Detalhe da pesquisa
1.
Rosiglitazone via PPARγ-dependent suppression of oxidative stress attenuates endothelial dysfunction in rats fed homocysteine thiolactone.
J Cell Mol Med
; 19(4): 826-35, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25656735
2.
Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer.
bioRxiv
; 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38260423
3.
LGR4 and LGR5 form distinct homodimers that only LGR4 complexes with RNF43/ZNRF3 to provide high affinity binding of R-spondin ligands.
Sci Rep
; 13(1): 10796, 2023 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37402772
4.
Drug Conjugates of Antagonistic R-Spondin 4 Mutant for Simultaneous Targeting of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors 4/5/6 for Cancer Treatment.
J Med Chem
; 64(17): 12572-12581, 2021 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34406767
5.
Effect of glycyrrhizin on the activity of CYP3A enzyme in humans.
Eur J Clin Pharmacol
; 66(8): 805-810, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20393696
6.
Unlike LGR4, LGR5 potentiates Wnt-ß-catenin signaling without sequestering E3 ligases.
Sci Signal
; 13(660)2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33262293
7.
Simultaneous action of the flavonoid quercetin on cytochrome P450 (CYP) 1A2, CYP2A6, N-acetyltransferase and xanthine oxidase activity in healthy volunteers.
Clin Exp Pharmacol Physiol
; 36(8): 828-33, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19215233
8.
The most common RNF43 mutant G659Vfs*41 is fully functional in inhibiting Wnt signaling and unlikely to play a role in tumorigenesis.
Sci Rep
; 9(1): 18557, 2019 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31811196
9.
Hepatic nuclear factor 1alpha inhibitor ursodeoxycholic acid influences pharmacokinetics of the organic anion transporting polypeptide 1B1 substrate rosuvastatin and bilirubin.
Drug Metab Dispos
; 36(8): 1453-6, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18443034
10.
Rifampicin alters atorvastatin plasma concentration on the basis of SLCO1B1 521T>C polymorphism.
Clin Chim Acta
; 405(1-2): 49-52, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19374892
11.
Effects of genetic polymorphisms of CYP3A4, CYP3A5 and MDR1 on cyclosporine pharmacokinetics after renal transplantation.
Clin Exp Pharmacol Physiol
; 33(11): 1093-8, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17042920
12.
[Protective effect of Na(+)-H+ exchanger inhibitor cariporide on the injury of vascular endothelial function induced by hypercholesterolemia].
Hunan Yi Ke Da Xue Xue Bao
; 27(1): 13-6, 2002 Feb 28.
Artigo
em Zh
| MEDLINE | ID: mdl-12575221