treatment. Follow-up period ranged from 1 to 8 years, with only 1 recurrence 3 years after surgery. CONCLUSIONS: The results suggest that IBC concurrent with COD may not be as rare as the literature implies. Clinicians must be attentive to this possible relationship to ensure accurate diagnosis and appropriate treatment.