Detalhe da pesquisa
1.
Early-onset brain alterations during postnatal development in a mouse model of CDKL5 deficiency disorder.
Neurobiol Dis
; 182: 106146, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37164289
2.
Cardiac Functional and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder.
Int J Mol Sci
; 24(6)2023 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982627
3.
Luteolin Treatment Ameliorates Brain Development and Behavioral Performance in a Mouse Model of CDKL5 Deficiency Disorder.
Int J Mol Sci
; 23(15)2022 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35955854
4.
A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder.
Neurobiol Dis
; 153: 105304, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33621640
5.
Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder.
J Neuroinflammation
; 18(1): 155, 2021 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34238328
6.
Treatment with a GSK-3ß/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder.
Int J Mol Sci
; 22(11)2021 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34073043
7.
CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder.
Hum Mol Genet
; 27(9): 1572-1592, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29474534
8.
Expression of Concern: CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains.
J Cell Sci
; 135(18)2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36155802
9.
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder.
Hum Mol Genet
; 25(18): 3887-3907, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27466189
10.
Treatment with the GSK3-beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice.
Eur J Neurosci
; 47(9): 1054-1066, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29603837
11.
Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder.
Neural Plast
; 2018: 9726950, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29977282
12.
Correction: Lot1 is a key element of the pituitary adenylate cyclase-activating polypeptide (PACAP)/cyclic AMP pathway that negatively regulates neuronal precursor proliferation.
J Biol Chem
; 295(11): 3746, 2020 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32169856
13.
Correction: CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3ß/ß-catenin signaling.
J Biol Chem
; 295(10): 3388, 2020 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32144151
14.
Withdrawal: The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for Down syndrome.
J Biol Chem
; 295(10): 3392, 2020 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32144155
15.
Corrigendum to "APP-dependent alteration of GSK3ß activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome" [Neurobiology of Disease 67 (2014) 24-36].
Neurobiol Dis
; 138: 104769, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-31992468
16.
Inhibition of GSK3ß rescues hippocampal development and learning in a mouse model of CDKL5 disorder.
Neurobiol Dis
; 82: 298-310, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26143616
17.
Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome.
Neurobiol Dis
; 82: 385-396, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26254735
18.
The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for Down syndrome.
J Biol Chem
; 288(29): 20817-20829, 2013 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23740250
19.
APP-dependent alteration of GSK3ß activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome.
Neurobiol Dis
; 67: 24-36, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24636797
20.
Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3ß signaling.
Neurobiol Dis
; 70: 53-68, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24952363