Detalhe da pesquisa
1.
The prostaglandin E2 EP3 receptor has disparate effects on islet insulin secretion and content in ß-cells in a high-fat diet-induced mouse model of obesity.
Am J Physiol Endocrinol Metab
; 326(5): E567-E576, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38477664
2.
Metformin Monotherapy Alters the Human Plasma Lipidome Independent of Clinical Markers of Glycemic Control and Cardiovascular Disease Risk in a Type 2 Diabetes Clinical Cohort.
J Pharmacol Exp Ther
; 386(2): 169-180, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36918276
3.
Agonist-independent Gαz activity negatively regulates beta-cell compensation in a diet-induced obesity model of type 2 diabetes.
J Biol Chem
; 296: 100056, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33172888
4.
Ultrahigh-Resolution Mass Spectrometry-Based Platform for Plasma Metabolomics Applied to Type 2 Diabetes Research.
J Proteome Res
; 20(1): 463-473, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33054244
5.
The influence of intermittent hypoxia, obesity, and diabetes on male genitourinary anatomy and voiding physiology.
Am J Physiol Renal Physiol
; 321(1): F82-F92, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34121451
6.
Prostaglandin EP3 receptor signaling is required to prevent insulin hypersecretion and metabolic dysfunction in a non-obese mouse model of insulin resistance.
Am J Physiol Endocrinol Metab
; 321(4): E479-E489, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34229444
7.
Complement 1q-like-3 protein inhibits insulin secretion from pancreatic ß-cells via the cell adhesion G protein-coupled receptor BAI3.
J Biol Chem
; 293(47): 18086-18098, 2018 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30228187
8.
Short-term methionine deprivation improves metabolic health via sexually dimorphic, mTORC1-independent mechanisms.
FASEB J
; 32(6): 3471-3482, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29401631
9.
Restoration of metabolic health by decreased consumption of branched-chain amino acids.
J Physiol
; 596(4): 623-645, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29266268
10.
The gastrin-releasing peptide analog bombesin preserves exocrine and endocrine pancreas morphology and function during parenteral nutrition.
Am J Physiol Gastrointest Liver Physiol
; 309(6): G431-42, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26185331
11.
Gαz-independent and -dependent Improvements With EPA Supplementation on the Early Type 1 Diabetes Phenotype of NOD Mice.
J Endocr Soc
; 8(7): bvae100, 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38831864
12.
Deletion of GαZ protein protects against diet-induced glucose intolerance via expansion of ß-cell mass.
J Biol Chem
; 287(24): 20344-55, 2012 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22457354
13.
Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 ß-cell line.
Am J Physiol Endocrinol Metab
; 305(5): E600-10, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23860123
14.
EP3 signaling is decoupled from the regulation of glucose-stimulated insulin secretion in ß-cells compensating for obesity and insulin resistance.
Islets
; 15(1): 2223327, 2023 Dec 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37415404
15.
What the BTBR/J mouse has taught us about diabetes and diabetic complications.
iScience
; 26(7): 107036, 2023 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37360692
16.
Effects of Arachidonic Acid and Its Metabolites on Functional Beta-Cell Mass.
Metabolites
; 12(4)2022 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35448529
17.
A human pancreatic ECM hydrogel optimized for 3-D modeling of the islet microenvironment.
Sci Rep
; 12(1): 7188, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35504932
18.
Plasma Prostaglandin E2 Metabolite Levels Predict Type 2 Diabetes Status and One-Year Therapeutic Response Independent of Clinical Markers of Inflammation.
Metabolites
; 12(12)2022 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36557272
19.
Rap1 promotes multiple pancreatic islet cell functions and signals through mammalian target of rapamycin complex 1 to enhance proliferation.
J Biol Chem
; 285(21): 15777-85, 2010 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20339002
20.
Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS-1 (832/3) cell glucose-stimulated insulin secretion.
Pharmacol Res Perspect
; 9(2): e00736, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33694300