1.
Bioorg Med Chem Lett
; 17(21): 5983-8, 2007 Nov 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-17827000
RESUMEN
Synthesis, pharmacology, and pharmacokinetic profiles of (1R, 2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile are reported. This compound demonstrated remarkable potency for stimulating hair growth in a male C3H mouse model as well as reducing sebum production in the male Syrian hamster ear model.