Outcomes of Elderly Patients Undergoing Emergency Surgery for Complicated Colorectal Cancer: A Retrospective Cohort Study.

OBJECTIVE: Colorectal cancer is one of the most frequent types of malignant neoplasms. Age is a risk factor for this disease, with 75% of cases diagnosed in patients older than 65 years. Complications such as obstruction, hemorrhage, and perforation are present in more than one-third of cases and require emergency treatment. We aim to analyze the profile of elderly patients undergoing surgery for complicated colorectal cancer, and to evaluate factors related to worse short-term prognosis. METHODS: A retrospective analysis of patients who underwent emergency surgical treatment for complicated colorectal cancer was performed. Demographics, clinical, radiological and histological data were collected. RESULTS: Sixty-seven patients were analyzed. The median age was 72 years, and almost half (46%) of the patients were female. Obstruction was the most prevalent complication at initial presentation (72%). The most common sites of neoplasia were the left and sigmoid colon in 22 patients (32.8%), and the right colon in 17 patients (25.4%). Resection was performed in 88% of cases, followed by primary anastomosis in almost half. The most frequent clinical stages were II (48%) and III (22%). Forty-three patients (65.7%) had some form of postoperative complication. Clavien-Dindo grades 1, 2, and 4, were the most frequent. Complete oncologic resection was observed in 80% of the cases. The thirty-day mortality rate was 10.4%. Advanced age was associated with worse morbidity and mortality. CONCLUSION: Elderly patients with complicated colorectal cancer undergoing emergency surgery have high morbidity and mortality rates. Advanced age is significantly associated with worse outcomes.

Outcomes of elderly patients undergoing emergency surgery for complicated colorectal cancer: a retrospective cohort study

OBJECTIVE: Colorectal cancer is one of the most frequent types of malignant neoplasms. Age is a risk factor for this disease, with 75% of cases diagnosed in patients older than 65 years. Complications such as obstruction, hemorrhage, and perforation are present in more than one-third of cases and require emergency treatment. We aim to analyze the profile of elderly patients undergoing surgery for complicated colorectal cancer, and to evaluate factors related to worse short-term prognosis. METHODS: A retrospective analysis of patients who underwent emergency surgical treatment for complicated colorectal cancer was performed. Demographics, clinical, radiological and histological data were collected. RESULTS: Sixty-seven patients were analyzed. The median age was 72 years, and almost half (46%) of the patients were female. Obstruction was the most prevalent complication at initial presentation (72%). The most common sites of neoplasia were the left and sigmoid colon in 22 patients (32.8%), and the right colon in 17 patients (25.4%). Resection was performed in 88% of cases, followed by primary anastomosis in almost half. The most frequent clinical stages were II (48%) and III (22%). Forty-three patients (65.7%) had some form of postoperative complication. Clavien-Dindo grades 1, 2, and 4, were the most frequent. Complete oncologic resection was observed in 80% of the cases. The thirty-day mortality rate was 10.4%. Advanced age was associated with worse morbidity and mortality. CONCLUSION: Elderly patients with complicated colorectal cancer undergoing emergency surgery have high morbidity and mortality rates. Advanced age is significantly associated with worse outcomes.

Postoperative disseminated intravascular coagulation in a pregnant patient with Blue Rubber Bleb Nevus Syndrome presenting with acute intestinal obstruction: Case report and literature review.

BACKGROUND: Blue Rubber Bleb Nevus Syndrome (BRBNS) is a rare condition which usually manifests as multiple hemangioma-like skin and gastrointestinal lesions. The latter often present with chronic bleeding. There is no consensus regarding the optimal management of such patients. Although rare, complications such as intestinal intussusception might occur, demanding surgical treatment. Postoperative complications such as coagulation disorders can increase morbidity and should be timely addressed. This is the first report of a life-threatening postoperative disseminated intravascular coagulation in such patients. The main objectives of this case report are to present diagnostic and treatment features of this condition and, more importantly, address the optimal management of postoperative disseminated intravascular coagulation. CASE PRESENTATION: Twenty-five year-old female pregnant patient presents to the emergency department with colicky pain and oligohydramnios. After C-section, persistent symptoms and further investigation led to the diagnosis of intestinal intussusception. After surgical management she showed clinical and laboratory signs of disseminated intravascular coagulation (DIVC), which was corrected with transfusional therapy and intraperitoneal clot evacuation. After optimal management, she was discharged home. Sirolimus was initiated further improving her condition. CONCLUSION: This rare presentation of acute intestinal intussusception in a patient with Blue Rubber Bleb Nevus Syndrome was further complicated with postoperative coagulation disorder. Prompt surgical evaluation is essential especially when complications are suspected. Operative treatment might be necessary in the emergent setting. Close monitoring of infectious and coagulation parameters is essential in the postoperative period, and aggressive treatment should be timely initiated when disseminated intravascular coagulation is suspected.

Safety in selective surgical exploration in penetrating neck trauma.

BACKGROUND: Selective management of penetrating neck injuries has been considered the standard of care with minimal risks to patient safety. In a previous non-randomized prospective study conducted at our center, selective management proved to be safe and reduced unnecessary exploratory cervicotomies. In the present study, the role of clinical examination and selective diagnostic tests were assessed by reviewing demographic and clinical data. A comparison of results between two groups (mandatory surgical exploration versus selective surgical exploration) was made to check the safety of selective management in terms of the rates of morbidity and mortality. METHODS: A retrospective analysis at the Emergency Department of the Hospital das Clínicas of the University of Sao Paulo was performed by a chart review of our trauma registry, identifying 161 penetrating neck trauma victims. RESULTS: Of the 161 patients, 81.6 % were stabbed and 18.4 % had gunshot injuries. Stratifying the wound entry points by neck zones, we observed that zone I was penetrated in 32.8 %, zone II in 44.1 % and zone III in 23.1 % of all the cases. Thirty one patients (19.2 %) had immediate surgical exploration, which had a mean length of stay of 6 days, a complication rate of 12.9 % and a mortality rate of 9.4 %. Of the 130 who underwent selective surgical exploration 34 (26.1 %) required operative procedures after careful physical examination and diagnostic testing based on clinical indications. The mean length of stay for the selective surgical exploration group was 2 days with a complication rate of 17.6 % with no mortality, and virtually all of them were related to associated injuries in distant body segment. No statistical significance was found comparing mortality and complication rates between the two groups. Selective approach avoided 59 % of unnecessary exploratory cervicotomies. CONCLUSION: Careful evaluation of asymptomatic and stable patients with minor signs of injury can safely avoid unnecessary neck explorations with low rates of morbidity. This should be the standard management of such patients.

Valor diagnóstico da tomografia de coluna cervical em vítimas de trauma contuso / Diagnostic value of tomography of the cervical spine in victims of blunt trauma

OBJETIVO. Avaliar o valor da tomografia computadorizada no diagnóstico de lesões da coluna e medula cervicais em vítimas de trauma contuso. MÉTODOS. Revisão dos prontuários de vítimas de trauma contuso atendidas de janeiro de 2006 a dezembro de 2008. Foram analisados os seguintes dados: epidemiológicos, mecanismo de trauma, transporte das vítimas para o hospital, atendimento intra-hospitalar, critérios de indicação da TC, diagnóstico, tratamento, e evolução das vítimas em estudo. As vítimas foram distribuídas em dois grupos: Grupo I - sem lesão na coluna cervical; Grupo II - com lesão na coluna cervical . RESULTADOS. Foram analisados os prontuários de 3.101 vítimas. A tomografia computadorizada foi indicada em 1.572 (51 por cento) pacientes, Foi observado predomínio masculino entre as vítimas (79 por cento), com média etária de 38,53 anos no Grupo I e 37,60 anos no Grupo II. A distribuição dos mecanismos de trauma foi semelhante nos dois grupos. Lesões encontradas: 53 fraturas, oito listeses vertebrais e oito lesões medulares. As sequelas incluíram: três paraplegias, cinco tetraplegias e oito sequelas de lesão cerebral. No Grupo II ocorreram sete óbitos ,no Grupo I 240. A duração média de internação hospitalar foi de 11 dias para o Grupo I e 26,2 dias para o Grupo II. CONCLUSÃO. A TC de coluna cervical em vítimas de trauma contuso foi eficaz na identificação de lesões da coluna e medula cervicais. Assim, apesar do custo da TC cervical, e da baixa incidência de lesões por ela identificáveis, a sua indicação baseada nos critérios usuais parece justificável.

OBJECTIVE: to assess the value of computed tomography in the diagnosis of cervical spine and spinal cord injuries in victims of blunt trauma. METHODS: we reviewed the charts of blunt trauma victims from January 2006 to December 2008. We analyzed the following data: epidemiology, mechanism of trauma, transportation of victims to the hospital, intra-hospital care, indication criteria for CT, diagnosis, treatment and evolution of the victims. The victims were divided into two groups: Group I - without cervical spine injury, Group II - with cervical spine injury. RESULTS: we gathered medical records from 3,101 victims. Computed tomography was performed in 1572 (51 percent) patients, with male predominance (79 percent) and mean age of 38.53 years in Group I and 37.60 years in Group II. The distribution of trauma mechanisms was similar in both groups. Lesions found included: 53 fractures, eight vertebral listeses and eight spinal cord injuries. Sequelae included: paraplegia in three cases, quadriplegia in eight and brain injury in five. There were seven deaths in Group II and 240 in Group I. The average length of hospital stay was 11 days for Group I and 26.2 days for Group II. CONCLUSION. A CT scan of the cervical spine in victims of blunt trauma was effective in identifying lesions of the cervical spine and spinal cord injuries. Thus, despite the cost of neck CT and the low incidence of lesions identified by it, its indication based on the usual criteria seems justified.

Ruptura traumatica de diverticulo duodenal: relato de um caso e revisao da literatura / Traumatic rupture of duodenal diverticulum: report of a case and review of literature

O diverticulo duodenal e uma anormalidade anatomica comum. Sua perfuracao decorrente de processo inflamatorio e bastante rara, com menos de 100 relatos na literatura consultada. Mais rara ainda e a perfuracao traumatica, representada apenas por tres casos relatados. Os autores relatam um caso de ruptura traumatica de diverticulo duodenal, e fazem uma revisao da literatura, focalizando a patogenia, o diagnostico e a terapeutica desta grave patologia

Baläo de tamponamento em ferimentos transfixantes de fígado: resultados imediatos / Balloon tamponade in transfixing wounds of the liver: immediates results

O tratamento cirúrgico das lesöes traumáticas transfixantes do fígado e acompanhadas de grandes hemorragias costuma ser tecnicamente difícil. Näo raramente ocorre óbito de pacientes por exsanguinaçäo intra-operatória. A adoçäo das técnicas convencionais de tamponamento ou ressecçäo costuma levar a índices de elevados de complicaçöes pós-operatórias. Motivados por estes fatos os autores desenvolveram dispositivo de tamponamento de fácil confecçäo e aplicaçäo. Esta comunicaçäo relata a experiência nos primeiros nove casos em que foi utilizado. O dispositivo mostrou-se eficiente em todos os casos, ocorreu um óbito, por lesöes associadas, uma complicaçäo que exigiu reintervençäo e seis fístulas biliares que se resolveram espontaneamente. Tais resultados confirmam a utilidade do método proposto e permitem recomendar sua utilizaçäo

Complicaçöes raras em hérnias: relato de um caso de apendicite aguda em hérnia incisional / Rare complications in hernias: report of a case of acute appendicitis in incisional hernia

Descreve-se um caso de apendicite aguda ocorrido em uma hérnia incisional de longa duraçäo. Faz-se uma revisäo da literatura, encontrando-se apenas um caso semelhante. Comenta-se a dificuldade do diagnóstico diferencial com estrangulamento de hérnia

Ferimentos de veia cava inferior: análise de 75 casos / Injuries of the inferior vena cava: analysis of 75 cases

Apesar da diminuiçäo dos índices de mortalidade observados nas duas últimas décadas, os ferimentos de veia cava inferior (VCI) revestem-se ainda de muita gravidade. A análise de 75 casos com lesöes traumáticas de VCI, que constituem o motivo desta apresentaçäo, revelou índice de mortalidade de 32%, ocasionada principalmente por abundantes hemorragias e lesöes viscerais associadas. Embora tais resultados sejam aceitáveis e comparáveis aos da literatura, cumpre frisar que as lesöes de VCI retro-hepática continuam representando grande desafio terapêutico, comprovado pelo índice de mortalidade que, nesses casos, foi de 66%. O conhecimento da anatomia da VCI e de suas tributárias é importante para o tratamento cirúrgico dessas lesöes. Deve-se sempre dar preferência à sutura da veia e evitar, assim, a ligadura, pois esta predispöe à trombose venosa profunda e suas seqüelas