Detalhe da pesquisa
1.
Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas.
Mol Cell
; 74(5): 936-950.e5, 2019 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30975459
2.
Kidney Organoids Generated Using an Allelic Series of NPHS2 Point Variants Reveal Distinct Intracellular Podocin Mistrafficking.
J Am Soc Nephrol
; 34(1): 88-109, 2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36167728
3.
Generating Kidney from Stem Cells.
Annu Rev Physiol
; 81: 335-357, 2019 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30742789
4.
Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines.
Development
; 146(1)2019 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30567931
5.
Evaluation of variability in human kidney organoids.
Nat Methods
; 16(1): 79-87, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30573816
6.
Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation.
Nat Mater
; 20(2): 260-271, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33230326
7.
Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms.
Am J Hum Genet
; 102(5): 816-831, 2018 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29706353
8.
Reporter-based fate mapping in human kidney organoids confirms nephron lineage relationships and reveals synchronous nephron formation.
EMBO Rep
; 20(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30858339
9.
A Toolbox to Characterize Human Induced Pluripotent Stem Cell-Derived Kidney Cell Types and Organoids.
J Am Soc Nephrol
; 30(10): 1811-1823, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31492807
10.
Direct reprogramming to human nephron progenitor-like cells using inducible piggyBac transposon expression of SNAI2-EYA1-SIX1.
Kidney Int
; 95(5): 1153-1166, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30827514
11.
Functional Assessment of Patient-Derived Retinal Pigment Epithelial Cells Edited by CRISPR/Cas9.
Int J Mol Sci
; 19(12)2018 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30572641
12.
ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy.
Eur Heart J
; 37(33): 2586-90, 2016 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27106955
13.
Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation.
Hum Mol Genet
; 23(23): 6332-44, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25008112
14.
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis.
Proc Natl Acad Sci U S A
; 110(39): 15644-9, 2013 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23940360
15.
Phosphorylation regulates human OCT4.
Proc Natl Acad Sci U S A
; 109(19): 7162-8, 2012 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22474382
16.
Chemically defined conditions for human iPSC derivation and culture.
Nat Methods
; 8(5): 424-9, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21478862
17.
Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy.
Proc Natl Acad Sci U S A
; 108(16): 6537-42, 2011 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21464322
18.
Generation of heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2/COUP-TFII knockout human iPSC lines.
Stem Cell Res
; 76: 103374, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38458031
19.
Generation of a human ACTA1-tdTomato reporter iPSC line using CRISPR/Cas9 editing.
Stem Cell Res
; 75: 103313, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38277710
20.
Generation of iPSC lines from peripheral blood mononuclear cells from five healthy donors.
Stem Cell Res
; 69: 103109, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37150143