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1.

N-glycan-mediated shielding of ADAMTS13 prevents binding of pathogenic autoantibodies in immune-mediated TTP.

Ercig, Bogac; Graça, Nuno A G; Kangro, Kadri; Arfman, Tom; Wichapong, Kanin; Hrdinová, Johana; Kaijen, Paul; van Alphen, Floris P J; van den Biggelaar, Maartje; Vanhoorelbeke, Karen; Veyradier, Agnès; Coppo, Paul; Reutelingsperger, Chris; Nicolaes, Gerry A F; Männik, Andres; Voorberg, Jan.

Blood ; 137(19): 2694-2698, 2021 05 13.

Artículo en Inglés | MEDLINE | ID: mdl-33544829

2.

Phagocytosis of platelets opsonized with differently glycosylated anti-HLA hIgG1 by monocyte-derived macrophages.

van Osch, Thijs L J; Steuten, Juulke; Nouta, Jan; Koeleman, Carolien A M; Bentlage, Arthur E H; Heidt, Sebastiaan; Mulder, Arend; Voorberg, Jan; van Ham, S Marieke; Wuhrer, Manfred; Ten Brinke, Anja; Vidarsson, Gestur.

Platelets ; 34(1): 2129604, 2023 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-36185007

3.

Epigenetic Modification of the von Willebrand Factor Promoter Drives Platelet Aggregation on the Pulmonary Endothelium in Chronic Thromboembolic Pulmonary Hypertension.

Manz, Xue D; Szulcek, Robert; Pan, Xiaoke; Symersky, Petr; Dickhoff, Chris; Majolée, Jisca; Kremer, Veerle; Michielon, Elisabetta; Jordanova, Ekaterina S; Radonic, Teodora; Bijnsdorp, Irene V; Piersma, Sander R; Pham, Thang V; Jimenez, Connie R; Vonk Noordegraaf, Anton; de Man, Frances S; Boon, Reinier A; Voorberg, Jan; Hordijk, Peter L; Aman, Jurjan; Bogaard, Harm Jan.

Am J Respir Crit Care Med ; 205(7): 806-818, 2022 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-35081007

4.

Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity.

Ercig, Bogac; Arfman, Tom; Hrdinova, Johana; Wichapong, Kanin; Reutelingsperger, Chris P M; Vanhoorelbeke, Karen; Nicolaes, Gerry A F; Voorberg, Jan.

J Biol Chem ; 297(4): 101132, 2021 10.

Artículo en Inglés | MEDLINE | ID: mdl-34461090

5.

TTP: From empiricism for an enigmatic disease to targeted molecular therapies.

Graça, Nuno A G; Joly, Bérangère S; Voorberg, Jan; Vanhoorelbeke, Karen; Béranger, Nicolas; Veyradier, Agnès; Coppo, Paul.

Br J Haematol ; 197(2): 156-170, 2022 04.

Artículo en Inglés | MEDLINE | ID: mdl-35146746

6.

Platelet degranulation and bleeding phenotype in a large cohort of Von Willebrand disease patients.

Swinkels, Maurice; Atiq, Ferdows; Bürgisser, Petra E; van Moort, Iris; Meijer, Karina; Eikenboom, Jeroen; Fijnvandraat, Karin; van Galen, Karin P M; de Meris, Joke; Schols, Saskia E M; van der Bom, Johanna G; Cnossen, Marjon H; Voorberg, Jan; Leebeek, Frank W G; Bierings, Ruben; Jansen, A J Gerard.

Br J Haematol ; 197(4): 497-501, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-36165954

7.

Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura.

Roose, Elien; Schelpe, An-Sofie; Tellier, Edwige; Sinkovits, György; Joly, Bérangère S; Dekimpe, Charlotte; Kaplanski, Gilles; Le Besnerais, Maelle; Mancini, Ilaria; Falter, Tanja; Von Auer, Charis; Feys, Hendrik B; Reti, Marienn; Rossmann, Heidi; Vandenbulcke, Aline; Pareyn, Inge; Voorberg, Jan; Greinacher, Andreas; Benhamou, Ygal; Deckmyn, Hans; Fijnheer, Rob; Prohászka, Zoltan; Peyvandi, Flora; Lämmle, Bernhard; Coppo, Paul; De Meyer, Simon F; Veyradier, Agnès; Vanhoorelbeke, Karen.

Blood ; 136(3): 353-361, 2020 07 16.

Artículo en Inglés | MEDLINE | ID: mdl-32356859

8.

Syntaxin 5 determines Weibel-Palade body size and von Willebrand factor secretion by controlling Golgi architecture.

Kat, Marije; Karampini, Ellie; Hoogendijk, Arie J; Bürgisser, Petra E; Mulder, Aat A; Van Alphen, Floris P J; Olins, Jenny; Geerts, Dirk; Van den Biggelaar, Maartje; Margadant, Coert; Voorberg, Jan; Bierings, Ruben.

Haematologica ; 107(8): 1827-1839, 2022 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-35081689

9.

Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets.

Van Osch, Thijs L J; Oosterhoff, Janita J; Bentlage, Arthur E H; Nouta, Jan; Koeleman, Carolien A M; Geerdes, Dionne M; Mok, Juk Yee; Heidt, Sebastiaan; Mulder, Arend; Van Esch, Wim J E; Kapur, Rick; Porcelijn, Leendert; Van der Schoot, C Ellen; De Haas, Masja; Wuhrer, Manfred; Voorberg, Jan; Vidarsson, Gestur.

Haematologica ; 107(10): 2432-2444, 2022 10 01.

Artículo en Inglés | MEDLINE | ID: mdl-35354253

10.

Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear.

Hrdinova, Johana; Fernández, Delia I; Ercig, Bogac; Tullemans, Bibian M E; Suylen, Dennis P L; Agten, Stijn M; Jurk, Kerstin; Hackeng, Tilman M; Vanhoorelbeke, Karen; Voorberg, Jan; Reutelingsperger, Chris P M; Wichapong, Kanin; Heemskerk, Johan W M; Nicolaes, Gerry A F.

Int J Mol Sci ; 23(4)2022 Feb 12.

Artículo en Inglés | MEDLINE | ID: mdl-35216161

11.

Sec22b determines Weibel-Palade body length by controlling anterograde ER-Golgi transport.

Karampini, Ellie; Bürgisser, Petra E; Olins, Jenny; Mulder, Aat A; Jost, Carolina R; Geerts, Dirk; Voorberg, Jan; Bierings, Ruben.

Haematologica ; 106(4): 1138-1147, 2021 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-32336681

12.

Orchestration of Primary Hemostasis by Platelet and Endothelial Lysosome-Related Organelles.

Karampini, Ellie; Bierings, Ruben; Voorberg, Jan.

Arterioscler Thromb Vasc Biol ; 40(6): 1441-1453, 2020 06.

Artículo en Inglés | MEDLINE | ID: mdl-32375545

13.

CSI: Weibel-Palade bodies.

Bierings, Ruben; Voorberg, Jan.

Blood ; 141(8): 820-821, 2023 02 23.

Artículo en Inglés | MEDLINE | ID: mdl-36821184

14.

Modifying ADAMTS13 to modulate binding of pathogenic autoantibodies of patients with acquired thrombotic thrombocytopenic purpura.

Graça, Nuno A G; Ercig, Bogac; Carolina Velásquez Pereira, Leydi; Kangro, Kadri; Kaijen, Paul; Nicolaes, Gerry A F; Veyradier, Agnès; Coppo, Paul; Vanhoorelbeke, Karen; Männik, Andres; Voorberg, Jan.

Haematologica ; 105(11): 2619-2630, 2020 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-33131251

15.

Prevention of the anti-factor VIII memory B-cell response by inhibition of Bruton tyrosine kinase in experimental hemophilia A.

Delignat, Sandrine; Russick, Jules; Gangadharan, Bagirath; Rayes, Julie; Ing, Mathieu; Voorberg, Jan; Kaveri, Srinivas V; Lacroix-Desmazes, Sébastien.

Haematologica ; 104(5): 1046-1054, 2019 05.

Artículo en Inglés | MEDLINE | ID: mdl-30545924

16.

Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells.

Karampini, Ellie; Schillemans, Maaike; Hofman, Menno; van Alphen, Floris; de Boer, Martin; Kuijpers, Taco W; van den Biggelaar, Maartje; Voorberg, Jan; Bierings, Ruben.

Haematologica ; 104(10): 2091-2099, 2019 10.

Artículo en Inglés | MEDLINE | ID: mdl-30630984

17.

Anti-HLA antibodies with complementary and synergistic interaction geometries promote classical complement activation on platelets.

Rijkers, Maaike; Schmidt, David; Lu, Nina; Kramer, Cynthia S M; Heidt, Sebastiaan; Mulder, Arend; Porcelijn, Leendert; Claas, Frans H J; Leebeek, Frank W G; Jansen, A J Gerard; Jongerius, Ilse; Zeerleder, Sacha S; Vidarsson, Gestur; Voorberg, Jan; de Haas, Masja.

Haematologica ; 104(2): 403-416, 2019 02.

Artículo en Inglés | MEDLINE | ID: mdl-30262558

18.

Generation of anti-idiotypic antibodies to detect anti-spacer antibody idiotopes in acute thrombotic thrombocytopenic purpura patients.

Schelpe, An-Sofie; Roose, Elien; Joly, Bérangère S; Pareyn, Inge; Mancini, Ilaria; Biganzoli, Marina; Deckmyn, Hans; Voorberg, Jan; Fijnheer, Rob; Peyvandi, Flora; De Meyer, Simon F; Coppo, Paul; Veyradier, Agnès; Vanhoorelbeke, Karen.

Haematologica ; 104(6): 1268-1276, 2019 06.

Artículo en Inglés | MEDLINE | ID: mdl-30523052

19.

Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells.

Schillemans, Maaike; Karampini, Ellie; van den Eshof, Bart L; Gangaev, Anastasia; Hofman, Menno; van Breevoort, Dorothee; Meems, Henriët; Janssen, Hans; Mulder, Aat A; Jost, Carolina R; Escher, Johanna C; Adam, Rüdiger; Carter, Tom; Koster, Abraham J; van den Biggelaar, Maartje; Voorberg, Jan; Bierings, Ruben.

Arterioscler Thromb Vasc Biol ; 38(7): 1549-1561, 2018 07.

Artículo en Inglés | MEDLINE | ID: mdl-29880488

20.

Inhibitors in Nonsevere Hemophilia A: What Is Known and Searching for the Unknown.

Abdi, Amal; Linari, Silvia; Pieri, Lisa; Voorberg, Jan; Fijnvandraat, Karin; Castaman, Giancarlo.

Semin Thromb Hemost ; 44(6): 568-577, 2018 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-29439277

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