Detalles de la búsqueda
1.
Quality Assurance of PBPK Modeling Platforms and Guidance on Building, Evaluating, Verifying and Applying PBPK Models Prudently under the Umbrella of Qualification: Why, When, What, How and By Whom?
Pharm Res
; 39(8): 1733-1748, 2022 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-35445350
2.
CYP3A4-mediated effects of rifampicin on the pharmacokinetics of vilaprisan and its UGT1A1-mediated effects on bilirubin glucuronidation in humans.
Br J Clin Pharmacol
; 84(12): 2857-2866, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30171692
3.
Optimization of linezolid therapy in the critically ill: the effect of adjusted infusion regimens.
J Antimicrob Chemother
; 72(8): 2304-2310, 2017 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28541510
4.
Predictors of Inadequate Linezolid Concentrations after Standard Dosing in Critically Ill Patients.
Antimicrob Agents Chemother
; 60(9): 5254-61, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27324768
5.
Comparison of Pantoprazole Concentrations in Simultaneous Cerebrospinal Fluid and Serum Samples.
Pharmacology
; 98(1-2): 70-2, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27104875
6.
In-Depth Analysis of the Selection of PBPK Modeling Tools: Bibliometric and Social Network Analysis of the Open Systems Pharmacology Community.
J Clin Pharmacol
; 2024 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38708848
7.
Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.
CPT Pharmacometrics Syst Pharmacol
; 13(1): 79-92, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37794724
8.
Assessment of the CYP3A4 Induction Potential by Carbamazepine: Insights from Two Clinical DDI Studies and PBPK Modeling.
Clin Pharmacol Ther
; 115(5): 1025-1032, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38105467
9.
Physiologically based pharmacokinetic modeling of tacrolimus for food-drug and CYP3A drug-drug-gene interaction predictions.
CPT Pharmacometrics Syst Pharmacol
; 12(5): 724-738, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36808892
10.
Physiologically-based pharmacokinetic modeling of quinidine to establish a CYP3A4, P-gp, and CYP2D6 drug-drug-gene interaction network.
CPT Pharmacometrics Syst Pharmacol
; 12(8): 1143-1156, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37165978
11.
Leveraging the use of in vitro and computational methods to support the development of enabling oral drug products: An InPharma commentary.
Eur J Pharm Sci
; 188: 106505, 2023 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37343604
12.
Palliative care consultation service and palliative care unit: why do we need both?
Oncologist
; 17(3): 428-35, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22357732
13.
Recommending early integration of palliative care - does it work?
Support Care Cancer
; 20(3): 507-13, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-21336529
14.
Drug interactions in palliative care--it's more than cytochrome P450.
Palliat Med
; 26(6): 813-25, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21737479
15.
Physiologically-based pharmacokinetic modeling to predict CYP3A4-mediated drug-drug interactions of finerenone.
CPT Pharmacometrics Syst Pharmacol
; 11(2): 199-211, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34783193
16.
A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions.
CPT Pharmacometrics Syst Pharmacol
; 10(6): 633-644, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33946131
17.
Predictive Performance of Physiology-Based Pharmacokinetic Dose Estimates for Pediatric Trials: Evaluation With 10 Bayer Small-Molecule Compounds in Children.
J Clin Pharmacol
; 61 Suppl 1: S70-S82, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34185905
18.
A Novel Study Design Using Continuous Intravenous and Intraduodenal Infusions of Midazolam and Voriconazole for Mechanistic Quantitative Assessment of Hepatic and Intestinal CYP3A Inhibition.
J Clin Pharmacol
; 60(9): 1237-1253, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32427354
19.
A Physiologically Based Pharmacokinetic Model of Voriconazole Integrating Time-Dependent Inhibition of CYP3A4, Genetic Polymorphisms of CYP2C19 and Predictions of Drug-Drug Interactions.
Clin Pharmacokinet
; 59(6): 781-808, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-31853755
20.
Sorafenib and everolimus in patients with advanced solid tumors and KRAS-mutated NSCLC: A phase I trial with early pharmacodynamic FDG-PET assessment.
Cancer Med
; 9(14): 4991-5007, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32436621