Detalhe da pesquisa
1.
Application of population physiologically based pharmacokinetic modelling to optimize target expression and clearance mechanisms of therapeutic monoclonal antibodies.
Br J Clin Pharmacol
; 89(9): 2691-2702, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37055941
2.
Quantitative assessment of the exposure-efficacy relationship of glucocerebrosidase using Markovian elements in Gaucher patients treated with enzyme replacement therapy.
Br J Clin Pharmacol
; 88(6): 2727-2737, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34957594
3.
Evaluation of ABC gene polymorphisms on the pharmacokinetics and pharmacodynamics of capecitabine in colorectal patients: Implications for dosing recommendations.
Br J Clin Pharmacol
; 87(3): 905-915, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32559325
4.
In vitro skin penetration of bronidox, bronopol and formaldehyde from cosmetics.
Regul Toxicol Pharmacol
; 122: 104888, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33577887
5.
A preclinical study to model taurine pharmokinetics in the undernourished rat.
Br J Nutr
; 119(7): 826-835, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29569537
6.
Usefulness of Caco-2/HT29-MTX and Caco-2/HT29-MTX/Raji B Coculture Models To Predict Intestinal and Colonic Permeability Compared to Caco-2 Monoculture.
Mol Pharm
; 14(4): 1264-1270, 2017 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28263609
7.
Impact of Undernutrition on the Pharmacokinetics and Pharmacodynamics of Anticancer Drugs: A Literature Review.
Nutr Cancer
; 69(4): 555-563, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28353359
8.
Closed-Loop Doluisio (Colon, Small Intestine) and Single-Pass Intestinal Perfusion (Colon, Jejunum) in Rat-Biophysical Model and Predictions Based on Caco-2.
Pharm Res
; 35(1): 2, 2017 12 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29288412
9.
Levofloxacin effect on erlotinib absorption. Evaluation of the interaction in undernutrition situations through population pharmacokinetic analysis in rats.
Biopharm Drug Dispos
; 38(5): 315-325, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28099756
10.
Multi-output model with Box-Jenkins operators of linear indices to predict multi-target inhibitors of ubiquitin-proteasome pathway.
Mol Divers
; 19(2): 347-56, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25754075
11.
Study of the Influence of Bone Cement Type and Mixing Method on the Bioactivity and the Elution Kinetics of Ciprofloxacin.
J Arthroplasty
; 30(7): 1243-9, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25743107
12.
In vitro-in vivo correlations: general concepts, methodologies and regulatory applications.
Drug Dev Ind Pharm
; 41(12): 1935-47, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26133085
13.
Chitosan-xanthan gum microparticle-based oral tablet for colon-targeted and sustained delivery of quercetin.
J Microencapsul
; 31(7): 694-9, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24903450
14.
Bioequivalence risk assessment of oral formulations containing racemic ibuprofen through a chiral physiologically based pharmacokinetic model of ibuprofen enantiomers.
Eur J Pharm Biopharm
; 199: 114293, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38641229
15.
Enzyme-responsive silica mesoporous supports capped with azopyridinium salts for controlled delivery applications.
Chemistry
; 19(4): 1346-56, 2013 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23225567
16.
Improving oral bioavailability and pharmacokinetics of liposomal metformin by glycerolphosphate-chitosan microcomplexation.
AAPS PharmSciTech
; 14(2): 485-96, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23471836
17.
Pharmacometric characterization of entero-hepatic circulation processes of orally administered formulations of amiodarone under complex binding kinetics.
Eur J Pharm Sci
; 174: 106198, 2022 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35504449
18.
A physiologically based pharmacokinetic model for open acid and lactone forms of atorvastatin and metabolites to assess the drug-gene interaction with SLCO1B1 polymorphisms.
Biomed Pharmacother
; 156: 113914, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36306592
19.
Impact of Pharmacokinetic and Pharmacodynamic Properties of Monoclonal Antibodies in the Management of Psoriasis.
Pharmaceutics
; 14(3)2022 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35336028
20.
Population Pharmacokinetic/Pharmacodynamic Modelling of Daptomycin for Schedule Optimization in Patients with Renal Impairment.
Pharmaceutics
; 14(10)2022 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36297661