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1.
rev. cuid. (Bucaramanga. 2010) ; 12(2): 1-13, mayo 1, 2021.
Artigo em Espanhol | LILACS, BDENF, COLNAL | ID: biblio-1343297

RESUMO

Introducción: El cáncer de próstata, es un problema de salud pública, la neoplasia que se diagnostica con mayor frecuencia y segunda causa de muerte en los hombres. Poco se sabe de este problema en población indígena, por lo cual, los conocimientos actuales son demandantes en la prevención primaria. Objetivo: analizar la prevalencia de sintomatología prostática y factores de riesgo entre varones indígenas, Centro, Tabasco. Material y Métodos: estudio descriptivo correlacional, diseño transversal, muestra de 281 hombres de la etnia chontal de 40 y más años de las comunidades; Tamulté de las Sabanas, Aniceto y Tocoalt. Se utilizó el cuestionario de síntomas prostáticos y entrevista de factores de riesgo. Resultados: 52.7% sin escolaridad, 47.7% son campesinos, edad media 55 años, 16.7% con sintomatología prostática de moderada a severa. Factores de riesgo; 44.5% mediano y 55.5% alto riesgo. La prueba de Chi cuadrada de Pearson entre la variable edad y sintomatología prostática tuvo una asociación de p=.000. Un valor de p=.166 entre la edad y los factores de riesgo; hombres de menor edad presentaron más factores de riesgo. Ninguno se ha realizado los exámenes de detección integral. Discusión y conclusiones: coincide con otros estudios la prevalencia de síntomas prostáticos en adultos mayores, es preocupante la prevalencia de factores de riesgo en todos los participantes, mismos que se han observado en hombres con diagnóstico de cáncer de próstata, es importante crear estrategias de prevención con miras en los estilos de vida saludable.


Introduction: Prostate cancer is a public health problem being the most frequently diagnosed neoplasm and the second leading cause of cancer death in men. However, there is little information about this disease in indigenous people and therefore, current knowledge calls for urgent primary prevention. Objective: To analyze the prevalence of prostate cancer risk factors and symptoms in indigenous men in Centro, Tabasco. Materials and Methods: A cross-sectional descriptive correlational study was conducted with 281 Chontal men aged 40 years and older from the communities of Tamulté de las Sabanas, Aniceto and Tocoalt. The Prostate Symptom Score questionnaire and interviews for assessing risk factors were both implemented. Results: 52.7% had no formal schooling at all, 47.7% were peasants at an average age of 55 years, 16.7% had moderate to severe prostatic symptoms. As for risk factors, 44.5% were classified to be at medium risk and 55.5% at high risk. Pearson's chi-squared test between variables age and prostatic symptoms showed an association of p=.000 and a value of p=.166 between age and risk factors. Younger men showed to have more risk factors associated. None had undergone comprehensive screening. Discussion and Conclusions: Prevalence of prostatic symptoms found in older adults is consistent with other studies. Prevalence of risk factors in all participants is a matter of concern as these are the same risk factors observed in men diagnosed with prostate cancer. It is important to develop prevention strategies based on healthy lifestyles.


Introdução: O câncer de próstata é um problema de saúde pública, a neoplasia mais comumente diagnosticada e segunda causa de morte nos homens. Pouco se sabe sobre este problema na população indígena, portanto, os conhecimentos atuais são exigentes na prevenção primária. Objetivo: analisar a prevalência de sintomas de próstata e fatores de risco em varões indígenas, Centro, Tabasco. Material e Métodos: estudo descritivo correlacionado, desenho transversal, amostra de 281 homens da etnia chontal com 40 anos ou mais das comunidades; Tamulté de las Sabanas, Aniceto e Tocoalt. Foram utilizados o questionário de sintomas da próstata e a entrevista de fatores de risco. Resultados: 52.7% sem escolaridade, 47.7% são camponeses, idade média de 55 anos, 16.7% com sintomas de próstata moderados a graves. Fatores de risco; 44.5% médio y 55.5% alto risco. O teste qui-quadrado de Pearson entre a variável idade e sintomas de próstata teve uma associação de p=.000. Um valor de p=.166 entre idade e os fatores de risco; homens menores de idade apresentaram mais fatores de risco. Nenhum realizou os exames de detecção abrangente. Discussão e conclusões: coincide com outros estudos a prevalência de sintomas de próstata em idosos, é preocupante a prevalência de fatores de risco em todos os participantes, o mesmo que foi observado em homens com diagnóstico de câncer de próstata, é importante criar estratégias de prevenção com vistas a estilos de vida saudáveis.


Assuntos
Humanos , Masculino , Neoplasias da Próstata , Fatores de Risco , Grupos Populacionais
2.
Rev. medica electron ; 43(1): 2822-2837, tab
Artigo em Espanhol | LILACS, CUMED | ID: biblio-1156778

RESUMO

RESUMEN Introducción: durante mucho tiempo los términos infección y sepsis han sido utilizados en forma alternativa, la tendencia actual es referirse al término infección como proceso bacteriano dependiente del germen. Objetivo: caracterizar el comportamiento de las infecciones urológicas en el servicio de urología del Hospital Universitario Comandante "Faustino Pérez Hernández", Matanzas. Materiales y métodos: se realizó un estudio observacional, descriptivo y transversal, a los pacientes atendidos en el servicio de urología del hospital Faustino Pérez, mediante el método de pesquisaje activo en el periodo comprendido desde enero de 2014 hasta diciembre de 2019. Resultados: se comprobó que la mayor parte de la población sometida a estudio es adulta mayor, predominando el sexo masculino. Entre las patologías crónicas asociadas a infecciones se encuentran la diabetes mellitus, la insuficiencia renal crónica, las inmunodeficiencias. El uso de catéteres se presentó en más de un 64% de los pacientes con infecciones. La echerichia coli fue el germen de mayor incidencia seguido de la klepsiella, pseudomonas. Conclusiones: la hiperplasia benigna de próstata, las litiasis, estenosis uretrales y los tumores uroteliales y prostático, son las principales causas obstructivas asociadas a infecciones. Un grupo importante de los pacientes operados presentaron infección del sitio quirúrgico. La sensibilidad bacteriana ante los antibióticos mostró mayor sensibilidad a meropenem, aztreonam y amikacina (AU).


Summary Introduction: the terms infection and sepsis have being alternatively used during many years; the current tendency is referring to the term infection as a germ- dependent bacterial process. Objective: to characterize the behavior of urologic infections in urological service of the University Hospital "Comandante Faustino Perez Hernandez". Materials and methods: an observational, descriptive, cross-sectional research has been made to the patients who have attended the urology service of the University Hospital "Comandante Faustino Perez Hernandez", using the method of active screening in the period from January 2014 until December 2019. Results: it was proved that the biggest part of the studied population is elder adult people, predominating the male sex. Diabetes mellitus, chronic renal failure, immunodeficiency were found among the chronic diseases associated to infections. The use of catheters was present in more than 64% of patients. Echerichia coli was the germ with highest incidence, followed by Klepsiella, andPseudomonas. Conclusions: benign prostatic hyperplasia, lithiasis, urethral stenosis, prostatic and urothelial tumors are the main obstructive causes associated to infections. An important group of patients who underwent surgery presented infections at the surgical site. Bacteria showed higher sensitivity to antibiotics like meropenem, aztreonam and amikacin (AU).


Assuntos
Humanos , Hiperplasia Prostática , Neoplasias da Próstata/etiologia , Neoplasias Uretrais/etiologia , Estreitamento Uretral , Doenças Urológicas , Fatores de Risco , Litíase , Epidemiologia Descritiva , Estudos Transversais , Diabetes Mellitus , Insuficiência Renal Crônica , Estudo Observacional
3.
Int. braz. j. urol ; 46(1): 34-41, Jan.-Feb. 2020. tab
Artigo em Inglês | LILACS | ID: biblio-1056354

RESUMO

ABSTRACT Purpose: Prostate cancer screening in the elderly is controversial. The Brazilian government and the National Cancer Institute (INCA) do not recommend systematic screening. Our purpose was to assess prevalence and aggressiveness of prostate cancer in men aged 70 years and above, on the first Latin American database to date. Materials and Methods: Cross-sectional study (n=17,571) from 231 municipalities, visited by Mobile Cancer Prevention Units of a prostate-specific antigen (PSA) based opportunistic screening program, between 2004 and 2007. The criteria for biopsy were: PSA>4.0ng/ml, or PSA 2.5-4.0ng/ml with free/total PSA ratio ≤15%, or suspicious digital rectal examination findings. The screened men were stratified in two age groups (45-69 years, and ≥70 years). These groups were compared regarding prostate cancer prevalence and aggressiveness criteria (PSA, Gleason score from biopsy and TNM staging). Results: The prevalence of prostate cancer found was 3.7%. When compared to men aged 45-69 years, individuals aged 70 years and above presented cancer prevalence about three times higher (prevalence ratio 2.9, p<0.01), and greater likelihood to present PSA level above 10.0ng/ml at diagnosis (odds ratio 2.63, p<0.01). The group of elderly men also presented prevalence of histologically aggressive disease (Gleason 8-10) 3.6 times higher (p<0.01), and 5-fold greater prevalence of metastases (PR 4.95, p<0.05). Conclusions: Prostate cancer screening in men aged over 70 may be relevant in Brazil, considering the absence of systematic screening, higher prevalence and higher probability of high-risk disease found in this age range of the population studied.


Assuntos
Humanos , Masculino , Idoso , Idoso de 80 Anos ou mais , Neoplasias da Próstata/diagnóstico , Neoplasias da Próstata/epidemiologia , Programas de Rastreamento/métodos , Neoplasias da Próstata/patologia , Biópsia , Brasil/epidemiologia , Prevalência , Estudos Transversais , Fatores de Risco , Fatores Etários , Antígeno Prostático Específico/sangue , Medição de Risco , Exame Retal Digital , Detecção Precoce de Câncer , Gradação de Tumores , Pessoa de Meia-Idade , Estadiamento de Neoplasias
4.
Int. braz. j. urol ; 46(1): 42-52, Jan.-Feb. 2020. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1056364

RESUMO

ABSTRACT Introduction: Tables predicting the probability of a positive bone scan in men with non-metastatic, castrate-resistant prostate cancer have recently been reported. We performed an external validation study of these bone scan positivity tables. Materials and Methods: We performed a retrospective cohort study of patients seen at a tertiary care medical center (1996-2012) to select patients with non-metastatic, castrate-resistant prostate cancer. Abstracted data included demographic, anthropometric, and disease-specific data such as patient race, BMI, PSA kinetics, and primary treatment. Primary outcome was metastasis on bone scan. Multivariable logistic regression was performed using generalized estimating equations to adjust for repeated measures. Risk table performance was assessed using ROC curves. Results: We identified 6.509 patients with prostate cancer who had received hormonal therapy with a post-hormonal therapy PSA ≥2ng/mL, 363 of whom had non-metastatic, castrate-resistant prostate cancer. Of these, 187 patients (356 bone scans) had calculable PSA kinetics and ≥1 bone scan. Median follow-up after castrate-resistant prostate cancer diagnosis was 32 months (IQR: 19-48). There were 227 (64%) negative and 129 (36%) positive bone scans. On multivariable analysis, higher PSA at castrate-resistant prostate cancer (4.67 vs. 4.4ng/mL, OR=0.57, P=0.02), shorter time from castrate-resistant prostate cancer to scan (7.9 vs. 14.6 months, OR=0.97, P=0.006) and higher PSA at scan (OR=2.91, P <0.0001) were significantly predictive of bone scan positivity. The AUC of the previously published risk tables for predicting scan positivity was 0.72. Conclusion: Previously published risk tables predicted bone scan positivity in men with non-metastatic, castrate-resistant prostate cancer with reasonable accuracy.


Assuntos
Humanos , Masculino , Idoso , Neoplasias Ósseas/secundário , Neoplasias Ósseas/diagnóstico por imagem , Neoplasias de Próstata Resistentes à Castração/patologia , Neoplasias de Próstata Resistentes à Castração/diagnóstico por imagem , Valores de Referência , Fatores de Tempo , Osso e Ossos/diagnóstico por imagem , Modelos Logísticos , Valor Preditivo dos Testes , Estudos Retrospectivos , Fatores de Risco , Curva ROC , Antígeno Prostático Específico/sangue , Medição de Risco , Gradação de Tumores , Pessoa de Meia-Idade
5.
Int. braz. j. urol ; 45(6): 1105-1112, Nov.-Dec. 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1056339

RESUMO

ABSTRACT Purpose: To compare the treatment outcomes of a cohort of prostate cancer patients treated with conventional schedule using IMRT or 3DRT technique. Materials and Methods: Between 2010-2017, 485 men with localized prostate cancer were treated with conventional radiotherapy schedule with a total dose ≥74Gy using IMRT (231) or 3DCRT (254). Late gastrointestinal (GI) and genitourinary (GU) toxicity were retrospectively evaluated according to modified RTOG criteria. The biochemical control was defined by the Phoenix criteria (nadir + 2ng/mL). The comparison between the groups included biochemical recurrence free survival (bRFS), overall survival (OS) and late toxicity. Results: With a median follow-up of 51 months (IMRT=49 and 3DRT=51 months), the maximal late GU for >=grade- 2 during the entire period of follow-up was 13.1% in the IMRT and 15.4% in the 3DRT (p=0.85). The maximal late GI ≥ grade- 2 in the IMRT was 10% and in the 3DRT 24% (p=0.0001). The 5-year bRFS for all risk groups with IMRT and 3D-CRT was 87.5% vs. 87.2% (p=0.415). Considering the risk-groups no significant difference for low-, intermediate- and high-risk groups between IMRT (low-95.3%, intermediate-86.2% and high-73%) and 3D-CRT (low-96.4%, intermediate-88.2% and high-76.6%, p=0.448) was observed. No significant differences for OS and DMFS were observed comparing treatment groups. Conclusion: IMRT reduces significantly the risk of late GI severe complication compared with 3D-CRT using conventional fractionation with a total dose ≥74Gy without any differences for bRFS and OS.


Assuntos
Humanos , Masculino , Idoso , Neoplasias da Próstata/radioterapia , Radioterapia Conformacional/métodos , Radioterapia de Intensidade Modulada/métodos , Neoplasias da Próstata/mortalidade , Neoplasias da Próstata/patologia , Lesões por Radiação , Dosagem Radioterapêutica , Fatores de Tempo , Sistema Urogenital/efeitos da radiação , Estudos Retrospectivos , Fatores de Risco , Medição de Risco , Intervalo Livre de Doença , Radioterapia Conformacional/efeitos adversos , Trato Gastrointestinal/efeitos da radiação , Relação Dose-Resposta à Radiação , Radioterapia de Intensidade Modulada/efeitos adversos , Estimativa de Kaplan-Meier , Gradação de Tumores , Pessoa de Meia-Idade
6.
Int. braz. j. urol ; 45(4): 724-731, July-Aug. 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1019880

RESUMO

ABSTRACT Objectives To evaluate the diagnostic performance and interobserver agreement of PI-RADS v2. Materials and Methods In this Institutional Review Board approved single-center retrospective study, 98 patients with clinically suspected PCa who underwent 3-T multiparametric MRI followed by MRI/TRUS fusion-guided prostate biopsy were included from June 2013 to February 2015. Two radiologists (R1 and R2) with 8 and 1 years of experience in abdominal radiology reviewed the MRI scans and assigned PI-RADS v2 scores in all prostate zones. PI-RADS v2 were compared to MRI/TRUS fusion-guided biopsy results, which were classified as negative, PCa, and significant PCa (sPCa). Results Sensitivity, specificity, NPV, PPV and accuracy for PCa was 85.7% (same for all metrics) for R1 and 81.6%, 79.6%, 81.2%, 80.0% and 80.6% for R2. For detecting sPCa, the corresponding values were 95.3%, 85.4%, 95.9%, 83.7% and 89.8% for R1 and 93.0%, 81.8%, 93.7%, 86.7% and 86.7% for R2. There was substantial interobserver agreement in assigning PI-RADS v2 score as negative (1, 2, 3) or positive (4, 5) (Kappa=0.78). On multivariate analysis, PI-RADS v2 (p <0.001) was the only independent predictor of sPCa compared with age, abnormal DRE, prostate volume, PSA and PSA density. Conclusions Our study population demonstrated that PI-RADS v2 had high diagnostic accuracy, substantial interobserver agreement, and it was the only independent predictor of sPCa.


Assuntos
Humanos , Masculino , Idoso , Neoplasias da Próstata/diagnóstico por imagem , Imageamento por Ressonância Magnética/métodos , Neoplasias da Próstata/patologia , Valores de Referência , Brasil , Modelos Logísticos , Variações Dependentes do Observador , Reprodutibilidade dos Testes , Estudos Retrospectivos , Fatores de Risco , Sensibilidade e Especificidade , Antígeno Prostático Específico/sangue , Estatísticas não Paramétricas , Medição de Risco , Gradação de Tumores , Biópsia Guiada por Imagem/métodos , Pessoa de Meia-Idade
7.
Medicina (Ribeiräo Preto) ; 52(2)abr.-jun., 2019.
Artigo em Inglês | LILACS | ID: biblio-1025051

RESUMO

Background: Prostate cancer is the second most incident of the male population in Brazil. The aim of this study is to analyze the frequency of risk factors associated to the evolution of the prostate cancer and the impact of conducting examinations in the age range (55-69 years old), in assisting health professionals to manage and prevent the disease. Methods: A case-control study was performed on patients from 2011 to 2016 in Criciúma ­ SC, Brazil. The sample was divided into two groups, one with biopsy for prostate adenocarcinoma (case; n = 124) and the other with a negative biopsy (control; n = 251). The following variables were compared between the two groups: age, family history of prostate cancer, prostate specific antigen, and altered digital rectal examination. Results: In the case group, ranging between 55-69 years old, there was a significant higher of altered digital rectal examination (p < 0.001, odds ratio 15.5 and positive predictive value 91.3%), prostate-specific antigen ≥ 4 ng/mL (p < 0.001, odds ratio 7.02 and positive predictive value 56.2%) and when both exams were altered (p < 0.001, odds ratio was 19.63 and the positive predictive value was 90.5%). Conclusion: This findings show that, mainly between 55-69 years old, there is a significant correlation between positive biopsy, altered digital rectal examination, and PSA ≥ 4 ng/mL (AU)


Objetivo: O câncer de próstata é o segundo mais incidente na população masculina no Brasil. O objetivo do estudo é analisar a frequência dos fatores de risco associados ao desenvolvimento do câncer de próstata e o impacto da realização de exames na faixa etária de rastreamento (55-69 anos), auxiliando os profissionais de saúde no manejo e prevenção da doença. Método: Foi realizado um estudo caso-controle no período de 2011 a 2016 em Criciúma ­ SC, Brasil. A amostra foi dividida em dois grupos, um com biópsia de adenocarcinoma de próstata (casos; n = 124) e outro com biópsia negativa (controles; n = 251). Entre ambos os grupos, foram comparadas as variáveis: idade, história familiar de câncer de próstata, antígeno prostático específico e toque retal alterado. Resultados:No grupo dos casos, na faixa etária entre 55-69 anos, ocorreu maior significância de toque retal alterado (p < 0,001; odds ratio 15.5 e valor preditivo positivo 91,3%), antígeno prostático específico ≥ 4 ng/mL (p < 0,001; odds ratio 7.02 e valor preditivo positivo 56,2%) e quando os dois exames estavam alterados (p < 0,001; odds ratio 19.63 e valor preditivo positivo 90,5%). Conclusão: Há evidências, principalmente entre 55-69 anos, de maior correlação de biópsia positiva, toque retal alterado e PSA ≥ 4 ng/mL (AU)


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Neoplasias da Próstata , Fatores de Risco , Exame Retal Digital , Homólogo AlkB 3 da Dioxigenase Dependente de alfa-Cetoglutarato
10.
Int. braz. j. urol ; 45(3): 468-477, May-June 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1012330

RESUMO

ABSTRACT Introduction: To determine the impact of time from biopsy to surgery on outcomes following radical prostatectomy (RP) as the optimal interval between prostate biopsy and RP is unknown. Material and methods: We identified 7, 350 men who underwent RP at our institution between 1994 and 2012 and had a prostate biopsy within one year of surgery. Patients were grouped into five time intervals for analysis: ≤ 3 weeks, 4-6 weeks, 7-12 weeks, 12-26 weeks, and > 26 weeks. Oncologic outcomes were stratified by NCCN disease risk for comparison. The associations of time interval with clinicopathologic features and survival were evaluated using multivariate logistic and Cox regression analyses. Results: Median time from biopsy to surgery was 61 days (IQR 37, 84). Median follow-up after RP was 7.1 years (IQR 4.2, 11.7) while the overall perioperative complication rate was 19.7% (1,448/7,350). Adjusting for pre-operative variables, men waiting 12-26 weeks until RP had the highest likelihood of nerve sparing (OR: 1.45, p = 0.02) while those in the 4-6 week group had higher overall complications (OR: 1.33, p = 0.01). High risk men waiting more than 6 months had higher rates of biochemical recurrence (HR: 3.38, p = 0.05). Limitations include the retrospective design. Conclusions: Surgery in the 4-6 week time period after biopsy is associated with higher complications. There appears to be increased biochemical recurrence rates in delaying RP after biopsy, for men with both low and high risk disease.


Assuntos
Humanos , Masculino , Idoso , Complicações Pós-Operatórias/etiologia , Prostatectomia/efeitos adversos , Neoplasias da Próstata/cirurgia , Neoplasias da Próstata/patologia , Tempo para o Tratamento , Complicações Intraoperatórias/etiologia , Prostatectomia/métodos , Fatores de Tempo , Biópsia , Modelos Logísticos , Estudos Retrospectivos , Fatores de Risco , Análise de Variância , Resultado do Tratamento , Antígeno Prostático Específico/sangue , Medição de Risco , Progressão da Doença , Gradação de Tumores , Pessoa de Meia-Idade , Recidiva Local de Neoplasia , Estadiamento de Neoplasias
11.
Int. braz. j. urol ; 45(3): 495-502, May-June 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1012326

RESUMO

ABSTRACT Background: Our study investigates whether Native Thiol, Total Thiol and disulphide levels measured in serum of patients with prostate cancer and prostatitis and of healthy subjects, have any role in differential diagnosis. Materials and Methods: Patients followed up for histopathologically verified diagnosis of prostate cancer and prostatitis in 2016-2017 at the Medicalpark Gaziantep Hospital Urology Clinic were included in the study. Native Thiol (NT), Total Thiol (TT), Dynamic Disulphide (DD) levels in serum were measured by a novel automated method. Results: NT, TT, DD, NT / TT ratios, DD / TT ratio and DD / NT ratio were measured as 118.4 ± 36.8μmoL / L, 150.3 ± 45.3μmoL / L, 15.9 ± 7μmoL / L, 78.8 ± 7μmoL / L, 10.5 ± 3.5μmoL / L, 13.8 ± 5.8μmoL / L respectively in patients with prostate cancer; as 116.4 ± 40.5μmoL / L, 147.5 ± 50.1μmoL / L, 15.5 ± 8.7μmoL / L, 79.7 ± 9μmoL / L, 10.1 ± 4.5μmoL / L, 13.5 ± 7.2μmoL / L in patients with prostatitis and as 144.1 ± 21.2μmoL / L, 191 ± 32.3μmoL / L, 23.4 ± 10.1μmoL / L, 76.1 ± 98.3μmoL / L, 11.9 ± 4.1μmoL / L, 16.4 ± 6.9μmoL / L in healthy subjects. Significant difference was detected between groups of NT, TT and DD levels (p = 0.008, p = 0.001, p = 0.002). No significant difference was detected in terms of the NT / TT, DD / TT and DD / NT rates (p = 0.222, p = 0.222, p = 0.222). Conclusions: Serum NT, TT, DD levels in patients with prostatitis and prostate cancer were found significantly lower compared to the control group. This indicates that just as inflammation, prostate cancer also increases oxidative stress on tissues.


Assuntos
Humanos , Masculino , Idoso , Neoplasias da Próstata/sangue , Prostatite/sangue , Compostos de Sulfidrila/sangue , Dissulfetos/sangue , Neoplasias da Próstata/diagnóstico , Prostatite/diagnóstico , Valores de Referência , Biomarcadores Tumorais/sangue , Estudos de Casos e Controles , Reprodutibilidade dos Testes , Estudos Retrospectivos , Fatores de Risco , Análise de Variância , Estatísticas não Paramétricas , Medição de Risco , Estresse Oxidativo/fisiologia , Diagnóstico Diferencial , Pessoa de Meia-Idade
12.
Int. braz. j. urol ; 45(3): 486-494, May-June 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1012318

RESUMO

ABSTRACT Objectives: To identify the group of patients who could safely avoid prostate biopsy based on the findings of multiparametric prostate resonance imaging (MRmp), parameterized with PI-RADS v2, using prostate biopsy as reference test and to assess the sensitivity and specificity of mpMR in identifying clinically significant prostate cancer using prostate biopsy as a reference test. Patients and Methods: Three hundred and forty two patients with suspected prostate cancer were evaluated with mpMR and prostate biopsy. Agreement between imaging findings and histopathological findings was assessed using the Kappa index. The accuracy of mpMR in relation to biopsy was assessed by calculations of sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV). Results: A total of 342 biopsies were performed. In 201 (61.4%), mpMR had a negative result for cancer, which was confirmed on biopsy in 182 (53%) of the cases, 17 (4.9%) presented non-clinically significant cancer and only 2 (0.5%) clinically significant cancer. 131 (38.3%) patients had a positive biopsy. Clinically significant cancer corresponded to 83 (34.2%), of which 81 (97.5%) had a positive result in mpMR. Considering only the clinically significant cancers the mpMR had a sensitivity of 97.6%, specificity of 76.8%, PPV 57.4% and VPN of 99%. Conclusions: mpMR is a useful tool to safely identify which patients at risk for prostate cancer need to undergo biopsy and has high sensitivity and specificity in identifying clinically significant prostate cancer.


Assuntos
Humanos , Masculino , Feminino , Adulto , Idoso , Idoso de 80 Anos ou mais , Próstata/patologia , Próstata/diagnóstico por imagem , Neoplasias da Próstata/patologia , Neoplasias da Próstata/diagnóstico por imagem , Imageamento por Ressonância Magnética/métodos , Biópsia Guiada por Imagem/métodos , Padrões de Referência , Reprodutibilidade dos Testes , Estudos Retrospectivos , Fatores de Risco , Sensibilidade e Especificidade , Gradação de Tumores , Pessoa de Meia-Idade
13.
Nursing (Säo Paulo) ; 22(251): 2904-2909, abr.2019.
Artigo em Português | LILACS, BDENF | ID: biblio-998862

RESUMO

Objetiva-se desvelar o vivido do homem após o diagnóstico de câncer de próstata. Pesquisa qualitativa utilizando a abordagem teórico-filosófico-metodológico de Martin Heidegger. Foi cenário um Hospital de Ensino da Zona da Mata Mineira e participaram quinze homens que receberam o diagnóstico de câncer de próstata. Os depoimentos foram colhidos, de outubro a dezembro 2014, por meio da entrevista fenomenológica. Desvelou-se que o homem sente-se ameaçado pela doença e por suas consequências, desenvolvendo o movimento da angústia imprópria apresentando o temor, pavor, horror e terror. O ser-aí-apósdiagnóstico-de-câncer-de-próstata, lançado na sua facticidade, expressa um movimento de inautenticidade determinado pelo impessoal, exposto ao falatório e à ambiguidade. Enfatiza-se a contribuição para a melhoria da qualidade da assistência ao homem, ratificando ser necessário atender não somente à dimensão física, mas aos aspectos emocionais, sociais e espirituais, frente às atuais Políticas Públicas de Saúde do Homem.(AU)


It is intended to reveal the experience of man after the diagnosis of prostate cancer. Qualitative research using the theoretical-philosophical-methodological approach of Martin Heidegger. A teaching hospital in the Zona da Mata Mineira was set up and fifteen men who were diagnosed with prostate cancer participated. The testimonies were collected, from October to December 2014, through the phenomenological interview. It has been revealed that man feels threatened by disease and its consequences, developing the movement of impropriety presenting fear, dread, horror and terror. The being-there-after-diagnosis-of-prostate cancer, launched in its facticity, expresses a movement of inauthenticity determined by the impersonal, exposed to talk and ambiguity. Emphasis is given to the contribution to improving the quality of care for men, confirming the need to address not only the physical dimension, but also the emotional, social and spiritual aspects, in face of the current Public Health Policies of Man.(AU)


Se pretende desvelar lo vivido del hombre tras el diagnóstico de cáncer de próstata. Investigación cualitativa utilizando el enfoque teórico-filosófico-metodológico de Martin Heidegger. Fue escenario un Hospital de Enseñanza de la Zona de la Mata Minera y participaron quince hombres que recibieron el diagnóstico de cáncer de próstata. Los testimonios fueron recolectados, de octubre a diciembre de 2014, por medio de la entrevista fenomenológica. Se desveló que el hombre se siente amenazado por la enfermedad y por sus consecuencias, desarrollando el movimiento de la angustia inapropiada presentando el temor, pavor, horror y terror. El serahí-después-diagnóstico-de-cáncer de próstata, lanzado en su facticidad, expresa un movimiento de inautenticidad determinado por el impersonal, expuesto al falatorio ya la ambigüedad. Enfatiza la contribución a la mejora de la calidad de la asistencia al hombre, ratificando que es necesario atender no sólo a la dimensión física, sino a los aspectos emocionales, sociales y espirituales, frente a las actuales Políticas Públicas de Salud del Hombre.(AU)


Assuntos
Humanos , Masculino , Neoplasias da Próstata , Saúde do Homem , Detecção Precoce de Câncer , Fatores de Risco , Promoção da Saúde
14.
J. coloproctol. (Rio J., Impr.) ; 39(2): 159-162, Apr.-June 2019. tab
Artigo em Inglês | LILACS | ID: biblio-1012598

RESUMO

ABSTRACT Introduction: Colorectal carcinoma is commonest cancer of gastrointestinal tract. It is represent third cancer in man worldwide beyond lung and prostate cancers. It is fourth cancer in woman beyond breast, lung and uterus cancers. Deaths from colorectal cancer are more in compare with other GIT cancers. Objective: The aim is prove epidemiological and clinical data of colorectal cancer. Method: Our study conducted in Misan Province, Iraq. The data collected from 2013 to 2016. Seventy one patients that found have colorectal cancer. Gender, age, residency, site of cancer, family history, past history, year of onset, smoking history, alcohol intake, presentation, staging and histopathology pattern are get. Results: Prevalence of colon and rectum carcinoma is 3.75%. The most age group affected was 51-60 years as 30.99%. The gender and residency of patients have no effect on cancer percent. Obesity, Family history, cigarette smoking and alcohol consumption risk factors. In 42.25% of patients had family history of cancer. Conclusion: Most common site of colorectal carcinoma left colon, which present in 61.97%. There is increase in new cases detection of colorectal carcinoma from 2013 to 2016. Advanced stages cancer were most common stages description as IIIA, IIIB, IIIC and IV in 12.67%, 16.90%, 19.72% and 15.49%. The common histopathological pattern is differentiated adenocarcinoma as 53.52%.


RESUMO Introdução: O carcinoma colorretal é o câncer mais comum do trato gastrointestinal. É o terceiro tipo de câncer mais observado no sexo masculino mundialmente, atrás dos cânceres de pulmão e próstata. É o quarto câncer mais observado no sexo feminino, atrás dos cânceres de mama, pulmão e útero. As mortes por câncer colorretal são mais comuns comparadas a outros cânceres do TGI. Objetivo: O objetivo do estudo é comprovar dados epidemiológicos e clínicos do câncer colorretal. Métodos: Nosso estudo foi conduzido na província de Misan, no Iraque. Os dados foram coletados de 2013 a 2016. Setenta e um pacientes apresentaram câncer colorretal. Sexo, idade, local de residência, local do câncer, história familiar, história pregressa, ano de início, história de tabagismo, etilismo, apresentação, estadiamento e padrão histopatológico foram obtidos. Resultados: A prevalência de carcinoma de cólon e reto é de 3,75%. A faixa etária mais afetada foi de 51 a 60 anos, com 30,99%. O gênero e o local de residência dos pacientes não afetam a porcentagem de ocorrência do câncer. Obesidade, antecedentes familiares, tabagismo e consumo de álcool são fatores de risco. 42,25% dos pacientes tinha história familiar de câncer. Conclusão: O local mais comum de carcinoma colorretal é o cólon esquerdo, com 61,97%. Houve aumento na detecção de novos casos de carcinoma colorretal de 2013 a 2016. Os estágios avançados de câncer mais comuns foram IIIA, IIIB, IIIC e IV em 12,67%, 16,90%, 19,72% e 15,49% dos casos. O padrão histopatológico comum é o adenocarcinoma diferenciado, em 53,52% dos casos.


Assuntos
Humanos , Neoplasias Colorretais/epidemiologia , Doenças do Colo , Fatores de Risco , Iraque
15.
Int. braz. j. urol ; 45(2): 306-314, Mar.-Apr. 2019. tab
Artigo em Inglês | LILACS | ID: biblio-1002215

RESUMO

ABSTRACT Purpose: Non - muscle - invasive bladder cancer (NMIBC) can recur despite transurethral resection (TURBT) and adjuvant intravesical therapy. Tobacco products excreted in the urine are hypothesized to cause tumor - promoting effects on urothelial cells through direct contact. We determined if moderate or severe lower urinary tract symptoms (LUTS) (defined as International Prostate Symptom Score [IPSS] ≥ 8) was associated with increased tumor recurrence. Materials and Methods: We retrospectively identified 70 consecutive men initially diagnosed with NMIBC at our institution from 2010 - 2016. Means were compared with independent T - test and proportions with chi - square analysis. Multivariate logistic regression was performed to determine independent predictors of recurrence. Results: The majority of patients had Ta disease (58.6%) followed by T1 (28.6%) and Tis (12.9%). Forty - one (58.6%) patients had moderate or severe LUTS upon presentation within 30 days of initial TURBT with mean IPSS of 13.2 vs. 5.2 in the control group (p < 0.01). Biopsy - proven tumor recurrence occurred in 24 (34.3%) patients at mean follow-up of 31.7 months. Mean time to recurrence was 14.6 months. Moderate or severe LUTS was an independent predictor of tumor recurrence (odds ratio [OR]: 19.1, 95% confidence interval [CI]: 2.86 - 127; p = 0.002). Voiding or storage symptoms based on the IPSS did not independently correlate with tumor recurrence (p = 0.08 and p = 0.31, respectively) although total mean IPSS score did (OR: 1.26, 95% CI: 1.07 - 1.47, p = 0.005). Conclusions: The presence of moderate or severe LUTS may be an important prognostic factor in NMIBC. Patients with significant urinary symptoms could be monitored more aggressively due to higher recurrence risk.


Assuntos
Humanos , Masculino , Idoso , Hiperplasia Prostática/complicações , Bexiga Urinária/patologia , Neoplasias da Bexiga Urinária/patologia , Sintomas do Trato Urinário Inferior/etiologia , Recidiva Local de Neoplasia/patologia , Qualidade de Vida , Biópsia , Estudos Retrospectivos , Fatores de Risco , Seguimentos , Progressão da Doença , Pessoa de Meia-Idade
16.
Int. braz. j. urol ; 45(2): 220-228, Mar.-Apr. 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1002214

RESUMO

ABSTRACT Obesity is defined as a chronic and excessive growth of adipose tissue. It has been associated with a high risk for development and progression of obesity-associated malignancies, while adipokines may mediate this association. Adiponectin is an adipose tissue-derived adipokines, with significant anti-diabetic, anti-inflammatory, anti-atherosclerotic and anti-proliferative properties. Plasma adiponectin levels are decreased in obese individuals, and this feature is closely correlated with development of several metabolic, immunological and neoplastic diseases. Recent studies have shown that prostate cancer patients have lower serum adiponectin levels and decreased expression of adiponectin receptors in tumor tissues, which suggests plasma adiponectin level is a risk factor for prostate cancer. Furthermore, exogenous adiponectin has exhibited therapeutic potential in animal models. In this review, we focus on the potential role of adiponectin and the underlying mechanism of adiponectin in the development and progression of prostate cancer. Exploring the signaling pathways linking adiponectin with tumorigenesis might provide a potential target for therapy.


Assuntos
Humanos , Animais , Masculino , Neoplasias da Próstata/sangue , Adiponectina/sangue , Receptores de Adiponectina/sangue , Neoplasias da Próstata/etiologia , Neoplasias da Próstata/patologia , Tecido Adiposo , Fatores de Risco , Progressão da Doença , Modelos Animais de Doenças , Obesidade/complicações
17.
Int. braz. j. urol ; 45(2): 273-287, Mar.-Apr. 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1002208

RESUMO

ABSTRACT Introduction: Several recent randomized clinical trials have evaluated hypofractionated regimens against conventionally fractionated EBRT and shown similar effectiveness with conflicting toxicity results. The current view regarding hypofractionation compared to conventional EBRT among North American genitourinary experts for management of prostate cancer has not been investigated. Materials and Methods: A survey was distributed to 88 practicing North American GU physicians serving on decision - making committees of cooperative group research organizations. Questions pertained to opinions regarding the default EBRT dose and fractionation for a hypothetical example of a favorable intermediate - risk prostate cancer (Gleason 3 + 4). Treatment recommendations were correlated with practice patterns using Fisher's exact test. Results: Forty - two respondents (48%) completed the survey. We excluded from analysis two respondents who selected radical hypofractionation with 5 - 12 fractions as a preferred treatment modality. Among the 40 analyzed respondents, 23 (57.5%) recommend conventional fractionation and 17 (42.5%) recommended moderate hypofractionation. No demographic factors were found to be associated with preference for a fractionation regimen. Support for brachytherapy as a first choice treatment modality for low - risk prostate cancer was borderline significantly associated with support for moderate hypofractionated EBRT treatment modality (p = 0.089). Conclusions: There is an almost equal split among North American GU expert radiation oncologists regarding the appropriateness to consider moderately hypofractionated EBRT as a new standard of care in management of patients with prostate cancer. Physicians who embrace brachytherapy may be more inclined to support moderate hypofractionated regimen for EBRT. It is unclear whether reports with longer follow-ups will impact this balance, or whether national care and reimbursement policies will drive the clinical decisions. In the day and age of patient - centered care delivery, patients should receive an objective recommendation based on available clinical evidence. The stark division among GU experts may influence the design of future clinical trials utilizing EBRT for patients with prostate cancer.


Assuntos
Humanos , Masculino , Neoplasias da Próstata/radioterapia , Braquiterapia/métodos , Radioterapia (Especialidade)/normas , Hipofracionamento da Dose de Radiação/normas , Neoplasias da Próstata/patologia , Estados Unidos , Braquiterapia/normas , Ensaios Clínicos Controlados Aleatórios como Assunto , Fatores de Risco , Radioterapia (Especialidade)/métodos , Gradação de Tumores
18.
Int. braz. j. urol ; 45(2): 237-245, Mar.-Apr. 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1002192

RESUMO

ABSTRACT Objective: To build a model to evaluate the impact of salvage radiotherapy (SRT) in men with PSA rise or persistent PSA after undergoing radical prostatectomy (RP). Materials and Methods: The study included 107 node-negative patients treated with SRT after RP at a single institution. Patients received SRT for either prostate-specific antigen (PSA) rising, or PSA persistence after RP. All patients received local radiation to the prostate / seminal vesicle bed. The primary measured outcome was the biochemical recurrence (BCR) free survival. Multivariable Cox regression analysis was used to develop a risk-stratification group to identify predictive factors associated with the probability of BCR at 5yr. Results: At a median follow-up of 52 months, the BCR free survival rate and overall survival in 5 years was 73% and 94%, respectively. At multivariable analysis, pre-SRT PSA level > 0.35ng / mL (p = 0.023), negative margins (p = 0.038), and seminal vesicles invasion (p = 0.001) were significantly associated with BCR free survival. Three risk groups using regression analysis for SRT administration was built. Low-, intermediate- and the high-risk groups had a BCR free survival in 5-years of 96%, 84%, and 44% (p = 0.0001), respectively. Conclusions: We developed a risk group stratification to show the impact of SRT based on prostate cancer characteristics. SRT showed to be extremely beneficial for patients with low- and intermediate-risk tumors. Moreover, the risk-group built could identify patients classified as high-risk who might benefit from more aggressive treatment for SRT.


Assuntos
Humanos , Masculino , Idoso , Prostatectomia , Neoplasias da Próstata/cirurgia , Terapia de Salvação/efeitos adversos , Recidiva Local de Neoplasia/radioterapia , Neoplasias da Próstata/patologia , Neoplasias da Próstata/radioterapia , Dosagem Radioterapêutica , Taxa de Sobrevida , Estudos Retrospectivos , Fatores de Risco , Seguimentos , Antígeno Prostático Específico/sangue , Intervalo Livre de Doença , Intervenção Médica Precoce , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/patologia , Estadiamento de Neoplasias
19.
Cad. Saúde Pública (Online) ; 35(5): e00143818, 2019. tab
Artigo em Português | LILACS | ID: biblio-1001663

RESUMO

O objetivo do estudo foi estimar a mortalidade por câncer em povos indígenas no Estado do Acre, Brasil. Trata-se de estudo observacional descritivo, com base no banco nominal do SIM (Sistema de Informações sobre Mortalidade), referente ao período de 1º de janeiro de 2000 a 31 de dezembro de 2012. Foi analisada a distribuição de frequência de óbitos, por sexo e faixa etária, e calculada a RMP (razão de mortalidade padronizada), tendo como referência Goiânia (Goiás), Acre e Região Norte. Foram identificados 81 óbitos, a maioria de homens (59,3%) e acima de 70 anos. As cinco principais localizações em homens foram estômago, fígado, cólon e reto, leucemia e próstata. Nas mulheres, câncer cervical, estômago, fígado, leucemia e útero. Nos homens indígenas houve excesso de óbitos por câncer de estômago quando comparados às populações de Goiânia (RMP = 2,72; 2,58-2,87), Acre (RMP = 2,05; 1,94-2,16) e Região Norte (RMP = 3,10; 2,93-3,27). O mesmo foi observado para óbitos por hepatocarcinomas, tendo por referência Goiânia (RMP = 3,89; 3,66-4,14), Acre (RMP = 1,79; 1,68-1,91) e Região Norte (RMP = 4,04; 3,77-4,30). Dentre as mulheres indígenas, destaca-se o excesso de câncer cervical em relação à Goiânia (RMP = 4,67; 4,41-4,93), Acre (RMP = 2,12; 2,00-2,24) e Região Norte (RMP = 2,60; 2,45-2,75). As estimativas apontam que neoplasias passíveis de prevenção, como câncer cervical, e ligadas ao subdesenvolvimento, como estômago e fígado, corresponderam a cerca de 49,4% dos óbitos entre indígenas. Comparados à população de referência, a mortalidade por câncer de fígado, estômago, colorretal e leucemias foi maior que o dobro entre os homens indígenas; por câncer cervical, estômago, fígado e leucemias esteve acima de 30% entre as mulheres indígenas.


The study aimed to estimate cancer mortality among indigenous peoples in Acre State, Brazil. This was a descriptive observational study based on the nominal bank of the Brazilian Mortality Information System for the period from January 1st, 2000, to December 31st, 2012. The study analyzed the distribution death frequencies by sex and age. Standardized mortality ratio (SMR) was calculated taking Goiânia (Goiás State), Acre State, and the North Region of Brazil as the references. A total of 81 deaths were identified, the majority in men (59.3%) and in individuals over 70 years of age. The five main sites in men were stomach, liver, colon and rectum, leukemia, and prostate. The five main sites in women were uterine cervix, stomach, liver, leukemia, and uterus. In indigenous men there was an excess of deaths from stomach cancer compared to the populations of Goiânia (SMR = 2.72; 2.58-2.87), Acre State (SMR = 2.05; 1.94-2.16) and North region (SMR = 3.10; 2.93-3.27). The same was observed for deaths from hepatic cell carcinomas referenced against Goiânia (SMR = 3.89; 3.66-4.14), Acre State (SMR = 1.79; 1.68-1.91), and the North of Brazil (SMR = 4.04; 3.77-4.30). Among indigenous women, there was an excess of cervical cancer in comparison to Goiânia (SMR = 4.67; 4.41-4.93), Acre State (SMR = 2.12; 2.00-2.24), and the North (SMR = 2.60; 2.45-2.75). The estimates show that preventable neoplasms such as cervical cancer and those linked to underdevelopment, such as stomach and liver cancer, account for 49.4% of deaths among indigenous peoples. Compared to the reference population, mortality from liver, stomach, and colorectal cancer and leukemias was more than twice as high in indigenous men; among indigenous women, cervical, stomach, and liver cancer and leukemias were 30% higher.


El objetivo del estudio fue estimar la mortalidad por cáncer en pueblos indígenas del estado de Acre. Se trata de un estudio observacional descriptivo, a partir del banco de datos nominal del SIM (Sistema de Información Sobre Mortalidad), referente al período de 01 de enero de 2000 a 31 de diciembre de 2012. Se analizó la distribución de frecuencia de óbitos, por sexo y franja de edad, y se calculó la RMP (razón de mortalidad estandarizada), teniendo como referencia Goiânia-GO, Acre y la región norte. Se identificaron 81 óbitos, la mayoría en hombres (59,3%) y por encima de los 70 años. Los cinco principales focos en hombres fueron: estómago, hígado, colon y recto, leucemia y próstata. En las mujeres, cáncer cervical, estómago, hígado, leucemia y útero. En los hombres indígenas, hubo exceso de óbitos por cáncer de estómago, comparados con las poblaciones de Goiânia (RMP = 2,72; 2,58-2,87), estado de Acre (RMP = 2,05; 1,94-2,16) y región norte (RMP = 3,10; 2,93-3,27). Lo mismo se observó en caso de óbitos por hepatocarcinomas, teniendo por referencia Goiânia (RMP = 3,89; 3,66-4,14), estado de Acre (RMP = 1,79; 1,68-1,91) y región norte (RMP = 4,04; 3,77-4,30). Entre las mujeres indígenas, se destaca el exceso de cáncer cervical, en relación con Goiânia (RMP = 4,67; 4,41-4,93), estado de Acre (RMP = 2,12; 2,00-2,24) y región norte (RMP = 2,60; 2,45-2,75). Las estimativas apuntan a que neoplasias susceptibles de prevención, como la cervical, y vinculadas al subdesarrollo, como la de estómago e hígado, correspondieron a cerca de un 49,4% de los óbitos entre indígenas. Comparados con la población de referencia, la mortalidad por cáncer de hígado, estómago, colorrectal y leucemias fue más que el doble entre los hombres indígenas; por cáncer cervical, estómago, hígado y leucemias estuvo por encima de un 30% entre las mujeres indígenas.


Assuntos
Humanos , Masculino , Feminino , Recém-Nascido , Lactente , Pré-Escolar , Criança , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Adulto Jovem , Neoplasias/mortalidade , Brasil/epidemiologia , Índios Sul-Americanos , Fatores Sexuais , Incidência , Prevalência , Fatores de Risco , Causas de Morte , Grupos Populacionais , Povos Indígenas/estatística & dados numéricos , Neoplasias/classificação , Neoplasias/diagnóstico
20.
J. vasc. bras ; 18: e20180117, 2019. ilus
Artigo em Inglês | LILACS | ID: biblio-1002492

RESUMO

Acute compartment syndrome of the lower extremities after urological surgery in the lithotomy position is a rare but potentially devastating clinical and medicolegal problem. We report the case of a 67-year-old male who underwent laparoscopic prostatectomy surgery to treat cancer, spending 180 minutes in surgery. Postoperatively, the patient developed acute compartment syndrome of both legs, needing emergency bilateral four-compartment fasciotomies, with repeated returns to the operating room for second-look procedures. The patient also exhibited delayed wound closure. He regained full function within 6 months, returning to unimpaired baseline activity levels. This report aims to highlight the importance of preoperative awareness of this severe complication which, in conjunction with early recognition and immediate surgical management, may mitigate long-term adverse sequelae and improve postoperative outcomes


A síndrome compartimental aguda dos membros inferiores após cirurgia urológica na posição de litotomia é um problema clínico e médico-legal raro, mas potencialmente devastador. Reportamos o caso de um homem de 67 anos submetido a uma prostatectomia laparoscópica por câncer. A cirurgia durou 180 min. No pós-operatório, o paciente desenvolveu síndrome compartimental aguda de ambos os membros inferiores, necessitando de fasciotomias de urgência, com retornos repetidos à sala de cirurgia para procedimentos adicionais. O paciente também apresentou fechamento tardio da ferida. Ele recuperou a função completa dentro de 6 meses e retornou a um nível de atividade basal irrestrito. Este artigo tem a importância de ressaltar a consciência pré-operatória desta grave complicação que, em conjunto com o reconhecimento precoce e o tratamento cirúrgico imediato, pode mitigar sequelas adversas em longo prazo e melhorar os resultados pós-operatórios


Assuntos
Humanos , Masculino , Idoso , Complicações Pós-Operatórias/diagnóstico , Procedimentos Cirúrgicos Urológicos/efeitos adversos , Procedimentos Cirúrgicos Urológicos/métodos , Síndromes Compartimentais , Extremidade Inferior , Prostatectomia/métodos , Neoplasias da Próstata , Pressão Sanguínea , Fatores de Risco , Laparoscopia/métodos , Fáscia , Posicionamento do Paciente/métodos , Fasciotomia/métodos
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